| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Barker AP et al. | A novel extracellular phospholipase C of Pseudomonas aeruginosa is required for phospholipid chemotaxis. | 2004 | Mol. Microbiol. | pmid:15306013 |
| Moser R et al. | Discovery of a bifunctional cardiolipin/phosphatidylethanolamine synthase in bacteria. | 2014 | Mol. Microbiol. | pmid:24707916 |
| Bonner PJ et al. | The Dif chemosensory pathway is directly involved in phosphatidylethanolamine sensory transduction in Myxococcus xanthus. | 2005 | Mol. Microbiol. | pmid:16102016 |
| Gibellini F et al. | The ethanolamine branch of the Kennedy pathway is essential in the bloodstream form of Trypanosoma brucei. | 2009 | Mol. Microbiol. | pmid:19555461 |
| Bonner PJ and Shimkets LJ | Phospholipid directed motility of surface-motile bacteria. | 2006 | Mol. Microbiol. | pmid:16925549 |
| Matsumoto K et al. | Lipid domains in bacterial membranes. | 2006 | Mol. Microbiol. | pmid:16925550 |
| Bonner PJ et al. | FibA and PilA act cooperatively during fruiting body formation of Myxococcus xanthus. | 2006 | Mol. Microbiol. | pmid:16925559 |
| Signorell A et al. | Perturbation of phosphatidylethanolamine synthesis affects mitochondrial morphology and cell-cycle progression in procyclic-form Trypanosoma brucei. | 2009 | Mol. Microbiol. | pmid:19400804 |
| Farine L et al. | Phosphatidylserine synthase 2 and phosphatidylserine decarboxylase are essential for aminophospholipid synthesis in Trypanosoma brucei. | 2017 | Mol. Microbiol. | pmid:28142188 |
| Chen YL et al. | Phosphatidylserine synthase and phosphatidylserine decarboxylase are essential for cell wall integrity and virulence in Candida albicans. | 2010 | Mol. Microbiol. | pmid:20132453 |
| Kuroda T et al. | FMP30 is required for the maintenance of a normal cardiolipin level and mitochondrial morphology in the absence of mitochondrial phosphatidylethanolamine synthesis. | 2011 | Mol. Microbiol. | pmid:21306442 |
| Xu Q et al. | Independence and interdependence of Dif and Frz chemosensory pathways in Myxococcus xanthus chemotaxis. | 2008 | Mol. Microbiol. | pmid:18554324 |
| Suárez-Germà C et al. | Modeling FRET to investigate the selectivity of lactose permease of Escherichia coli for lipids. | 2014 | Mol. Membr. Biol. | pmid:24826799 |
| Sawant RR and Torchilin VP | Multifunctionality of lipid-core micelles for drug delivery and tumour targeting. | 2010 | Mol. Membr. Biol. | pmid:20929339 |
| Whitfield T et al. | The influence of different lipid environments on the structure and function of the hepatitis C virus p7 ion channel protein. | 2011 | Mol. Membr. Biol. | pmid:21604991 |
| Funari SS et al. | Farnesol and geranylgeraniol modulate the structural properties of phosphatidylethanolamine model membranes. | 2005 Jul-Aug | Mol. Membr. Biol. | pmid:16154902 |
| Dubielecka PM et al. | Mitoxantrone changes spectrin-aminophospholipid interactions. | 2006 May-Jun | Mol. Membr. Biol. | pmid:16785207 |
| Ogunbona OB et al. | Multitiered and Cooperative Surveillance of Mitochondrial Phosphatidylserine Decarboxylase 1. | 2017 | Mol. Cell. Biol. | pmid:28606933 |
| Ye C et al. | A Metabolic Function for Phospholipid and Histone Methylation. | 2017 | Mol. Cell | pmid:28366644 |
| Alder-Baerens N et al. | Loss of P4 ATPases Drs2p and Dnf3p disrupts aminophospholipid transport and asymmetry in yeast post-Golgi secretory vesicles. | 2006 | Mol. Biol. Cell | pmid:16452632 |