2-bromohexadecanoic acid is a lipid of Fatty Acyls (FA) class. 2-bromohexadecanoic acid is associated with abnormalities such as Varicosity and Coronavirus Infections. The involved functions are known as Cell Proliferation, Apoptosis, Binding (Molecular Function), Regulation and Biochemical Pathway. 2-bromohexadecanoic acid often locates in Membrane, Cytoplasm, Mitochondria, Cell surface and Extracellular. The associated genes with 2-bromohexadecanoic acid are SLC33A1 gene, GRK6 gene, RBP1 gene, DST gene and FATE1 gene. The related lipids are Palmitates, Fatty Acids, Nonesterified Fatty Acids, Fatty Acids, Unsaturated and Oleates.
To understand associated biological information of 2-bromohexadecanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2-bromohexadecanoic acid is suspected in Varicosity, Coronavirus Infections and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 2-bromohexadecanoic acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Cardiomegaly | D006332 | 31 associated lipids |
| Hyperinsulinism | D006946 | 27 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Shipston MJ | Ion channel regulation by protein palmitoylation. | 2011 | J. Biol. Chem. | pmid:21216969 |
| Galli LM and Burrus LW | Differential palmit(e)oylation of Wnt1 on C93 and S224 residues has overlapping and distinct consequences. | 2011 | PLoS ONE | pmid:22046319 |
| Watson ML et al. | Chronic effects of palmitate overload on nutrient-induced insulin secretion and autocrine signalling in pancreatic MIN6 beta cells. | 2011 | PLoS ONE | pmid:21998735 |
| Roselli F et al. | CDK5 is essential for soluble amyloid β-induced degradation of GKAP and remodeling of the synaptic actin cytoskeleton. | 2011 | PLoS ONE | pmid:21829588 |
| Adams MN et al. | The role of palmitoylation in signalling, cellular trafficking and plasma membrane localization of protease-activated receptor-2. | 2011 | PLoS ONE | pmid:22140500 |
| Yap MC et al. | Rapid and selective detection of fatty acylated proteins using omega-alkynyl-fatty acids and click chemistry. | 2010 | J. Lipid Res. | pmid:20028662 |
| Charych EI et al. | Interplay of palmitoylation and phosphorylation in the trafficking and localization of phosphodiesterase 10A: implications for the treatment of schizophrenia. | 2010 | J. Neurosci. | pmid:20610737 |
| Yao J et al. | Localized fetomaternal hyperglycemia: spatial and kinetic definition by positron emission tomography. | 2010 | PLoS ONE | pmid:20700464 |
| Saleem AN et al. | Mice with alopecia, osteoporosis, and systemic amyloidosis due to mutation in Zdhhc13, a gene coding for palmitoyl acyltransferase. | 2010 | PLoS Genet. | pmid:20548961 |
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| Jeffries O et al. | Palmitoylation of the S0-S1 linker regulates cell surface expression of voltage- and calcium-activated potassium (BK) channels. | 2010 | J. Biol. Chem. | pmid:20693285 |
| Israels SJ and McMillan-Ward EM | Palmitoylation supports the association of tetraspanin CD63 with CD9 and integrin alphaIIbbeta3 in activated platelets. | 2010 | Thromb. Res. | pmid:19640571 |
| Maharjan S et al. | Membrane-initiated estradiol signaling increases tyrosine hydroxylase promoter activity with ER alpha in PC12 cells. | 2010 | J. Neurochem. | pmid:19818101 |
| Guardiola-Serrano F et al. | Palmitoylation of human FasL modulates its cell death-inducing function. | 2010 | Cell Death Dis | pmid:21368861 |
| Tomatis VM et al. | Acyl-protein thioesterase 2 catalyzes the deacylation of peripheral membrane-associated GAP-43. | 2010 | PLoS ONE | pmid:21152083 |
| Paskaleva EE et al. | Palmitic acid analogs exhibit nanomolar binding affinity for the HIV-1 CD4 receptor and nanomolar inhibition of gp120-to-CD4 fusion. | 2010 | PLoS ONE | pmid:20730055 |
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