2-bromohexadecanoic acid is a lipid of Fatty Acyls (FA) class. 2-bromohexadecanoic acid is associated with abnormalities such as Varicosity and Coronavirus Infections. The involved functions are known as Cell Proliferation, Apoptosis, Binding (Molecular Function), Regulation and Biochemical Pathway. 2-bromohexadecanoic acid often locates in Membrane, Cytoplasm, Mitochondria, Cell surface and Extracellular. The associated genes with 2-bromohexadecanoic acid are SLC33A1 gene, GRK6 gene, RBP1 gene, DST gene and FATE1 gene. The related lipids are Palmitates, Fatty Acids, Nonesterified Fatty Acids, Fatty Acids, Unsaturated and Oleates.
To understand associated biological information of 2-bromohexadecanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2-bromohexadecanoic acid is suspected in Varicosity, Coronavirus Infections and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 2-bromohexadecanoic acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Cardiomegaly | D006332 | 31 associated lipids |
| Hyperinsulinism | D006946 | 27 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gaudel C and Grimaldi PA | Metabolic Functions of Peroxisome Proliferator-Activated Receptor beta/delta in Skeletal Muscle. | 2007 | PPAR Res | pmid:17389772 |
| Grimaldi PA et al. | Induction of aP2 gene expression by nonmetabolized long-chain fatty acids. | 1992 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1438299 |
| Kim HS et al. | The Pseudomonas syringae effector AvrRpt2 cleaves its C-terminally acylated target, RIN4, from Arabidopsis membranes to block RPM1 activation. | 2005 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15845764 |
| Tutwiler GF | Effects of phenformin and alpha-bromopalmitate on fatty acid and glucose oxidation in muscle. | 1978 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:653108 |
| Santos JM et al. | The Plasmodium palmitoyl-S-acyl-transferase DHHC2 is essential for ookinete morphogenesis and malaria transmission. | 2015 | Sci Rep | pmid:26526684 |
| Chen X et al. | 2-Bromopalmitate modulates neuronal differentiation through the regulation of histone acetylation. | 2014 | Stem Cell Res | pmid:24434630 |
| Israels SJ and McMillan-Ward EM | Palmitoylation supports the association of tetraspanin CD63 with CD9 and integrin alphaIIbbeta3 in activated platelets. | 2010 | Thromb. Res. | pmid:19640571 |
| Vergarajauregui S and Puertollano R | Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomes. | 2006 | Traffic | pmid:16497227 |
| Heinemann HO et al. | The effect of DL-2-bromopalmitate on the utilization of palmitic acid by rat granular pneumocytes. | 1979 | Virchows Arch B Cell Pathol | pmid:105465 |