2-bromohexadecanoic acid is a lipid of Fatty Acyls (FA) class. 2-bromohexadecanoic acid is associated with abnormalities such as Varicosity and Coronavirus Infections. The involved functions are known as Cell Proliferation, Apoptosis, Binding (Molecular Function), Regulation and Biochemical Pathway. 2-bromohexadecanoic acid often locates in Membrane, Cytoplasm, Mitochondria, Cell surface and Extracellular. The associated genes with 2-bromohexadecanoic acid are SLC33A1 gene, GRK6 gene, RBP1 gene, DST gene and FATE1 gene. The related lipids are Palmitates, Fatty Acids, Nonesterified Fatty Acids, Fatty Acids, Unsaturated and Oleates.
To understand associated biological information of 2-bromohexadecanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2-bromohexadecanoic acid is suspected in Varicosity, Coronavirus Infections and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 2-bromohexadecanoic acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Cardiomegaly | D006332 | 31 associated lipids |
| Hyperinsulinism | D006946 | 27 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fong JC et al. | Differential inhibition of lipolysis by 2-bromopalmitic acid and 4-bromocrotonic acid in 3T3-L1 adipocytes. | 1997 | Biochim. Biophys. Acta | pmid:9022756 |
| Anastasia JV and Conley JP | The role of fatty acid oxidation in the epidermis. | 1977 | J. Invest. Dermatol. | pmid:908843 |
| Evans GL and Denton RM | Regulation of fatty acid synthesis and esterification in rat epididymal adipose tissue: effects of insulin, palmitate and 2-bromopalmitate [proceedings]. | 1977 | Biochem. Soc. Trans. | pmid:923911 |
| Aubert J et al. | Up-regulation of UCP-2 gene expression by PPAR agonists in preadipose and adipose cells. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9299560 |
| Hernanz D et al. | Inhibition of sex pheromone production in female lepidopteran moths by 2-halofatty acids. | 1997 | J. Lipid Res. | pmid:9374121 |
| Granneman J et al. | Member of the peroxisome proliferator-activated receptor family of transcription factors is differentially expressed by oligodendrocytes. | 1998 | J. Neurosci. Res. | pmid:9512000 |
| Darimont C et al. | Differential regulation of intestinal and liver fatty acid-binding proteins in human intestinal cell line (Caco-2): role of collagen. | 1998 | Exp. Cell Res. | pmid:9806794 |
| Ockner RK and Manning JA | Fatty acid binding protein. Role in esterification of absorbed long chain fatty acid in rat intestine. | 1976 | J. Clin. Invest. | pmid:986401 |
| Amatruda JM et al. | [14C]palmitate uptake in isolated rat liver mitochondria: effects of fasting, diabetes mellitus, and inhibitors of carnitine acyltransferase. | 1978 | J. Lipid Res. | pmid:99482 |