| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lee ES et al. | The role of phospholipid methylation in 1-methyl-4-phenyl-pyridinium ion (MPP+)-induced neurotoxicity in PC12 cells. | 2005 | Neurotoxicology | pmid:15950286 |
| Lee SC et al. | In vivo MRS markers of response to CHOP chemotherapy in the WSU-DLCL2 human diffuse large B-cell lymphoma xenograft. | 2008 | NMR Biomed | pmid:18384181 |
| Audi S et al. | Understanding the in vivo uptake kinetics of a phosphatidylethanolamine-binding agent (99m)Tc-Duramycin. | 2012 | Nucl. Med. Biol. | pmid:22534031 |
| Handayani D et al. | A high-dose Shiitake mushroom increases hepatic accumulation of triacylglycerol in rats fed a high-fat diet: underlying mechanism. | 2014 | Nutrients | pmid:24566434 |
| Devlin AM et al. | Developmental Outcomes at 24 Months of Age in Toddlers Supplemented with Arachidonic Acid and Docosahexaenoic Acid: Results of a Double Blind Randomized, Controlled Trial. | 2017 | Nutrients | pmid:28878181 |
| Turner KM et al. | Changes in Lipids and Inflammatory Markers after Consuming Diets High in Red Meat or Dairy for Four Weeks. | 2017 | Nutrients | pmid:28817063 |
| Billeaud C et al. | Effects on Fatty Acid Metabolism of a New Powdered Human Milk Fortifier Containing Medium-Chain Triacylglycerols and Docosahexaenoic Acid in Preterm Infants. | 2018 | Nutrients | pmid:29843467 |
| Sanchez-Alvarez M et al. | Cell cycle progression is an essential regulatory component of phospholipid metabolism and membrane homeostasis. | 2015 | Open Biol | pmid:26333836 |
| Jernigan Jr HM et al. | Effects of cataractogenesis on the CDP-choline pathway: increased phospholipid synthesis in lenses from galactosemic rats and 13/N guinea pigs. | 2005 Jan-Feb | Ophthalmic Res. | pmid:15604593 |
| Vabbilisetty P and Sun XL | Liposome surface functionalization based on different anchoring lipids via Staudinger ligation. | 2014 | Org. Biomol. Chem. | pmid:24413731 |
| Patel D and Witt SN | Ethanolamine and Phosphatidylethanolamine: Partners in Health and Disease. | 2017 | Oxid Med Cell Longev | pmid:28785375 |
| Houston KM et al. | Does Litomosoides sigmodontis synthesize dimethylethanolamine from choline? | 2008 | Parasitology | pmid:17892618 |
| Richmond GS et al. | Lipidomic analysis of bloodstream and procyclic form Trypanosoma brucei. | 2010 | Parasitology | pmid:20602846 |
| Carey AN et al. | Hepatic MDR3 expression impacts lipid homeostasis and susceptibility to inflammatory bile duct obstruction in neonates. | 2017 | Pediatr. Res. | pmid:28355206 |
| Jing F et al. | Dual ligands modified double targeted nano-system for liver targeted gene delivery. | 2013 | Pharm Biol | pmid:23527957 |
| Graessler J et al. | Urinary Lipidomics: evidence for multiple sources and sexual dimorphism in healthy individuals. | 2018 | Pharmacogenomics J. | pmid:28607507 |
| Rahman IA et al. | New players in the fatty acyl ethanolamide metabolism. | 2014 | Pharmacol. Res. | pmid:24747663 |
| Wei F et al. | Assembly and relaxation behaviours of phosphatidylethanolamine monolayers investigated by polarization and frequency resolved SFG-VS. | 2015 | Phys Chem Chem Phys | pmid:26349673 |
| Dura M et al. | Kinetics of cardiac RyR channel gating studied at high temporal resolution. | 2003 | Physiol Res | pmid:14535832 |
| Rezanka T et al. | Very-long-chain iso and anteiso branched fatty acids in N-acylphosphatidylethanolamines from a natural cyanobacterial mat of Calothrix sp. | 2009 | Phytochemistry | pmid:19272619 |