2-ETHYLHEXANOIC ACID is a lipid of Fatty Acyls (FA) class. The involved functions are known as Steroid biosynthesis, cholesterol metabolic process, cholesterol transport, Cell Proliferation and progesterone biosynthetic process. 2-ethylhexanoic acid often locates in Organelles, Tissue membrane, Mitochondria, Mitochondrial Membranes and Cytoplasm. The associated genes with 2-ETHYLHEXANOIC ACID are steroidogenic acute regulatory protein and SLC27A1 gene. The related lipids are 2-ethylhexanoic acid, Steroids, Hexanols and (22R)-22-hydroxycholesterol.
To understand associated biological information of 2-ETHYLHEXANOIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with 2-ETHYLHEXANOIC ACID
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Acne Vulgaris | D000152 | 35 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Hydrocephalus | D006849 | 6 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Spinal Dysraphism | D016135 | 1 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kratz LE and Albert JS | 2-Ethylhexanoic acid, found in common plasticizers, leads to an artificial increase in C8 acylcarnitine levels in two neonates treated with extracorporeal membrane oxygenation (ECMO). | 2016 | Clin. Chim. Acta | pmid:27475980 |
| Reddy YS et al. | Study on Synthesis, Characterization and Antiproliferative Activity of Novel Diisopropylphenyl Esters of Selected Fatty Acids. | 2016 | J Oleo Sci | pmid:26666272 |
| Petit A et al. | Modulating rheological and degradation properties of temperature-responsive gelling systems composed of blends of PCLA-PEG-PCLA triblock copolymers and their fully hexanoyl-capped derivatives. | 2012 | Acta Biomater | pmid:22877819 |
| Park HH et al. | Facile size-tunable fabrication of functional tin dioxide nanostructures by multiple size reduction lithography. | 2012 | ACS Appl Mater Interfaces | pmid:22476795 |
| Widjaja LK et al. | Triblock copolymers of ε-caprolactone, trimethylene carbonate, and L-lactide: effects of using random copolymer as hard-block. | 2012 | J Mech Behav Biomed Mater | pmid:22301176 |
| Shah M et al. | Amorphous amphiphilic P(3HV-co-4HB)-b-mPEG block copolymer synthesized from bacterial copolyester via melt transesterification: nanoparticle preparation, cisplatin-loading for cancer therapy and in vitro evaluation. | 2012 | Eur J Pharm Biopharm | pmid:22178562 |
| Feng R et al. | Preparation and in vivo pharmacokinetics of curcumin-loaded PCL-PEG-PCL triblock copolymeric nanoparticles. | 2012 | Int J Nanomedicine | pmid:22888245 |
| Cheng L et al. | Effect of amorphous calcium phosphate and silver nanocomposites on dental plaque microcosm biofilms. | 2012 | J. Biomed. Mater. Res. Part B Appl. Biomater. | pmid:22566464 |
| Cheng L et al. | Antibacterial amorphous calcium phosphate nanocomposites with a quaternary ammonium dimethacrylate and silver nanoparticles. | 2012 | Dent Mater | pmid:22305716 |
| Ghassemi AH et al. | Controlled release of octreotide and assessment of peptide acylation from poly(D,L-lactide-co-hydroxymethyl glycolide) compared to PLGA microspheres. | 2012 | Pharm. Res. | pmid:21744173 |
| Molloi S et al. | Estimation of coronary artery hyperemic blood flow based on arterial lumen volume using angiographic images. | 2012 | Int J Cardiovasc Imaging | pmid:21213052 |
| Piché CD et al. | Effects of di-(2-ethylhexyl) phthalate and four of its metabolites on steroidogenesis in MA-10 cells. | 2012 | Ecotoxicol. Environ. Saf. | pmid:22236953 |
| Wang HJ et al. | [Chemical constituents from the fruits of Kadsura marmorata]. | 2012 | Zhong Yao Cai | pmid:22876677 |
| Hirschmann J et al. | Concept of a thin film memory transistor based on ZnO nanoparticles insulated by a ligand shell. | 2012 | Nanoscale | pmid:22159764 |
