2-ETHYLHEXANOIC ACID is a lipid of Fatty Acyls (FA) class. The involved functions are known as Steroid biosynthesis, cholesterol metabolic process, cholesterol transport, Cell Proliferation and progesterone biosynthetic process. 2-ethylhexanoic acid often locates in Organelles, Tissue membrane, Mitochondria, Mitochondrial Membranes and Cytoplasm. The associated genes with 2-ETHYLHEXANOIC ACID are steroidogenic acute regulatory protein and SLC27A1 gene. The related lipids are 2-ethylhexanoic acid, Steroids, Hexanols and (22R)-22-hydroxycholesterol.
To understand associated biological information of 2-ETHYLHEXANOIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with 2-ETHYLHEXANOIC ACID
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Hydrocephalus | D006849 | 6 associated lipids |
| Spinal Dysraphism | D016135 | 1 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| English JC et al. | Metabolism of 2-ethylhexanoic acid administered orally or dermally to the female Fischer 344 rat. | 1998 | Xenobiotica | pmid:9711813 |
| Juberg DR et al. | 2-Ethylhexanoic acid: subchronic oral toxicity studies in the rat and mouse. | 1998 | Food Chem. Toxicol. | pmid:9662418 |
| Bui LM et al. | Altered zinc metabolism contributes to the developmental toxicity of 2-ethylhexanoic acid, 2-ethylhexanol and valproic acid. | 1998 | Toxicology | pmid:9585088 |
| Ejlertsson J and Svensson BH | Degradation of bis(2-ethylhexyl) phthalate constituents under methanogenic conditions. | 1996-1997 | Biodegradation | pmid:9188196 |
| Sumida K et al. | Inhibition of animal acetyl-coenzyme A carboxylase by 2-(p-chlorophenoxy)-2-methylpropionic acid and 2-ethylhexanoic acid. | 1996 | Chemosphere | pmid:8938993 |
| Pennanen S et al. | CYP enzymes catalyze the formation of a terminal olefin from 2-ethylhexanoic acid in rat and human liver. | 1996 | Hum Exp Toxicol | pmid:8735469 |
| Aberg F et al. | Increases in tissue levels of ubiquinone in association with peroxisome proliferation. | 1996 | Chem. Biol. Interact. | pmid:8620569 |
| Hendrickx AG et al. | Assessment of the developmental toxicity of 2-ethylhexanoic acid in rats and rabbits. | 1993 | Fundam Appl Toxicol | pmid:8449392 |
| Jenke DR et al. | Accumulation model for solutes leaching from polymeric containers. | 1993 Jul-Aug | J Parenter Sci Technol | pmid:8410563 |
| Pennanen S et al. | Effects of 2-ethylhexanoic acid on reproduction and postnatal development in Wistar rats. | 1993 | Fundam Appl Toxicol | pmid:8405783 |