| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fernández-Bussy R et al. | Expression of phosphatidylcholine biosynthetic enzymes during early embryogenesis in the amphibian Bufo arenarum. | 2015 | Zygote | pmid:24229731 |
| Li SY et al. | [Cell membrane phospholipid variation and protein kinase C expression effects on hepatic metastasis of large intestinal carcinoma]. | 2004 | Zhonghua Wai Ke Za Zhi | pmid:15009987 |
| Malisiova F et al. | Liposomal formulations from phospholipids of Greek almond oil. Properties and biological activity. | 2004 May-Jun | Z. Naturforsch., C, J. Biosci. | pmid:18998396 |
| Hasim S et al. | Influence of phosphatidylserine and phosphatidylethanolamine on farnesol tolerance in Candida albicans. | 2018 | Yeast | pmid:29143357 |
| Redón M et al. | Effect of low temperature upon vitality of Saccharomyces cerevisiae phospholipid mutants. | 2012 | Yeast | pmid:23027642 |
| Tosch W et al. | Molecular species of phosphatidylethanolamine from continuous cultures of Saccharomyces pastorianus syn. carlsbergensis strains. | 2006 | Yeast | pmid:16491465 |
| Zhang N et al. | [The enhancing effect of tomato lectin modified liposomes of insulin on oral absorption in mice]. | 2004 | Yao Xue Xue Bao | pmid:15338884 |
| Zhang N et al. | [Enhancing effect of Ulex europaeus agglutinin I modified liposomes on oral insulin absorption in mice]. | 2004 | Yao Xue Xue Bao | pmid:15813031 |
| MILSTONE JH | Bovine serum as a complement for the combined effects of thrombokinase and cephalin. | 1952 | Yale J Biol Med | pmid:13015949 |
| Nakano M | [Disk-like complex formation by apolipoprotein-lipid membrane interaction and relevance to high-density lipoprotein formation]. | 2008 | Yakugaku Zasshi | pmid:18451614 |
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| Belov GA | Less Grease, Please. Phosphatidylethanolamine Is the Only Lipid Required for Replication of a (+)RNA Virus. | 2015 | Viruses | pmid:26131959 |
| Laurinavicius S et al. | The origin of phospholipids of the enveloped bacteriophage phi6. | 2004 | Virology | pmid:15262506 |
| Sprott GD et al. | Liposome adjuvants prepared from the total polar lipids of Haloferax volcanii, Planococcus spp. and Bacillus firmus differ in ability to elicit and sustain immune responses. | 2004 | Vaccine | pmid:15149772 |
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| Sun J et al. | Ultrasound-mediated destruction of oxygen and paclitaxel loaded lipid microbubbles for combination therapy in hypoxic ovarian cancer cells. | 2016 | Ultrason Sonochem | pmid:26384914 |
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| Dennis MW et al. | Prothrombinase enhancement through quantitative and qualitative changes affecting very low density lipoprotein in complex with C-reactive protein. | 2004 | Thromb. Haemost. | pmid:14983228 |
| Wahlmüller FC et al. | New lipid interaction partners stimulate the inhibition of activated protein C by cell-penetrating protein C inhibitor. | 2014 | Thromb. Haemost. | pmid:24136361 |
| Nishida I | [Reverse genetic approaches for the significance of phospholipid metabolism at low temperatures]. | 2007 | Tanpakushitsu Kakusan Koso | pmid:17566349 |
| Iwamoto K et al. | [Relationship between localized phosphatidylethanolamine exposure and yeast cell polarity]. | 2004 | Tanpakushitsu Kakusan Koso | pmid:15346886 |
| Mizushima N | [Methods for monitoring macroautophagy]. | 2006 | Tanpakushitsu Kakusan Koso | pmid:16922435 |
| Krafft C et al. | Near infrared Raman spectra of human brain lipids. | 2005 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:15820887 |
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| Zhao S et al. | [Metabonomics and phospholipid metabolic profiling of abnormal glucose metabolism based on high performance liquid chromatography-electrospray mass spectrometry]. | 2011 | Se Pu | pmid:21770239 |
| Wang C et al. | Characterization of phosphatidylethanolamine molecular species in human blood by on-line high performance liquid chromatography/quadrupole-linear ion trap mass spectrometry. | 2004 | Se Pu | pmid:15709398 |
| Zhou M et al. | Mass spectrometry of intact V-type ATPases reveals bound lipids and the effects of nucleotide binding. | 2011 | Science | pmid:22021858 |
| Tsuboyama K et al. | The ATG conjugation systems are important for degradation of the inner autophagosomal membrane. | 2016 | Science | pmid:27885029 |
| Begum H et al. | Discovering and validating between-subject variations in plasma lipids in healthy subjects. | 2016 | Sci Rep | pmid:26743939 |
| Farine L et al. | Phosphatidylethanolamine and phosphatidylcholine biosynthesis by the Kennedy pathway occurs at different sites in Trypanosoma brucei. | 2015 | Sci Rep | pmid:26577437 |
| Montaner A et al. | Specific Phospholipids Regulate the Acquisition of Neuronal and Astroglial Identities in Post-Mitotic Cells. | 2018 | Sci Rep | pmid:29323239 |
| Kim JS et al. | The Tnfaip8-PE complex is a novel upstream effector in the anti-autophagic action of insulin. | 2017 | Sci Rep | pmid:28740220 |
| Dória ML et al. | Epithelial ovarian carcinoma diagnosis by desorption electrospray ionization mass spectrometry imaging. | 2016 | Sci Rep | pmid:27976698 |
| Serrán-Aguilera L et al. | Plasmodium falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine Causing Parasite Death. | 2016 | Sci Rep | pmid:27616047 |
| Shin H et al. | Genome-wide transcriptome analysis revealed organelle specific responses to temperature variations in algae. | 2016 | Sci Rep | pmid:27883062 |
| Dashti M et al. | A phospholipidomic analysis of all defined human plasma lipoproteins. | 2011 | Sci Rep | pmid:22355656 |
| Kojima R et al. | A phospholipid transfer function of ER-mitochondria encounter structure revealed in vitro. | 2016 | Sci Rep | pmid:27469264 |
| Dimitrova M et al. | CD300c is uniquely expressed on CD56 bright Natural Killer Cells and differs from CD300a upon ligand recognition. | 2016 | Sci Rep | pmid:27040328 |
| Shahine A et al. | A molecular basis of human T cell receptor autoreactivity toward self-phospholipids. | 2017 | Sci Immunol | pmid:29054999 |
| Admasu TD et al. | Lipid profiling of C. elegans strains administered pro-longevity drugs and drug combinations. | 2018 | Sci Data | pmid:30351306 |
| Bălănescu P et al. | Association of anti phosphatidyl ethanolamine antibodies and low complement levels in systemic sclerosis patients--results of a cross-sectional study. | 2015 | Scand. J. Clin. Lab. Invest. | pmid:26067612 |