| Akbarzadeh A et al. | Preparation and in vitro evaluation of doxorubicin-loaded Fe₃O₄ magnetic nanoparticles modified with biocompatible copolymers. | 2012 | Int J Nanomedicine | pmid:22334781 |
| Walser T et al. | Prospective environmental life cycle assessment of nanosilver T-shirts. | 2011 | Environ. Sci. Technol. | pmid:21506582 |
| Shah M et al. | Synthesis and characterization of PHV-block-mPEG diblock copolymer and its formation of amphiphilic nanoparticles for drug delivery. | 2011 | J Nanosci Nanotechnol | pmid:22121594 |
| de Oliveira RJ et al. | Photoreactive surfactants: a facile and clean route to oxide and metal nanoparticles in reverse micelles. | 2011 | Langmuir | pmid:21739956 |
| Hu B et al. | Polycarbonate microspheres containing mitomycin C and magnetic powders as potential hepatic carcinoma therapeutics. | 2011 | Colloids Surf B Biointerfaces | pmid:21392948 |
| Pham TT et al. | Effect of ultrasonication and Fenton oxidation on biodegradation of bis(2-ethylhexyl) phthalate (DEHP) in wastewater sludge. | 2011 | Chemosphere | pmid:21094970 |
| Cheng L et al. | Developing a highly stable PLGA-mPEG nanoparticle loaded with cisplatin for chemotherapy of ovarian cancer. | 2011 | PLoS ONE | pmid:21966528 |
| Petersen H et al. | Pharmacokinetic and technical comparison of Sandostatin® LAR® and other formulations of long-acting octreotide. | 2011 | BMC Res Notes | pmid:21906300 |
| Gaudin R et al. | Biological monitoring of exposure to di(2-ethylhexyl) phthalate in six French factories: a field study. | 2011 | Int Arch Occup Environ Health | pmid:20803214 |
| Carta F et al. | Carbonic anhydrase inhibitors. Inhibition of the β-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with branched aliphatic/aromatic carboxylates and their derivatives. | 2011 | Bioorg. Med. Chem. Lett. | pmid:21402476 |
| Tyson T et al. | Functional and highly porous scaffolds for biomedical applications. | 2011 | Macromol Biosci | pmid:21842506 |
| Cahill JL and Andersen KE | Occupational cobalt-allergic contact dermatitis resulting from polyester resin. | 2010 | Contact Derm. | pmid:20946461 |
| Morakul S et al. | Comprehensive study of the evolution of gas-liquid partitioning of aroma compounds during wine alcoholic fermentation. | 2010 | J. Agric. Food Chem. | pmid:20735035 |
| Poovarodom S et al. | Effect of alkyl functionalization on charging of colloidal silica in apolar media. | 2010 | J Colloid Interface Sci | pmid:20728088 |
| Ercolini D et al. | Different molecular types of Pseudomonas fragi have the same overall behaviour as meat spoilers. | 2010 | Int. J. Food Microbiol. | pmid:20627208 |
| Teleki A et al. | Continuous surface functionalization of flame-made TiO2 nanoparticles. | 2010 | Langmuir | pmid:20192157 |
| Dillon LA et al. | Optimisation of secondary electrospray ionisation (SESI) for the trace determination of gas-phase volatile organic compounds. | 2010 | Analyst | pmid:20098763 |
| O'Bryan G et al. | Stress sensing in polycaprolactone films via an embedded photochromic compound. | 2010 | ACS Appl Mater Interfaces | pmid:20568704 |
| Nikolic L et al. | Novel microwave-assisted synthesis of poly(D,L-lactide): the influence of monomer/initiator molar ratio on the product properties. | 2010 | Sensors (Basel) | pmid:22399924 |
| Krieger J et al. | Brain architecture of the largest living land arthropod, the Giant Robber Crab Birgus latro (Crustacea, Anomura, Coenobitidae): evidence for a prominent central olfactory pathway? | 2010 | Front. Zool. | pmid:20831795 |
| Wolf FK et al. | Poly(glycolide) multi-arm star polymers: Improved solubility via limited arm length. | 2010 | Beilstein J Org Chem | pmid:20703381 |
| Zhang Y et al. | Preparation and evaluation of poly(ethylene glycol)-poly(lactide) micelles as nanocarriers for oral delivery of cyclosporine a. | 2010 | Nanoscale Res Lett | pmid:20671795 |
