2-bromohexadecanoic acid is a lipid of Fatty Acyls (FA) class. 2-bromohexadecanoic acid is associated with abnormalities such as Varicosity and Coronavirus Infections. The involved functions are known as Cell Proliferation, Apoptosis, Binding (Molecular Function), Regulation and Biochemical Pathway. 2-bromohexadecanoic acid often locates in Membrane, Cytoplasm, Mitochondria, Cell surface and Extracellular. The associated genes with 2-bromohexadecanoic acid are SLC33A1 gene, GRK6 gene, RBP1 gene, DST gene and FATE1 gene. The related lipids are Palmitates, Fatty Acids, Nonesterified Fatty Acids, Fatty Acids, Unsaturated and Oleates.
To understand associated biological information of 2-bromohexadecanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2-bromohexadecanoic acid is suspected in Varicosity, Coronavirus Infections and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 2-bromohexadecanoic acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Cardiomegaly | D006332 | 31 associated lipids |
| Hyperinsulinism | D006946 | 27 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Holst D et al. | Nutritional regulation and role of peroxisome proliferator-activated receptor delta in fatty acid catabolism in skeletal muscle. | 2003 | Biochim. Biophys. Acta | pmid:12842194 |
| Dorfleutner A and Ruf W | Regulation of tissue factor cytoplasmic domain phosphorylation by palmitoylation. | 2003 | Blood | pmid:12920028 |
| Grimaldi PA et al. | Induction of aP2 gene expression by nonmetabolized long-chain fatty acids. | 1992 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1438299 |
| Clore JN et al. | Evidence for dissociation of gluconeogenesis stimulated by non-esterified fatty acids and changes in fructose 2,6-bisphosphate in cultured rat hepatocytes. | 1992 | Biochem. J. | pmid:1445259 |
| Kovalenko OV et al. | Evidence for specific tetraspanin homodimers: inhibition of palmitoylation makes cysteine residues available for cross-linking. | 2004 | Biochem. J. | pmid:14556650 |
| Chen HQ et al. | Novel roles for palmitoylation of Ras in IL-1 beta-induced nitric oxide release and caspase 3 activation in insulin-secreting beta cells. | 2003 | Biochem. Pharmacol. | pmid:14563479 |
| Parker SM et al. | Palmitate potentiation of glucose-induced insulin release: a study using 2-bromopalmitate. | 2003 | Metab. Clin. Exp. | pmid:14564691 |
| Kausch C et al. | Skeletal muscle cells from insulin-resistant (non-diabetic) individuals are susceptible to insulin desensitization by palmitate. | 2003 | Horm. Metab. Res. | pmid:14605989 |
| Remizov O et al. | Palmitate-induced Ca2+-signaling in pancreatic beta-cells. | 2003 | Mol. Cell. Endocrinol. | pmid:14654245 |
| Gauthier-Campbell C et al. | Regulation of dendritic branching and filopodia formation in hippocampal neurons by specific acylated protein motifs. | 2004 | Mol. Biol. Cell | pmid:14978216 |