2-ETHYLHEXANOIC ACID

2-ETHYLHEXANOIC ACID is a lipid of Fatty Acyls (FA) class. The involved functions are known as Steroid biosynthesis, cholesterol metabolic process, cholesterol transport, Cell Proliferation and progesterone biosynthetic process. 2-ethylhexanoic acid often locates in Organelles, Tissue membrane, Mitochondria, Mitochondrial Membranes and Cytoplasm. The associated genes with 2-ETHYLHEXANOIC ACID are steroidogenic acute regulatory protein and SLC27A1 gene. The related lipids are 2-ethylhexanoic acid, Steroids, Hexanols and (22R)-22-hydroxycholesterol.

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Introduction

To understand associated biological information of 2-ETHYLHEXANOIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2-ETHYLHEXANOIC ACID?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-ETHYLHEXANOIC ACID

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Body Weight D001835 333 associated lipids
Acne Vulgaris D000152 35 associated lipids
Occupational Diseases D009784 42 associated lipids
Hydrocephalus D006849 6 associated lipids
Spinal Dysraphism D016135 1 associated lipids
Total 6

PubChem Associated disorders and diseases

What pathways are associated with 2-ETHYLHEXANOIC ACID

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2-ETHYLHEXANOIC ACID?

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What functions are associated with 2-ETHYLHEXANOIC ACID?


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What lipids are associated with 2-ETHYLHEXANOIC ACID?

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What genes are associated with 2-ETHYLHEXANOIC ACID?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 2-ETHYLHEXANOIC ACID?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 2-ETHYLHEXANOIC ACID