| Kluger PJ et al. | Electrospun poly(D/L-lactide-co-L-lactide) hybrid matrix: a novel scaffold material for soft tissue engineering. | 2010 | J Mater Sci Mater Med | pmid:20640490 |
| Ghassemi AH et al. | Hydrophilic polyester microspheres: effect of molecular weight and copolymer composition on release of BSA. | 2010 | Pharm. Res. | pmid:20602152 |
| Feige JN et al. | The pollutant diethylhexyl phthalate regulates hepatic energy metabolism via species-specific PPARalpha-dependent mechanisms. | 2010 | Environ. Health Perspect. | pmid:20123618 |
| Matsumura K et al. | Urinary volatile compounds as biomarkers for lung cancer: a proof of principle study using odor signatures in mouse models of lung cancer. | 2010 | PLoS ONE | pmid:20111698 |
| Reinhard J et al. | Honeybees learn odour mixtures via a selection of key odorants. | 2010 | PLoS ONE | pmid:20161714 |
| Zhang Q et al. | Tuning the shape and thermoelectric property of PbTe nanocrystals by bismuth doping. | 2010 | Nanoscale | pmid:20648359 |
| Di Tommaso C et al. | Investigations on the lyophilisation of MPEG-hexPLA micelle based pharmaceutical formulations. | 2010 | Eur J Pharm Sci | pmid:20184955 |
| Chan-Seng D et al. | Aliphatic polyester terpolymers for stent coating and drug elution: effect of polymer composition on drug solubility and release. | 2009 | Drug Deliv | pmid:19606944 |
| Lowe JR et al. | Oxidized dihydrocarvone as a renewable multifunctional monomer for the synthesis of shape memory polyesters. | 2009 | Biomacromolecules | pmid:19505135 |
| Timbart L et al. | Low viscosity poly(trimethylene carbonate) for localized drug delivery: rheological properties and in vivo degradation. | 2009 | Macromol Biosci | pmid:19253418 |
| McInnes SJ et al. | New biodegradable materials produced by ring opening polymerisation of poly(L-lactide) on porous silicon substrates. | 2009 | J Colloid Interface Sci | pmid:19200556 |
| Habnouni SE et al. | Synthesis and Ring Opening Polymerization of a New Functional Lactone, α-Iodo-ε-caprolactone: A Novel Route to Functionalized Aliphatic Polyesters. | 2009 | Macromol Rapid Commun | pmid:21706593 |
| Alley WM et al. | Model Ziegler-type hydrogenation catalyst precursors, [(1,5-COD)M(mu-O2C8H15)]2 (M = Ir and Rh): synthesis, characterization, and demonstration of catalytic activity en route to identifying the true industrial hydrogenation catalysts. | 2009 | Inorg Chem | pmid:19127998 |
| Chang KY and Lee YD | Ring-opening polymerization of epsilon-caprolactone initiated by the antitumor agent doxifluridine. | 2009 | Acta Biomater | pmid:19101214 |
| Iqbal MS and Akmal MA | A simple method for simultaneous determination of some organic liquids in in-process materials and effluents produced in the manufacture of amoxicillin and ampicillin. | 2009 | Environ Monit Assess | pmid:18386144 |
| Chen X et al. | Preparation and characterization of PEG-modified polyurethane pressure-sensitive adhesives for transdermal drug delivery. | 2009 | Drug Dev Ind Pharm | pmid:19514985 |
| Caricato AP et al. | Nanoparticle thin films for gas sensors prepared by matrix assisted pulsed laser evaporation. | 2009 | Sensors (Basel) | pmid:22574039 |
| Liewhiran C et al. | H(2) Sensing Response of Flame-Spray-Made Ru/SnO(2) Thick Films Fabricated from Spin-Coated Nanoparticles. | 2009 | Sensors (Basel) | pmid:22291549 |
| Li X et al. | Self-assembled polymeric micellar nanoparticles as nanocarriers for poorly soluble anticancer drug ethaselen. | 2009 | Nanoscale Res Lett | pmid:20652138 |
| Darracq G et al. | Absorption and biodegradation of hydrophobic volatile organic compounds: determination of Henry's constants and biodegradation levels. | 2009 | Water Sci. Technol. | pmid:19380996 |
| Ding D et al. | Yeast bioassay for identification of inositol depleting compounds. | 2009 | World J. Biol. Psychiatry | pmid:18979283 |
