| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Largo E et al. | Ion channel activity of the CSFV p7 viroporin in surrogates of the ER lipid bilayer. | 2016 | Biochim. Biophys. Acta | pmid:26464198 |
| Ariöz C et al. | Heterologous overexpression of a monotopic glucosyltransferase (MGS) induces fatty acid remodeling in Escherichia coli membranes. | 2014 | Biochim. Biophys. Acta | pmid:24726609 |
| Strömstedt AA et al. | Bactericidal activity of cyclotides where phosphatidylethanolamine-lipid selectivity determines antimicrobial spectra. | 2017 | Biochim. Biophys. Acta | pmid:28669767 |
| Laurinavicius S et al. | Transbilayer distribution of phospholipids in bacteriophage membranes. | 2007 | Biochim. Biophys. Acta | pmid:17658459 |
| Putta P et al. | Phosphatidic acid binding proteins display differential binding as a function of membrane curvature stress and chemical properties. | 2016 | Biochim. Biophys. Acta | pmid:27480805 |
| MOORE JH and WILLIAMS DL | STUDIES ON THE COMPOSITION AND STRUCTURE OF THE PHOSPHATIDYLCHOLINE, PHOSPHATIDYLETHANOLAMINE AND TRIGLYCERIDE ISOLATED FROM RABBIT LIVER. | 1965 | Biochim. Biophys. Acta | pmid:14290822 |
| Msika O et al. | NGF blocks polyunsaturated fatty acids biosynthesis in n-3 fatty acid-supplemented PC12 cells. | 2012 | Biochim. Biophys. Acta | pmid:22564256 |
| Kannan M et al. | Endoplasmic reticulum stress affects the transport of phosphatidylethanolamine from mitochondria to the endoplasmic reticulum in S.cerevisiae. | 2016 | Biochim. Biophys. Acta | pmid:27678054 |
| Unsay JD et al. | Pro-apoptotic cBid and Bax exhibit distinct membrane remodeling activities: An AFM study. | 2017 | Biochim. Biophys. Acta | pmid:27755971 |
| Wriessnegger T et al. | Lipid analysis of mitochondrial membranes from the yeast Pichia pastoris. | 2009 | Biochim. Biophys. Acta | pmid:19168151 |
| Dimmer KS and Rapaport D | Mitochondrial contact sites as platforms for phospholipid exchange. | 2017 | Biochim. Biophys. Acta | pmid:27477677 |
| Palusińska-Szysz M et al. | The lipid composition of Legionella dumoffii membrane modulates the interaction with Galleria mellonella apolipophorin III. | 2016 | Biochim. Biophys. Acta | pmid:27094351 |
| Hicks AM et al. | Unique molecular signatures of glycerophospholipid species in different rat tissues analyzed by tandem mass spectrometry. | 2006 | Biochim. Biophys. Acta | pmid:16860597 |
| Bradley RM et al. | Acylglycerophosphate acyltransferase 4 (AGPAT4) is a mitochondrial lysophosphatidic acid acyltransferase that regulates brain phosphatidylcholine, phosphatidylethanolamine, and phosphatidylinositol levels. | 2015 | Biochim. Biophys. Acta | pmid:26417903 |
| Rosenberger S et al. | Phosphatidylethanolamine synthesized by three different pathways is supplied to peroxisomes of the yeast Saccharomyces cerevisiae. | 2009 | Biochim. Biophys. Acta | pmid:19830909 |
| van Uitert I et al. | The influence of different membrane components on the electrical stability of bilayer lipid membranes. | 2010 | Biochim. Biophys. Acta | pmid:19835838 |
| Hall K et al. | Gly(6) of kalata B1 is critical for the selective binding to phosphatidylethanolamine membranes. | 2012 | Biochim. Biophys. Acta | pmid:22538355 |
| Ãlvarez R et al. | G protein-membrane interactions I: Gαi1 myristoyl and palmitoyl modifications in protein-lipid interactions and its implications in membrane microdomain localization. | 2015 | Biochim. Biophys. Acta | pmid:26253820 |
| Stark B et al. | Association of vasoactive intestinal peptide with polymer-grafted liposomes: structural aspects for pulmonary delivery. | 2007 | Biochim. Biophys. Acta | pmid:17204237 |
| Pasenkiewicz-Gierula M et al. | Computer modelling studies of the bilayer/water interface. | 2016 | Biochim. Biophys. Acta | pmid:26825705 |