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Authors Title Published Journal PubMed Link
pmid:
Maloney EK and Waxman DJ trans-Activation of PPARalpha and PPARgamma by structurally diverse environmental chemicals. 1999 Toxicol. Appl. Pharmacol. pmid:10581215
Aulmann W et al. Developmental toxicity of 2-ethylhexyl stearate. 2000 Food Chem. Toxicol. pmid:10685014
Kim SY et al. Poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide)/poly(epsilon-caprolactone) (PCL) amphiphilic block copolymeric nanospheres. II. Thermo-responsive drug release behaviors. 2000 J Control Release pmid:10699293
Cai Q et al. Synthesis and degradation of a tri-component copolymer derived from glycolide, L-lactide, and epsilon-caprolactone. 2000 J Biomater Sci Polym Ed pmid:10841279
Wang N et al. Synthesis, characterization, biodegradation, and drug delivery application of biodegradable lactic/glycolic acid polymers: I. Synthesis and characterization. 2000 J Biomater Sci Polym Ed pmid:10841281
Ural E et al. Poly(D,L-lactide/epsilon-caprolactone)/hydroxyapatite composites. 2000 Biomaterials pmid:10985487
Pennanen SM et al. Effects of 2-ethylhexanoic acid on the production of reactive oxygen species in human polymorphonuclear leukocytes in vitro. 2000 Toxicol. Lett. pmid:11033236
Walker V and Mills GA Urine 4-heptanone: a beta-oxidation product of 2-ethylhexanoic acid from plasticisers. 2001 Clin. Chim. Acta pmid:11282094
Wahl HG et al. Simultaneous analysis of the di(2-ethylhexyl)phthalate metabolites 2-ethylhexanoic acid, 2-ethyl-3-hydroxyhexanoic acid and 2-ethyl-3-oxohexanoic acid in urine by gas chromatography-mass spectrometry. 2001 J. Chromatogr. B Biomed. Sci. Appl. pmid:11486831
French KJ et al. Benign synthesis of 2-ethylhexanoic acid by cytochrome P450cam: enzymatic, crystallographic, and theoretical studies. 2001 Biochemistry pmid:11583152
Rimmer DA et al. Determination of organo-zinc based fungicides in timber treatments employing gas chromatographic analysis with mass selective detection and/or inductively coupled plasma atomic emission spectroscopy. 2001 J Chromatogr A pmid:11587339
Staples CA A review of the environmental fate and aquatic effects of a series of C4 and C8 oxo-process chemicals. 2001 Chemosphere pmid:11592424
French KJ et al. Active site mutations of cytochrome p450cam alter the binding, coupling, and oxidation of the foreign substrates (R)- and (s)-2-ethylhexanol. 2002 Arch. Biochem. Biophys. pmid:11831849
Dillingham EO et al. Biological evaluation of polymers. I. Poly(methyl methacylate). 1975 J. Biomed. Mater. Res. pmid:1184607
Mizutani M et al. Liquid, phenylazide-end-capped copolymers of epsilon-caprolactone and trimethylene carbonate: preparation, photocuring characteristics, and surface layering. Biomacromolecules pmid:12099809
Ravenelle F and Marchessault RH One-step synthesis of amphiphilic diblock copolymers from bacterial poly([R]-3-hydroxybutyric acid). Biomacromolecules pmid:12217053
Norplant update. 1988 Netw Res Triangle Park N C pmid:12280954
Lampen A et al. Teratogenic phthalate esters and metabolites activate the nuclear receptors PPARs and induce differentiation of F9 cells. 2003 Toxicol. Appl. Pharmacol. pmid:12668118
Nallii S et al. Biodegradation of plasticizers by Rhodococcus rhodochrous. 2002 Biodegradation pmid:12688586
Pennanen S et al. The developmental toxicity of 2-ethylhexanoic acid in Wistar rats. 1992 Fundam Appl Toxicol pmid:1426708
Macherey AC et al. Enantioselectivity in the induction of peroxisome proliferation by 2-ethylhexanoic acid. 1992 Chirality pmid:1476857
Kricheldorf HR et al. Telechelic and star-shaped poly(L-lactide)s by means of bismuth(III) acetate as initiator. Biomacromolecules pmid:15003011
Younes HM et al. Synthesis, characterization and in vitro degradation of a biodegradable elastomer. 2004 Biomaterials pmid:15110477
Shi R and Burt HM Amphiphilic dextran-graft-poly(epsilon-caprolactone) films for the controlled release of paclitaxel. 2004 Int J Pharm pmid:15129983
Fernandes EG et al. Bio-based polymeric composites comprising wood flour as filler. 2004 Jul-Aug Biomacromolecules pmid:15244431
Amsden B et al. Synthesis and characterization of thermoset biodegradable elastomers based on star-poly(epsilon-caprolactone-co-D,L-lactide). Biomacromolecules pmid:15244457
Ohta K et al. Separation and conductimetric detection of C1-C7 aliphatic monocarboxylic acids and C1-C7 aliphatic monoamines on unfunctionized polymethacrylate resin columns. 2004 J Chromatogr A pmid:15250420
Labeda DP et al. Enantioselective hydrolysis of butyl 2-ethylhexanoate by a strain of Nocardia corynebacteroides. 2004 Curr. Microbiol. pmid:15297919
Horn O et al. Plasticizer metabolites in the environment. 2004 Water Res. pmid:15350420
Zeng F et al. Synthesis and characterization of biodegradable poly(ethylene glycol)-block-poly(5-benzyloxy-trimethylene carbonate) copolymers for drug delivery. Biomacromolecules pmid:15360292
Elss S et al. Occurrence of 2-ethylhexanoic acid in foods packed in glass jars. 2004 Food Addit Contam pmid:15370833
Collins MD et al. Murine teratology and pharmacokinetics of the enantiomers of sodium 2-ethylhexanoate. 1992 Toxicol. Appl. Pharmacol. pmid:1539163
Xu Y et al. Effects of di-(2-ethylhexyl)-phthalate (DEHP) and its metabolites on fatty acid homeostasis regulating proteins in rat placental HRP-1 trophoblast cells. 2005 Toxicol. Sci. pmid:15647598
Andre M et al. Ionic liquids as advantageous solvents for headspace gas chromatography of compounds with low vapor pressure. 2005 Anal. Chem. pmid:15649075
Liu L et al. Preparation of chitosan-g-polycaprolactone copolymers through ring-opening polymerization of epsilon-caprolactone onto phthaloyl-protected chitosan. 2005 Biopolymers pmid:15861381
Kricheldorf HR and Rost S Copolymerizations of epsilon-caprolactone and glycolide-a comparison of tin(II)octanoate and bismuth(III)subsalicylate as initiators. Biomacromolecules pmid:15877351
Gurvich N et al. Association of valproate-induced teratogenesis with histone deacetylase inhibition in vivo. 2005 FASEB J. pmid:15901671
Keith Y et al. Peroxisome proliferation due to di (2-ethylhexyl) adipate, 2-ethylhexanol and 2-ethylhexanoic acid. 1992 Arch. Toxicol. pmid:1610294
Nalli S et al. Origin of 2-ethylhexanol as a VOC. 2006 Environ. Pollut. pmid:16125828
Odelius K et al. Elastomeric hydrolyzable porous scaffolds: copolymers of aliphatic polyesters and a polyether-ester. 2005 Sep-Oct Biomacromolecules pmid:16153111
Nishino S et al. Preparation and interfacial properties of a novel biodegradable polymer surfactant: poly(ethylene oxide monooleate-block-DL-lactide). 2005 Macromol Biosci pmid:16245272
Fan Y et al. L-Phe end-capped poly(L-lactide) as macroinitiator for the synthesis of poly(L-lactide)-B-poly(L-lysine) block copolymer. 2005 Nov-Dec Biomacromolecules pmid:16283726
Abraham GA et al. Bioresorbable poly(ester-ether urethane)s from L-lysine diisocyanate and triblock copolymers with different hydrophilic character. 2006 J Biomed Mater Res A pmid:16317720
Xu Y et al. Effects of di-(2-ethylhexyl)-phthalate and its metabolites on the lipid profiling in rat HRP-1 trophoblast cells. 2006 Arch. Toxicol. pmid:16328440
Brethon A et al. Interplay between lead carboxylate and Ti or Zr isopropoxides in solution routes to perovskites: synthesis, molecular structures and reactivity of single source non-oxo Pb-Zr and Pb-Ti carboxylatoalkoxides supported by 2-ethylhexanoate ligands. 2006 Dalton Trans pmid:16357983
pmid:16637815
Trimaille T et al. Novel polymeric micelles for hydrophobic drug delivery based on biodegradable poly(hexyl-substituted lactides). 2006 Int J Pharm pmid:16713691
Gerhardt WW et al. Functional lactide monomers: methodology and polymerization. 2006 Biomacromolecules pmid:16768392
Nalli S et al. Interaction of metabolites with R. rhodochrous during the biodegradation of di-ester plasticizers. 2006 Chemosphere pmid:16777176