| Zanor MI et al. | Metabolic characterization of loci affecting sensory attributes in tomato allows an assessment of the influence of the levels of primary metabolites and volatile organic contents. | 2009 | J. Exp. Bot. | pmid:19346240 |
| Torres-Nieto J et al. | Catalytic desulfurization of dibenzothiophene with palladium nanoparticles. | 2008 | Inorg Chem | pmid:18921995 |
| Mespouille L et al. | Novel biodegradable adaptive hydrogels: controlled synthesis and full characterization of the amphiphilic co-networks. | 2008 | Chemistry | pmid:18537206 |
| Yamada T et al. | Intracerebral microinjection of stannous 2-ethylhexanoate affects dopamine turnover in cerebral cortex and locomotor activity in rats. | 2008 | J. Biomed. Mater. Res. Part B Appl. Biomater. | pmid:18506812 |
| Stjerndahl A et al. | Minimization of residual tin in the controlled Sn(II)octoate-catalyzed polymerization of epsilon-caprolactone. | 2008 | J Biomed Mater Res A | pmid:18306295 |
| Khanna A et al. | Molecular modeling studies of poly lactic acid initiation mechanisms. | 2008 | J Mol Model | pmid:18299904 |
| Jayakumar R and Tamura H | Synthesis, characterization and thermal properties of chitin-g-poly(epsilon-caprolactone) copolymers by using chitin gel. | 2008 | Int. J. Biol. Macromol. | pmid:17950453 |
| Barnabé S et al. | Plasticizers and their degradation products in the process streams of a large urban physicochemical sewage treatment plant. | 2008 | Water Res. | pmid:17706266 |
| Ito Y and Nakajima T | PPARalpha- and DEHP-Induced Cancers. | 2008 | PPAR Res | pmid:18769559 |
| Wayengera M et al. | Identification of restriction endonuclease with potential ability to cleave the HSV-2 genome: inherent potential for biosynthetic versus live recombinant microbicides. | 2008 | Theor Biol Med Model | pmid:18687114 |
| Latini G et al. | Peroxisome proliferator-activated receptors as mediators of phthalate-induced effects in the male and female reproductive tract: epidemiological and experimental evidence. | 2008 | PPAR Res | pmid:18288285 |
| Mazarro R et al. | Copolymerization of D,L-lactide and glycolide in supercritical carbon dioxide with zinc octoate as catalyst. | 2008 | J. Biomed. Mater. Res. Part B Appl. Biomater. | pmid:17854066 |
| Gaudin R et al. | Biological monitoring of occupational exposure to di(2-ethylhexyl) phthalate: survey of workers exposed to plastisols. | 2008 | Int Arch Occup Environ Health | pmid:18097680 |
| Kwak J et al. | Genetically-based olfactory signatures persist despite dietary variation. | 2008 | PLoS ONE | pmid:18974891 |
| Kaihara S et al. | Synthesis of poly(L-lactide) and polyglycolide by ring-opening polymerization. | 2007 | Nat Protoc | pmid:18007612 |
| Peterangelo SC et al. | Correlation between rheological properties of zinc carboxylate liquids and molecular structure. | 2007 | J Phys Chem B | pmid:17530877 |
| Yuan W et al. | Syntheses, characterization, and in vitro degradation of ethyl cellulose-graft-poly(epsilon-caprolactone)-block-poly(L-lactide) copolymers by sequential ring-opening polymerization. | 2007 | Biomacromolecules | pmid:17326679 |
| Trimaille T et al. | Poly(hexyl-substituted lactides): novel injectable hydrophobic drug delivery systems. | 2007 | J Biomed Mater Res A | pmid:16958050 |
| Stingel D et al. | Urinary 2-ethyl-3-oxohexanoic acid as major metabolite of orally administered 2-ethylhexanoic acid in human. | 2007 | Mol Nutr Food Res | pmid:17309117 |
| Ezerskis Z et al. | Survey of 2-ethylhexanoic acid in baby food. | 2007 | Food Addit Contam | pmid:17613065 |
| Mishra S et al. | Metal 2-ethylhexanoates and related compounds as useful precursors in materials science. | 2007 | Chem Soc Rev | pmid:18213985 |
