| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Oberfeld B et al. | Phospholipids occupy the internal lumen of the c ring of the ATP synthase of Escherichia coli. | 2006 | Biochemistry | pmid:16460030 |
| Shizuka M et al. | Synthesis of isoprostanyl phosphatidylcholine and isoprostanyl phosphatidylethanolamine. | 2006 | J. Org. Chem. | pmid:16468779 |
| Higuchi O et al. | Aminophospholipid glycation and its inhibitor screening system: a new role of pyridoxal 5'-phosphate as the inhibitor. | 2006 | J. Lipid Res. | pmid:16470027 |
| Tosch W et al. | Molecular species of phosphatidylethanolamine from continuous cultures of Saccharomyces pastorianus syn. carlsbergensis strains. | 2006 | Yeast | pmid:16491465 |
| Arnt L et al. | Membrane activity of biomimetic facially amphiphilic antibiotics. | 2006 | J Phys Chem B | pmid:16494408 |
| Dyall SC et al. | Dietary enrichment with omega-3 polyunsaturated fatty acids reverses age-related decreases in the GluR2 and NR2B glutamate receptor subunits in rat forebrain. | 2007 | Neurobiol. Aging | pmid:16500747 |
| Takahashi K et al. | Purification and ATPase activity of human ABCA1. | 2006 | J. Biol. Chem. | pmid:16500904 |
| Jumpsen JA et al. | Fatty acids in blood and intestine following docosahexaenoic acid supplementation in adults with cystic fibrosis. | 2006 | J. Cyst. Fibros. | pmid:16507353 |
| Tanaka A et al. | Peroxisome division is impaired in a CHO cell mutant with an inactivating point-mutation in dynamin-like protein 1 gene. | 2006 | Exp. Cell Res. | pmid:16529741 |
| Mudgil P et al. | Adsorption of lysozyme to phospholipid and meibomian lipid monolayer films. | 2006 | Colloids Surf B Biointerfaces | pmid:16530395 |
| Sternin E et al. | Changes in molecular order across the lamellar-to-inverted hexagonal phase transition depend on the position of the double-bond in mono-unsaturated phospholipid dispersions. | 2006 | Chem. Phys. Lipids | pmid:16574088 |
| Hirche F et al. | Effect of dietary methionine on plasma and liver cholesterol concentrations in rats and expression of hepatic genes involved in cholesterol metabolism. | 2006 | Br. J. Nutr. | pmid:16611377 |
| Dabholkar RD et al. | Polyethylene glycol-phosphatidylethanolamine conjugate (PEG-PE)-based mixed micelles: some properties, loading with paclitaxel, and modulation of P-glycoprotein-mediated efflux. | 2006 | Int J Pharm | pmid:16616818 |
| Kume H and Sasaki H | Ethanolamine modulates DNA synthesis through epidermal growth factor receptor in rat primary hepatocytes. | 2006 Jan-Feb | In Vitro Cell. Dev. Biol. Anim. | pmid:16618207 |
| Shaikh SR et al. | Molecular organization of cholesterol in unsaturated phosphatidylethanolamines: X-ray diffraction and solid state 2H NMR reveal differences with phosphatidylcholines. | 2006 | J. Am. Chem. Soc. | pmid:16620109 |
| Ishida BY et al. | High density lipoprotein mediated lipid efflux from retinal pigment epithelial cells in culture. | 2006 | Br J Ophthalmol | pmid:16622093 |
| Russano AM et al. | Recognition of pollen-derived phosphatidyl-ethanolamine by human CD1d-restricted gamma delta T cells. | 2006 | J. Allergy Clin. Immunol. | pmid:16675349 |
| Li Z et al. | The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis. | 2006 | Cell Metab. | pmid:16679290 |
| Havens WP and Marck RE | A COMPARISON OF THE CEPHALIN-CHOLESTEROL FLOCCULATION AND THYMOL TURBIDITY TESTS IN PATIENTS WITH EXPERIMENTALLY INDUCED INFECTIOUS HEPATITIS. | 1946 | J. Clin. Invest. | pmid:16695379 |
| Saifer A | A METHOD FOR THE QUANTITATIVE DETERMINATION OF THE CEPHALIN-CHOLESTEROL FLOCCULATION REACTION. | 1948 | J. Clin. Invest. | pmid:16695596 |