| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Willumeit R et al. | Structural rearrangement of model membranes by the peptide antibiotic NK-2. | 2005 | Biochim. Biophys. Acta | pmid:15893515 |
| Hullin-Matsuda F et al. | Probing phosphoethanolamine-containing lipids in membranes with duramycin/cinnamycin and aegerolysin proteins. | 2016 | Biochimie | pmid:27693589 |
| Coulon D et al. | Occurrence, biosynthesis and functions of N-acylphosphatidylethanolamines (NAPE): not just precursors of N-acylethanolamines (NAE). | 2012 | Biochimie | pmid:21575672 |
| Point V et al. | Effects of the propeptide of group X secreted phospholipase A(2) on substrate specificity and interfacial activity on phospholipid monolayers. | 2013 | Biochimie | pmid:22967966 |
| Biswas S et al. | Development of the novel PEG-PE-based polymer for the reversible attachment of specific ligands to liposomes: synthesis and in vitro characterization. | 2011 | Bioconjug. Chem. | pmid:21870873 |
| Andrews CD et al. | Conjugation of lipid and CpG-containing oligonucleotide yields an efficient method for liposome incorporation. | 2011 | Bioconjug. Chem. | pmid:21612239 |
| Sawant RM et al. | "SMART" drug delivery systems: double-targeted pH-responsive pharmaceutical nanocarriers. | 2006 Jul-Aug | Bioconjug. Chem. | pmid:16848401 |
| Shafiq-ur-Rehman | Effect of lead on lipid peroxidation, phospholipids composition, and methylation in erythrocyte of human. | 2013 | Biol Trace Elem Res | pmid:23846836 |
| Moon TC et al. | Ochnaflavone, naturally occurring biflavonoid, inhibits phospholipase A2 dependent phosphatidylethanolamine degradation in a CCl4-induced rat liver microsome. | 2006 | Biol. Pharm. Bull. | pmid:17142963 |
| Joshi N et al. | Carboxymethyl-chitosan-tethered lipid vesicles: hybrid nanoblanket for oral delivery of paclitaxel. | 2013 | Biomacromolecules | pmid:23721348 |
| Mitianina VA et al. | [Erythrocyte lipid composition at different stages of type 1 diabetes in children]. | 2012 Jan-Feb | Biomed Khim | pmid:22642156 |
| Balkina AS et al. | [Liposomal formulations of protein proteinase inhibitors: preparation and specific activity]. | 2008 Sep-Oct | Biomed Khim | pmid:19105398 |
| Symonette CJ et al. | Hyaluronan-phosphatidylethanolamine polymers form pericellular coats on keratinocytes and promote basal keratinocyte proliferation. | 2014 | Biomed Res Int | pmid:25276814 |
| Le MT et al. | Hg2+ and Cd2+ interact differently with biomimetic erythrocyte membranes. | 2009 | Biometals | pmid:18850280 |
| Schober C et al. | Lysophosphatidylethanolamine is - in contrast to - choline - generated under in vivo conditions exclusively by phospholipase A2 but not by hypochlorous acid. | 2009 | Bioorg. Chem. | pmid:19818468 |
| Yang A et al. | Semisynthesis of autophagy protein LC3 conjugates. | 2017 | Bioorg. Med. Chem. | pmid:28583805 |
| Merino-Montero S et al. | Effects of lactose permease of Escherichia coli on the anisotropy and electrostatic surface potential of liposomes. | 2006 | Biophys. Chem. | pmid:16242835 |
| Kreutzberger AJB et al. | Asymmetric Phosphatidylethanolamine Distribution Controls Fusion Pore Lifetime and Probability. | 2017 | Biophys. J. | pmid:29037600 |
| Liu F et al. | Effect of variations in the structure of a polyleucine-based alpha-helical transmembrane peptide on its interaction with phosphatidylethanolamine Bilayers. | 2004 | Biophys. J. | pmid:15454444 |
| Alves ID et al. | Phosphatidylethanolamine enhances rhodopsin photoactivation and transducin binding in a solid supported lipid bilayer as determined using plasmon-waveguide resonance spectroscopy. | 2005 | Biophys. J. | pmid:15501933 |