| Svechnikova I et al. | The influence of di-(2-ethylhexyl) phthalate on steroidogenesis by the ovarian granulosa cells of immature female rats. | 2007 | J. Endocrinol. | pmid:17761899 |
| Trimaille T et al. | Novel polymeric micelles for hydrophobic drug delivery based on biodegradable poly(hexyl-substituted lactides). | 2006 | Int J Pharm | pmid:16713691 |
| Kaler G et al. | Olfactory mucosa-expressed organic anion transporter, Oat6, manifests high affinity interactions with odorant organic anions. | 2006 | Biochem. Biophys. Res. Commun. | pmid:17094945 |
| Gafni Y et al. | Design of a filamentous polymeric scaffold for in vivo guided angiogenesis. | 2006 | Tissue Eng. | pmid:17518618 |
| Patterson BM et al. | Elemental and molecular characterization of aged polydimethylsiloxane foams. | 2006 | Appl Spectrosc | pmid:17059661 |
| Brethon A et al. | Interplay between lead carboxylate and Ti or Zr isopropoxides in solution routes to perovskites: synthesis, molecular structures and reactivity of single source non-oxo Pb-Zr and Pb-Ti carboxylatoalkoxides supported by 2-ethylhexanoate ligands. | 2006 | Dalton Trans | pmid:16357983 |
| Abraham GA et al. | Bioresorbable poly(ester-ether urethane)s from L-lysine diisocyanate and triblock copolymers with different hydrophilic character. | 2006 | J Biomed Mater Res A | pmid:16317720 |
| Nalli S et al. | Origin of 2-ethylhexanol as a VOC. | 2006 | Environ. Pollut. | pmid:16125828 |
| Nalli S et al. | Interaction of metabolites with R. rhodochrous during the biodegradation of di-ester plasticizers. | 2006 | Chemosphere | pmid:16777176 |
| Xu Y et al. | Effects of di-(2-ethylhexyl)-phthalate and its metabolites on the lipid profiling in rat HRP-1 trophoblast cells. | 2006 | Arch. Toxicol. | pmid:16328440 |
| Gerhardt WW et al. | Functional lactide monomers: methodology and polymerization. | 2006 | Biomacromolecules | pmid:16768392 |
| Odelius K et al. | Elastomeric hydrolyzable porous scaffolds: copolymers of aliphatic polyesters and a polyether-ester. | 2005 Sep-Oct | Biomacromolecules | pmid:16153111 |
| Fan Y et al. | L-Phe end-capped poly(L-lactide) as macroinitiator for the synthesis of poly(L-lactide)-B-poly(L-lysine) block copolymer. | 2005 Nov-Dec | Biomacromolecules | pmid:16283726 |
| Nishino S et al. | Preparation and interfacial properties of a novel biodegradable polymer surfactant: poly(ethylene oxide monooleate-block-DL-lactide). | 2005 | Macromol Biosci | pmid:16245272 |
| Jossen R et al. | Morphology and composition of spray-flame-made yttria-stabilized zirconia nanoparticles. | 2005 | Nanotechnology | pmid:21727483 |
| Liu L et al. | Preparation of chitosan-g-polycaprolactone copolymers through ring-opening polymerization of epsilon-caprolactone onto phthaloyl-protected chitosan. | 2005 | Biopolymers | pmid:15861381 |
| Xu Y et al. | Effects of di-(2-ethylhexyl)-phthalate (DEHP) and its metabolites on fatty acid homeostasis regulating proteins in rat placental HRP-1 trophoblast cells. | 2005 | Toxicol. Sci. | pmid:15647598 |
| Andre M et al. | Ionic liquids as advantageous solvents for headspace gas chromatography of compounds with low vapor pressure. | 2005 | Anal. Chem. | pmid:15649075 |
| Gurvich N et al. | Association of valproate-induced teratogenesis with histone deacetylase inhibition in vivo. | 2005 | FASEB J. | pmid:15901671 |
| Fernandes EG et al. | Bio-based polymeric composites comprising wood flour as filler. | 2004 Jul-Aug | Biomacromolecules | pmid:15244431 |
| Ohta K et al. | Separation and conductimetric detection of C1-C7 aliphatic monocarboxylic acids and C1-C7 aliphatic monoamines on unfunctionized polymethacrylate resin columns. | 2004 | J Chromatogr A | pmid:15250420 |
| Shi R and Burt HM | Amphiphilic dextran-graft-poly(epsilon-caprolactone) films for the controlled release of paclitaxel. | 2004 | Int J Pharm | pmid:15129983 |