| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| DIECKMANN WJ and POTTINGER RE | Serial studies of the cephalin flocculation and thymol turbidity tests in pregnant patients. | 1954 | Am. J. Obstet. Gynecol. | pmid:13207248 |
| CHRISTHILF SM et al. | Liver function during pregnancy and the puerperium, as measured by the cephalin-cholesterol flocculation, the thymol turbidity, and the bromsulfalein tests. | 1950 | Am. J. Obstet. Gynecol. | pmid:15410828 |
| Song H et al. | Coordinated alteration of hepatic gene expression in fatty acid and triglyceride synthesis in LCAT-null mice is associated with altered PUFA metabolism. | 2006 | Am. J. Physiol. Endocrinol. Metab. | pmid:16105858 |
| Godin LM et al. | Spatiotemporal dynamics of actin remodeling and endomembrane trafficking in alveolar epithelial type I cell wound healing. | 2011 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:21216977 |
| Sato Y et al. | Autoantibodies to Factor XII and Kininogen-Dependent Antiphosphatidylethanolamine Antibodies in Patients with Recurrent Pregnancy Loss Augment Platelet Aggregation. | 2015 | Am. J. Reprod. Immunol. | pmid:26011374 |
| Zhu X et al. | Regulation of eosinophil adhesion by lysophosphatidylcholine via a non-store-operated Ca2+ channel. | 2007 | Am. J. Respir. Cell Mol. Biol. | pmid:17218614 |
| Zhao M | Lantibiotics as probes for phosphatidylethanolamine. | 2011 | Amino Acids | pmid:21573677 |
| Shin Y et al. | Clostridium kogasensis sp. nov., a novel member of the genus Clostridium, isolated from soil under a corroded gas pipeline. | 2016 | Anaerobe | pmid:26899448 |
| Zhou L et al. | Determination of phosphatidylethanolamine molecular species in various food matrices by liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS2). | 2012 | Anal Bioanal Chem | pmid:22349329 |
| Abd-Elhadi S et al. | Total α-synuclein levels in human blood cells, CSF, and saliva determined by a lipid-ELISA. | 2016 | Anal Bioanal Chem | pmid:27624766 |
| Buré C et al. | A single run LC-MS/MS method for phospholipidomics. | 2013 | Anal Bioanal Chem | pmid:23064709 |
| Fuchs B et al. | Phosphatidylcholines and -ethanolamines can be easily mistaken in phospholipid mixtures: a negative ion MALDI-TOF MS study with 9-aminoacridine as matrix and egg yolk as selected example. | 2009 | Anal Bioanal Chem | pmid:19690837 |
| Niklas J et al. | High-throughput phospholipid quantitation in mammalian cells using matrix-assisted laser desorption ionization-time of flight mass spectrometry with N-trifluoroacetyl-phosphatidylethanolamine as internal standard. | 2011 | Anal. Biochem. | pmid:21910962 |
| Horie M et al. | Fluorometric immunoassay based on pH-sensitive dye-encapsulating liposomes and gramicidin channels. | 2007 | Anal. Biochem. | pmid:17718997 |
| Richter G et al. | Comparison of the positive and negative ion electrospray ionization and matrix-assisted laser desorption ionization-time-of-flight mass spectra of the reaction products of phosphatidylethanolamines and hypochlorous acid. | 2008 | Anal. Biochem. | pmid:18295587 |
| SPITZER HL and BALINT JA | A rapid quantitative separation of phosphatidyl ethanolamine and phosphatidyl serine by column chromatography. | 1963 | Anal. Biochem. | pmid:13990206 |
| McLaren DG et al. | An ultraperformance liquid chromatography method for the normal-phase separation of lipids. | 2011 | Anal. Biochem. | pmid:21402047 |
| Kamimori H et al. | Studies on the membrane interactions of the cyclotides kalata B1 and kalata B6 on model membrane systems by surface plasmon resonance. | 2005 | Anal. Biochem. | pmid:15649388 |
| Engel H et al. | External surface area determination of lipid vesicles using trinitrobenzene sulfonate and ultraviolet/visible spectrophotometry. | 2013 | Anal. Biochem. | pmid:23933190 |
| Pham HT and Julian RR | Mass shifting and radical delivery with crown ether attachment for separation and analysis of phosphatidylethanolamine lipids. | 2014 | Anal. Chem. | pmid:24548103 |