| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lupus Erythematosus, Systemic | D008180 | 43 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Fatty Liver | D005234 | 48 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
PE(15:0/20:0)
PE(15:0/20:0) is a lipid of Glycerophospholipids (GP) class. Pe(15:0/20:0) is associated with abnormalities such as Exanthema, Infection, Painful Bladder Syndrome, Obesity and Fatty Liver. The involved functions are known as conjugation, Transcription, Genetic, Sinking, Autophagy and Protein Biosynthesis. Pe(15:0/20:0) often locates in membrane fraction, soluble, Membrane, Body tissue and Tissue membrane. The associated genes with PE(15:0/20:0) are GABARAPL2 gene, ATG10 gene, ATG12 gene, SLC33A1 gene and GABARAP gene. The related lipids are Liposomes, Lipopolysaccharides, Phosphatidylserines, Membrane Lipids and Cardiolipins. The related experimental models are Knock-out and Cancer Model.
Cross Reference
Introduction
To understand associated biological information of PE(15:0/20:0), we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with PE(15:0/20:0)?
PE(15:0/20:0) is suspected in Infection, CONE-ROD DYSTROPHY 1 (disorder), Diabetes, Obesity, Malaria, Atherosclerosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with PE(15:0/20:0)
PubChem Associated disorders and diseases
What pathways are associated with PE(15:0/20:0)
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with PE(15:0/20:0)?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with PE(15:0/20:0)?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with PE(15:0/20:0)?
Knock-out
Knock-out are used in the study 'Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.' (Hörl G et al., 2011) and Knock-out are used in the study 'An Atg4B mutant hampers the lipidation of LC3 paralogues and causes defects in autophagosome closure.' (Fujita N et al., 2008).
Cancer Model
Cancer Model are used in the study 'Improving penetration in tumors with nanoassemblies of phospholipids and doxorubicin.' (Tang N et al., 2007).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with PE(15:0/20:0)
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| MartÃn-Acebes MA et al. | Lipids and flaviviruses, present and future perspectives for the control of dengue, Zika, and West Nile viruses. | 2016 | Prog. Lipid Res. | pmid:27702593 |
| Daak AA et al. | Docosahexaenoic and eicosapentaenoic acid supplementation does not exacerbate oxidative stress or intravascular haemolysis in homozygous sickle cell patients. | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:24095588 |
| Lamaziere A et al. | Differential distribution of DHA-phospholipids in rat brain after feeding: A lipidomic approach. | 2011 Jan-Feb | Prostaglandins Leukot. Essent. Fatty Acids | pmid:21109411 |
| Riedel S et al. | Differential modulation of the lipid metabolism as a model for cellular resistance to fumonisin B1-induced cytotoxic effects in vitro. | 2016 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:27269712 |
| Gramer G et al. | Long-chain polyunsaturated fatty acid status in children, adolescents and adults with phenylketonuria. | 2016 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:27269713 |
| Laugero KD et al. | Plasma omega 3 polyunsaturated fatty acid status and monounsaturated fatty acids are altered by chronic social stress and predict endocrine responses to acute stress in titi monkeys. | 2011 Mar-Apr | Prostaglandins Leukot. Essent. Fatty Acids | pmid:21211954 |
| Vicente EF et al. | N-terminal microdomain peptide from human dihydroorotate dehydrogenase: structure and model membrane interactions. | 2015 | Protein Pept. Lett. | pmid:24810226 |
| Sa'adedin F and Bradshaw JP | A differential scanning calorimetry study of the effects and interactions of antimicrobial peptide LS3 on phosphatidylethanolamine bilayers. | 2010 | Protein Pept. Lett. | pmid:20673229 |
| Dennison SR et al. | A study on the importance of phenylalanine for aurein functionality. | 2009 | Protein Pept. Lett. | pmid:20001908 |
| Lemkul JA and Bevan DR | Lipid composition influences the release of Alzheimer's amyloid β-peptide from membranes. | 2011 | Protein Sci. | pmid:21692120 |
| Grossfield A et al. | Convergence of molecular dynamics simulations of membrane proteins. | 2007 | Proteins | pmid:17243153 |
| Fleming E et al. | Effect of lipid composition on buforin II structure and membrane entry. | 2008 | Proteins | pmid:18452210 |
| Kaddurah-Daouk R et al. | Impaired plasmalogens in patients with schizophrenia. | 2012 | Psychiatry Res | pmid:22513041 |
| Nuss P et al. | Abnormal transbilayer distribution of phospholipids in red blood cell membranes in schizophrenia. | 2009 | Psychiatry Res | pmid:19646766 |
| POOLE JC and ROBINSON DS | Further observations on the effects of ethanolamine phosphatide on plasma coagulation. | 1956 | Q J Exp Physiol Cogn Med Sci | pmid:13485345 |
| ROBINSON DS and POOLE JC | The similar effect of chylomicra and ethanolamine phosphatide on the generation of thrombin during coagulation. | 1956 | Q J Exp Physiol Cogn Med Sci | pmid:13485325 |
| Moe MK et al. | Vicinal hydroxylation of unsaturated fatty acids for structural characterization of intact neutral phospholipids by negative electrospray ionization tandem quadrupole mass spectrometry. | 2004 | Rapid Commun. Mass Spectrom. | pmid:15317043 |
| Svensson E et al. | Compound-specific stable isotope analysis of nitrogen-containing intact polar lipids. | 2015 | Rapid Commun. Mass Spectrom. | pmid:26522319 |
| Naik SR et al. | Liposomes as potential carrier system for targeted delivery of polyene antibiotics. | 2013 | Recent Pat Inflamm Allergy Drug Discov | pmid:23745986 |
| Aldrovandi M et al. | DioxolaneA3-phosphatidylethanolamines are generated by human platelets and stimulate neutrophil integrin expression. | 2017 | Redox Biol | pmid:28160743 |