| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:15131978 | ||||
| pmid: | ||||
| Cesari AB et al. | Changes in the lipid composition of Bradyrhizobium cell envelope reveal a rapid response to water deficit involving lysophosphatidylethanolamine synthesis from phosphatidylethanolamine in outer membrane. | Res. Microbiol. | pmid:29864488 | |
| FRISCH AW and QUILLIGAN JJ | A modified cephalin cholesterol test (Hanger) in the study of hepatic disease. | 1946 | Am. J. Med. Sci. | pmid:20996956 |
| Havens WP and Marck RE | A COMPARISON OF THE CEPHALIN-CHOLESTEROL FLOCCULATION AND THYMOL TURBIDITY TESTS IN PATIENTS WITH EXPERIMENTALLY INDUCED INFECTIOUS HEPATITIS. | 1946 | J. Clin. Invest. | pmid:16695379 |
| PRINCE GE | Cephalin-cholesterol flocculation in premature infants and children receiving immune globulin. | 1947 | J. Pediatr. | pmid:20249037 |
| Saifer A | A METHOD FOR THE QUANTITATIVE DETERMINATION OF THE CEPHALIN-CHOLESTEROL FLOCCULATION REACTION. | 1948 | J. Clin. Invest. | pmid:16695596 |
| STEINBERG BL | Intravenous procaine; its effect on liver function in man as determined by the cephalin flocculation test. | 1949 | Anesthesiology | pmid:15393676 |
| SAIFER A | Studies with the quantitative cephalin cholesterol flocculation reaction; effect of variation in temperature at which Hanger reaction occurs; the protein patterns of normal and abnormal liver-disease sera. | 1949 | Bull N Y Acad Med | pmid:18152263 |
| NEEFE JR et al. | Comparison of the thymol, cephalin-cholesterol flocculation and colloidal red tests in acute viral hepatitis. | 1950 | Am. J. Med. | pmid:15413625 |
| CHRISTHILF SM et al. | Liver function during pregnancy and the puerperium, as measured by the cephalin-cholesterol flocculation, the thymol turbidity, and the bromsulfalein tests. | 1950 | Am. J. Obstet. Gynecol. | pmid:15410828 |
| MILSTONE JH | Bovine serum as a complement for the combined effects of thrombokinase and cephalin. | 1952 | Yale J Biol Med | pmid:13015949 |
| AXELROD J et al. | The direct determination of phosphatidyl ethanolamine and phosphatidyl serine in plasma and red blood cells. | 1953 | J. Biol. Chem. | pmid:13117868 |
| NORMAN JM and DAWSON RM | A method for measuring the deposition of 32P in phosphatidylethanolamine and its application to rat-brain tissue. | 1953 | Biochem. J. | pmid:13058914 |
| BAER E et al. | Migration during hydrolysis of esters of glycerophosphoric acid. III. Cephalin and glycerylphosphorylethanolamine. | 1953 | J. Biol. Chem. | pmid:13034779 |
| DIECKMANN WJ and POTTINGER RE | Serial studies of the cephalin flocculation and thymol turbidity tests in pregnant patients. | 1954 | Am. J. Obstet. Gynecol. | pmid:13207248 |
| MILSTONE JH | Effect of blood thrombokinase, as influenced by soy bean trypsin inhibitor, ultracentrifugation, and accessory factors. | 1955 | J. Gen. Physiol. | pmid:13242762 |
| SCHOLFIELD CR and DUTTON HJ | Preparation of phosphatidyl ethanolamine from soy bean phosphatides. | 1955 | J. Biol. Chem. | pmid:14381400 |
| POOLE JC and ROBINSON DS | Further observations on the effects of ethanolamine phosphatide on plasma coagulation. | 1956 | Q J Exp Physiol Cogn Med Sci | pmid:13485345 |
| O'BRIEN JR | The similarity of the action of phosphatidyl-ethanolamine and platelets in blood coagulation. | 1956 | J. Clin. Pathol. | pmid:13306791 |
| ROBINSON DS and POOLE JC | The similar effect of chylomicra and ethanolamine phosphatide on the generation of thrombin during coagulation. | 1956 | Q J Exp Physiol Cogn Med Sci | pmid:13485325 |
| MCCANDLESS EL and ZILVERSMIT DB | The effect of cholesterol on the turnover of lecithin, cephalin and sphingomyelin in the rabbit. | 1956 | Arch. Biochem. Biophys. | pmid:13328128 |
| LITHERLAND OK and BOGOCH A | A comparison of the cephalin-cholesterol flocculation and thymol turbidity tests in patients with portal cirrhosis. | 1959 | Can Med Assoc J | pmid:13662955 |
| HAWKE JC | The fatty acids of phosphatidylethanolamine and phosphatidylcholine from hen's egg. | 1959 | Biochem. J. | pmid:13638270 |
