2-ETHYLHEXANOIC ACID is a lipid of Fatty Acyls (FA) class. The involved functions are known as Steroid biosynthesis, cholesterol metabolic process, cholesterol transport, Cell Proliferation and progesterone biosynthetic process. 2-ethylhexanoic acid often locates in Organelles, Tissue membrane, Mitochondria, Mitochondrial Membranes and Cytoplasm. The associated genes with 2-ETHYLHEXANOIC ACID are steroidogenic acute regulatory protein and SLC27A1 gene. The related lipids are 2-ethylhexanoic acid, Steroids, Hexanols and (22R)-22-hydroxycholesterol.
To understand associated biological information of 2-ETHYLHEXANOIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with 2-ETHYLHEXANOIC ACID
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Hydrocephalus | D006849 | 6 associated lipids |
| Spinal Dysraphism | D016135 | 1 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sundberg C et al. | Comparison of the potencies of (+)- and (-)-2-ethylhexanoic acid in causing peroxisome proliferation and related biological effects in mouse liver. | 1994 | Chirality | pmid:8018466 |
| Kratz LE and Albert JS | 2-Ethylhexanoic acid, found in common plasticizers, leads to an artificial increase in C8 acylcarnitine levels in two neonates treated with extracorporeal membrane oxygenation (ECMO). | 2016 | Clin. Chim. Acta | pmid:27475980 |
| Walker V and Mills GA | Urine 4-heptanone: a beta-oxidation product of 2-ethylhexanoic acid from plasticisers. | 2001 | Clin. Chim. Acta | pmid:11282094 |
| Hu B et al. | Polycarbonate microspheres containing mitomycin C and magnetic powders as potential hepatic carcinoma therapeutics. | 2011 | Colloids Surf B Biointerfaces | pmid:21392948 |
| Cahill JL and Andersen KE | Occupational cobalt-allergic contact dermatitis resulting from polyester resin. | 2010 | Contact Derm. | pmid:20946461 |
| Labeda DP et al. | Enantioselective hydrolysis of butyl 2-ethylhexanoate by a strain of Nocardia corynebacteroides. | 2004 | Curr. Microbiol. | pmid:15297919 |
| Brethon A et al. | Interplay between lead carboxylate and Ti or Zr isopropoxides in solution routes to perovskites: synthesis, molecular structures and reactivity of single source non-oxo Pb-Zr and Pb-Ti carboxylatoalkoxides supported by 2-ethylhexanoate ligands. | 2006 | Dalton Trans | pmid:16357983 |
| Cheng L et al. | Antibacterial amorphous calcium phosphate nanocomposites with a quaternary ammonium dimethacrylate and silver nanoparticles. | 2012 | Dent Mater | pmid:22305716 |
| Chan-Seng D et al. | Aliphatic polyester terpolymers for stent coating and drug elution: effect of polymer composition on drug solubility and release. | 2009 | Drug Deliv | pmid:19606944 |
| Chen X et al. | Preparation and characterization of PEG-modified polyurethane pressure-sensitive adhesives for transdermal drug delivery. | 2009 | Drug Dev Ind Pharm | pmid:19514985 |