2-ETHYLHEXANOIC ACID is a lipid of Fatty Acyls (FA) class. The involved functions are known as Steroid biosynthesis, cholesterol metabolic process, cholesterol transport, Cell Proliferation and progesterone biosynthetic process. 2-ethylhexanoic acid often locates in Organelles, Tissue membrane, Mitochondria, Mitochondrial Membranes and Cytoplasm. The associated genes with 2-ETHYLHEXANOIC ACID are steroidogenic acute regulatory protein and SLC27A1 gene. The related lipids are 2-ethylhexanoic acid, Steroids, Hexanols and (22R)-22-hydroxycholesterol.
To understand associated biological information of 2-ETHYLHEXANOIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with 2-ETHYLHEXANOIC ACID
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Hydrocephalus | D006849 | 6 associated lipids |
| Spinal Dysraphism | D016135 | 1 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| French KJ et al. | Active site mutations of cytochrome p450cam alter the binding, coupling, and oxidation of the foreign substrates (R)- and (s)-2-ethylhexanol. | 2002 | Arch. Biochem. Biophys. | pmid:11831849 |
| Barltrop D and Meek F | Effect of particle size on lead absorption from the gut. | 1979 Jul-Aug | Arch. Environ. Health | pmid:475473 |
| Keith Y et al. | Peroxisome proliferation due to di (2-ethylhexyl) adipate, 2-ethylhexanol and 2-ethylhexanoic acid. | 1992 | Arch. Toxicol. | pmid:1610294 |
| Manninen A et al. | 2-Ethylhexanoic acid inhibits urea synthesis and stimulates carnitine acetyltransferase activity in rat liver mitochondria. | 1989 | Arch. Toxicol. | pmid:2730342 |
| Pennanen S et al. | Urinary arginine and ornithine in occupational exposure to 2-ethylhexanoic acid. | 1990 | Arch. Toxicol. | pmid:2403293 |
| Xu Y et al. | Effects of di-(2-ethylhexyl)-phthalate and its metabolites on the lipid profiling in rat HRP-1 trophoblast cells. | 2006 | Arch. Toxicol. | pmid:16328440 |
| Wetterich U and Mutschler E | Quality of cefotaxime sodium preparations. | 1995 | Arzneimittelforschung | pmid:7893275 |
| Wolf FK et al. | Poly(glycolide) multi-arm star polymers: Improved solubility via limited arm length. | 2010 | Beilstein J Org Chem | pmid:20703381 |
| Kaler G et al. | Olfactory mucosa-expressed organic anion transporter, Oat6, manifests high affinity interactions with odorant organic anions. | 2006 | Biochem. Biophys. Res. Commun. | pmid:17094945 |
| De Jongh KS et al. | Kinetic mechanism of sheep liver NADPH-dependent aldehyde reductase. | 1987 | Biochem. J. | pmid:3593233 |