2-ETHYLHEXANOIC ACID is a lipid of Fatty Acyls (FA) class. The involved functions are known as Steroid biosynthesis, cholesterol metabolic process, cholesterol transport, Cell Proliferation and progesterone biosynthetic process. 2-ethylhexanoic acid often locates in Organelles, Tissue membrane, Mitochondria, Mitochondrial Membranes and Cytoplasm. The associated genes with 2-ETHYLHEXANOIC ACID are steroidogenic acute regulatory protein and SLC27A1 gene. The related lipids are 2-ethylhexanoic acid, Steroids, Hexanols and (22R)-22-hydroxycholesterol.
To understand associated biological information of 2-ETHYLHEXANOIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with 2-ETHYLHEXANOIC ACID
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Hydrocephalus | D006849 | 6 associated lipids |
| Spinal Dysraphism | D016135 | 1 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wang HJ et al. | [Chemical constituents from the fruits of Kadsura marmorata]. | 2012 | Zhong Yao Cai | pmid:22876677 |
| Deisinger PJ et al. | Metabolism of 2-ethylhexanol administered orally and dermally to the female Fischer 344 rat. | 1994 | Xenobiotica | pmid:8079502 |
| English JC et al. | Metabolism of 2-ethylhexanoic acid administered orally or dermally to the female Fischer 344 rat. | 1998 | Xenobiotica | pmid:9711813 |
| Ding D et al. | Yeast bioassay for identification of inositol depleting compounds. | 2009 | World J. Biol. Psychiatry | pmid:18979283 |
| Darracq G et al. | Absorption and biodegradation of hydrophobic volatile organic compounds: determination of Henry's constants and biodegradation levels. | 2009 | Water Sci. Technol. | pmid:19380996 |
| Barnabé S et al. | Plasticizers and their degradation products in the process streams of a large urban physicochemical sewage treatment plant. | 2008 | Water Res. | pmid:17706266 |
| Horn O et al. | Plasticizer metabolites in the environment. | 2004 | Water Res. | pmid:15350420 |
| Plonait SL et al. | Exposure of newborn infants to di-(2-ethylhexyl)-phthalate and 2-ethylhexanoic acid following exchange transfusion with polyvinylchloride catheters. | 1993 | Transfusion | pmid:8333024 |
| Bui LM et al. | Altered zinc metabolism contributes to the developmental toxicity of 2-ethylhexanoic acid, 2-ethylhexanol and valproic acid. | 1998 | Toxicology | pmid:9585088 |
| Xu Y et al. | Effects of di-(2-ethylhexyl)-phthalate (DEHP) and its metabolites on fatty acid homeostasis regulating proteins in rat placental HRP-1 trophoblast cells. | 2005 | Toxicol. Sci. | pmid:15647598 |