PE(15:0/20:0)

PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.

Cross Reference

Introduction

To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with PE(15:0/20:0)?

PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Fatty Liver D005234 48 associated lipids
Cataract D002386 34 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Per page 10 20 50 | Total 42

PubChem Associated disorders and diseases

What pathways are associated with PE(15:0/20:0)

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with PE(15:0/20:0)?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with PE(15:0/20:0)?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with PE(15:0/20:0)?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with PE(15:0/20:0)?

Knock-out

Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).

Cancer Model

Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with PE(15:0/20:0)

Download all related citations
Per page 10 20 50 100 | Total 1374
Authors Title Published Journal PubMed Link
Kurczy ME et al. Composition based strategies for controlling radii in lipid nanotubes. 2014 PLoS ONE pmid:24392077
Ciesielski F et al. Receptor-independent interaction of bacterial lipopolysaccharide with lipid and lymphocyte membranes; the role of cholesterol. 2012 PLoS ONE pmid:22685597
Patel N et al. A novel three serum phospholipid panel differentiates normal individuals from those with prostate cancer. 2014 PLoS ONE pmid:24603597
Lin C et al. Lipid content and composition of oocytes from five coral species: potential implications for future cryopreservation efforts. 2013 PLoS ONE pmid:23469074
Maniti O et al. Distinct behaviour of the homeodomain derived cell penetrating peptide penetratin in interaction with different phospholipids. 2010 PLoS ONE pmid:21209890
Dixit AK and Jayabaskaran C Phospholipid mediated activation of calcium dependent protein kinase 1 (CaCDPK1) from chickpea: a new paradigm of regulation. 2012 PLoS ONE pmid:23284721
Bartelds R et al. Niosomes, an alternative for liposomal delivery. 2018 PLoS ONE pmid:29649223
Costa JA et al. Wicking: a rapid method for manually inserting ion channels into planar lipid bilayers. 2013 PLoS ONE pmid:23717384
Gao W et al. E1-like activating enzyme Atg7 is preferentially sequestered into p62 aggregates via its interaction with LC3-I. 2013 PLoS ONE pmid:24023838
Wallner S et al. Phosphatidylcholine and phosphatidylethanolamine plasmalogens in lipid loaded human macrophages. 2018 PLoS ONE pmid:30308051
Hirata E et al. Atg4 plays an important role in efficient expansion of autophagic isolation membranes by cleaving lipidated Atg8 in Saccharomyces cerevisiae. 2017 PLoS ONE pmid:28704456
Giles C et al. The Effects of Long-Term Saturated Fat Enriched Diets on the Brain Lipidome. 2016 PLoS ONE pmid:27907021
Urano H et al. Novel Anti-Adhesive CMC-PE Hydrogel Significantly Enhanced Morphological and Physiological Recovery after Surgical Decompression in an Animal Model of Entrapment Neuropathy. 2016 PLoS ONE pmid:27741280
Wang S et al. Chemical Compensation of Mitochondrial Phospholipid Depletion in Yeast and Animal Models of Parkinson's Disease. 2016 PLoS ONE pmid:27736935
Sengupta T and Manoj N Phosphatidylserine and Phosphatidylethanolamine Bind to Protein Z Cooperatively and with Equal Affinity. 2016 PLoS ONE pmid:27584039
Yabas M et al. ATP11C Facilitates Phospholipid Translocation across the Plasma Membrane of All Leukocytes. 2016 PLoS ONE pmid:26799398
Wolny M et al. Key amino acid residues of ankyrin-sensitive phosphatidylethanolamine/phosphatidylcholine-lipid binding site of βI-spectrin. 2011 PLoS ONE pmid:21738695
Raghava S et al. The SV40 late protein VP4 is a viroporin that forms pores to disrupt membranes for viral release. 2011 PLoS Pathog. pmid:21738474
Kolomytseva MP et al. [Heterogeneity of Rhodococcus opacus 1CP as a response to stress induced by chlorophenols]. 2005 Sep-Oct Prikl. Biokhim. Mikrobiol. pmid:16240653
Supattapone S Phosphatidylethanolamine as a prion cofactor: potential implications for disease pathogenesis. 2012 Nov-Dec Prion pmid:22895101