| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Thukral L et al. | The Molecular Mechanism Underlying Recruitment and Insertion of Lipid-Anchored LC3 Protein into Membranes. | 2015 | Biophys. J. | pmid:26588566 |
| Matyjaszkiewicz A et al. | Subconductance gating and voltage sensitivity of sarcoplasmic reticulum K(+) channels: a modeling approach. | 2015 | Biophys. J. | pmid:26200862 |
| Mead FC and Williams AJ | Electrostatic mechanisms underlie neomycin block of the cardiac ryanodine receptor channel (RyR2). | 2004 | Biophys. J. | pmid:15361409 |
| Alvis SJ et al. | Interactions of anionic phospholipids and phosphatidylethanolamine with the potassium channel KcsA. | 2003 | Biophys. J. | pmid:14645072 |
| Liu F et al. | Effect of variations in the structure of a polyleucine-based alpha-helical transmembrane peptide on its interaction with phosphatidylethanolamine Bilayers. | 2004 | Biophys. J. | pmid:15454444 |
| Ilgü H et al. | Variation of the detergent-binding capacity and phospholipid content of membrane proteins when purified in different detergents. | 2014 | Biophys. J. | pmid:24739165 |
| Polozov IV and Gawrisch K | Domains in binary SOPC/POPE lipid mixtures studied by pulsed field gradient 1H MAS NMR. | 2004 | Biophys. J. | pmid:15345553 |
| Murzyn K et al. | Phosphatidylethanolamine-phosphatidylglycerol bilayer as a model of the inner bacterial membrane. | 2005 | Biophys. J. | pmid:15556990 |
| Leventis R and Silvius JR | Quantitative experimental assessment of macromolecular crowding effects at membrane surfaces. | 2010 | Biophys. J. | pmid:20923646 |
| Shaikh SR et al. | Oleic and docosahexaenoic acid differentially phase separate from lipid raft molecules: a comparative NMR, DSC, AFM, and detergent extraction study. | 2004 | Biophys. J. | pmid:15345554 |
| Carmieli R et al. | Utilizing ESEEM spectroscopy to locate the position of specific regions of membrane-active peptides within model membranes. | 2006 | Biophys. J. | pmid:16258052 |
| Hamai C et al. | Effect of average phospholipid curvature on supported bilayer formation on glass by vesicle fusion. | 2006 | Biophys. J. | pmid:16299084 |
| Lins L et al. | "De novo" design of peptides with specific lipid-binding properties. | 2006 | Biophys. J. | pmid:16275638 |
| Maniti O et al. | Mitochondrial creatine kinase binding to phospholipid monolayers induces cardiolipin segregation. | 2009 | Biophys. J. | pmid:19289067 |
| Garcia-Manyes S et al. | Effect of ion-binding and chemical phospholipid structure on the nanomechanics of lipid bilayers studied by force spectroscopy. | 2005 | Biophys. J. | pmid:15980180 |
| Therrien A and Lafleur M | Melittin-Induced Lipid Extraction Modulated by the Methylation Level of Phosphatidylcholine Headgroups. | 2016 | Biophys. J. | pmid:26789763 |
| Deng L et al. | Construction of a yeast strain with regulatable phospholipid synthesis for analysis of the uptake and metabolism of phosphatidylethanolamine with short acyl chains. | 2007 | Biosci. Biotechnol. Biochem. | pmid:17827694 |
| Ota H et al. | Enzymatic characterization of an amine oxidase from Arthrobacter sp. used to measure phosphatidylethanolamine. | 2008 | Biosci. Biotechnol. Biochem. | pmid:18838796 |
| Sato Y et al. | Transformation of Escherichia coli mediated by natural phospholipids. | 2005 | Biosci. Biotechnol. Biochem. | pmid:15665495 |
| Deng L et al. | Manipulation of major membrane lipid synthesis and its effects on sporulation in Saccharomyces cerevisiae. | 2008 | Biosci. Biotechnol. Biochem. | pmid:18776695 |