PE(15:0/20:0)

PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.

Cross Reference

Introduction

To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PE(15:0/20:0)?

PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Cataract D002386 34 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Per page 10 20 50 | Total 42

PubChem Associated disorders and diseases

What pathways are associated with PE(15:0/20:0)

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with PE(15:0/20:0)?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with PE(15:0/20:0)?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PE(15:0/20:0)?

Knock-out

Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).

Cancer Model

Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with PE(15:0/20:0)

Download all related citations
Per page 10 20 50 100 | Total 1374
Authors Title Published Journal PubMed Link
Mysiakina IS and Funtikova NS [Sporangiospore lipids of the mycelial fungus Mucor ramannianus incapable of dimorphic growth]. 2007 Mar-Apr Mikrobiologiia pmid:17583213
Tereshina VM et al. [Biochemical aspects of basidiospore maturation in Agaricus bisporus at various temperatures]. 2007 Sep-Oct Mikrobiologiia pmid:18069322
Luo S et al. Mitochondria: one of the origins for autophagosomal membranes? 2009 Mitochondrion pmid:19398041
Kliman M et al. Structural mass spectrometry analysis of lipid changes in a Drosophila epilepsy model brain. 2010 Mol Biosyst pmid:20379606
Luo R et al. Monitoring Apoptosis of Breast Cancer Xenograft After Paclitaxel Treatment With 99mTc-Labeled Duramycin SPECT/CT. 2016 Mol Imaging pmid:27030401
Schaur RJ Basic aspects of the biochemical reactivity of 4-hydroxynonenal. 2003 Aug-Oct Mol. Aspects Med. pmid:12892992
Weingärtner A et al. Ca2+-activated transbilayer movement of plasma membrane phospholipids in Leishmania donovani during ionomycin or thapsigargin stimulation. 2011 Mol. Biochem. Parasitol. pmid:21684309
Yichoy M et al. Lipidomic analysis reveals that phosphatidylglycerol and phosphatidylethanolamine are newly generated phospholipids in an early-divergent protozoan, Giardia lamblia. 2009 Mol. Biochem. Parasitol. pmid:19393163
Mioka T et al. Phospholipid flippases and Sfk1p, a novel regulator of phospholipid asymmetry, contribute to low permeability of the plasma membrane. 2018 Mol. Biol. Cell pmid:29540528
Sadhu MJ et al. Multiple inputs control sulfur-containing amino acid synthesis in Saccharomyces cerevisiae. 2014 Mol. Biol. Cell pmid:24648496
Boumann HA et al. Depletion of phosphatidylcholine in yeast induces shortening and increased saturation of the lipid acyl chains: evidence for regulation of intrinsic membrane curvature in a eukaryote. 2006 Mol. Biol. Cell pmid:16339082
Alder-Baerens N et al. Loss of P4 ATPases Drs2p and Dnf3p disrupts aminophospholipid transport and asymmetry in yeast post-Golgi secretory vesicles. 2006 Mol. Biol. Cell pmid:16452632
Chalat M et al. C-terminus of the P4-ATPase ATP8A2 functions in protein folding and regulation of phospholipid flippase activity. 2017 Mol. Biol. Cell pmid:27932490
Kihara A and Igarashi Y Cross talk between sphingolipids and glycerophospholipids in the establishment of plasma membrane asymmetry. 2004 Mol. Biol. Cell pmid:15342785
Fujita N et al. An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure. 2008 Mol. Biol. Cell pmid:18768752
Ye C et al. A Metabolic Function for Phospholipid and Histone Methylation. 2017 Mol. Cell pmid:28366644
Ogunbona OB et al. Multitiered and Cooperative Surveillance of Mitochondrial Phosphatidylserine Decarboxylase 1. 2017 Mol. Cell. Biol. pmid:28606933
Suárez-Germà C et al. Modeling FRET to investigate the selectivity of lactose permease of Escherichia coli for lipids. 2014 Mol. Membr. Biol. pmid:24826799
Sawant RR and Torchilin VP Multifunctionality of lipid-core micelles for drug delivery and tumour targeting. 2010 Mol. Membr. Biol. pmid:20929339
Funari SS et al. Farnesol and geranylgeraniol modulate the structural properties of phosphatidylethanolamine model membranes. 2005 Jul-Aug Mol. Membr. Biol. pmid:16154902