| CRUZ WO et al. | Crude cephalin as the active substance of organ extracts able to convert venous blood into hemostatic blood. | 1959 | Arch. Biochem. Biophys. | pmid:13813116 |
| HOKIN LE and HOKIN MR | Studies on the carrier function of phosphatidic acid in sodium transport. I. The turnover of phosphatidic acid and phosphoinositide in the avian salt gland on stimulation of secretion. | 1960 | J. Gen. Physiol. | pmid:13715209 |
| GIBSON KD et al. | The enzymatic conversion of phospholipid ethanolamine to phospholipid choline in rat liver. | 1961 | J. Biol. Chem. | pmid:13705126 |
| GOBBI F and STEFANINI M | Effects of cephalin on the hemostatic defect of the hemophilia syndrome in vitro and in vivo. | 1961 | Acta Haematol. | pmid:13706151 |
| TOBIAS JM et al. | Phospholipidcholesterol membrane model. Control of resistance by ions or current flow. | 1962 | J. Gen. Physiol. | pmid:13921460 |
| GOBBI F and STEFANINI M | Circulating anti-AHG anticoagulant in a patient with lupus erythematosus disseminatus. Effect of a cephalin complex in vivo. | 1962 | Acta Haematol. | pmid:13899358 |
| ANSELL GB and SPANNER S | The occurence of a long-chain ether analogue of phosphatidylethanolamine in brain tissue. | 1963 | Biochem. J. | pmid:14013279 |
| MERKL I and LANDS WE | Metabolism of glycerolipids. IV. Synthesis of phosphatidylethanolamine. | 1963 | J. Biol. Chem. | pmid:13935003 |
| ANSELL GB and MARSHALL EF | SOME EFFECTS OF CHLORPROMAZINE ON BRAIN PHOSPHOLIPID METABOLISM. II. LABELLING OF CHOLINE- AND ETHANOLAMINE-CONTAINING PHOSPHOLIPIDS BY RADIOACTIVE PRECURSORS IN VITRO. | 1963 | J. Neurochem. | pmid:14087692 |
| ROBINS DC | PHOSPHATIDYLETHANOLAMINE AND LYSOPHOSPHATIDYLETHANOLAMINE. | 1963 | J. Pharm. Pharmacol. | pmid:14079614 |
| CRUZ WO et al. | HAEMOSTATIC ACTIVITY OF CRUDE CEPHALIN COMPONENTS. | 1963 | Br. J. Haematol. | pmid:14076124 |
| ROBINS DC and THOMAS IL | Physico-chemical experiments with phosphatidyl ethanolamine sols. | 1963 | J. Pharm. Pharmacol. | pmid:13974409 |
| SPITZER HL and BALINT JA | A rapid quantitative separation of phosphatidyl ethanolamine and phosphatidyl serine by column chromatography. | 1963 | Anal. Biochem. | pmid:13990206 |
| FEINSTEIN MB | REACTION OF LOCAL ANESTHETICS WITH PHOSPHOLIPIDS. A POSSIBLE CHEMICAL BASIS FOR ANESTHESIA. | 1964 | J. Gen. Physiol. | pmid:14225262 |
| BAER E and STANACEY NZ | PHOSPHONOLIPIDS. I. SYNTHESIS OF A PHOSPHONIC ACID ANALOGUE OF CEPHALIN. | 1964 | J. Biol. Chem. | pmid:14245363 |
| FRIEDMAN HH et al. | ODOR MEASUREMENT POSSIBILITIES VIA ENERGY CHANGES IN CEPHALIN MONOLAYERS. | 1964 | Ann. N. Y. Acad. Sci. | pmid:14220554 |
| MATCHES JR et al. | PHOSPHOLIPIDS IN VEGETATIVE CELLS AND SPORES OF BACILLUS POLYMYXA. | 1964 | J. Bacteriol. | pmid:14102851 |
| HUSTON CK et al. | LIPIDS OF SARCINA LUTEA. 3. COMPOSITION OF THE COMPLEX LIPIDS. | 1965 | J. Bacteriol. | pmid:14273659 |
| ANSELL GB and SPANNER S | THE MAGNESIUM-ION-DEPENDENT CLEAVAGE OF THE VINYL ETHER LINKAGE OF BRAIN ETHANOLAMINE PLASMALOGEN. | 1965 | Biochem. J. | pmid:14342238 |
| TAYLOR JF and HODGSON E | THE ORIGIN OF PHOSPHOLIPID ETHANOLAMINE IN THE BLOWFLY, PHORMIA REGINA (MEIG.). | 1965 | J. Insect Physiol. | pmid:14330760 |
| MOORE JH and WILLIAMS DL | STUDIES ON THE COMPOSITION AND STRUCTURE OF THE PHOSPHATIDYLCHOLINE, PHOSPHATIDYLETHANOLAMINE AND TRIGLYCERIDE ISOLATED FROM RABBIT LIVER. | 1965 | Biochim. Biophys. Acta | pmid:14290822 |
| REHBINDER D and GREENBERG DM | STUDIES ON THE METHYLATION OF ETHANOLAMINE PHOSPHATIDES BY LIVER PREPARATIONS. | 1965 | Arch. Biochem. Biophys. | pmid:14281933 |
| ROOTS BI and JOHNSTON PV | LIPIDS OF ISOLATED NEURONS. | 1965 | Biochem. J. | pmid:14342249 |
| Marinetti GV | Arrangement of phosphatidylserine and phosphatidylethanolamine in the erythrocyte membrane. | 1977 | Biochim. Biophys. Acta | pmid:16250335 |
| Pietsch A and Lorenz RL | Rapid separation of the major phospholipid classes on a single aminopropyl cartridge. | 1993 | Lipids | pmid:27483556 |
| Xu Z et al. | Synthesis and characterization of oligomaltose-grafted lipids with application to liposomes. | 2002 | J Colloid Interface Sci | pmid:16290762 |