2-chloro-acetic acid

2-chloro-acetic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 1900 references associated with 2-chloro-acetic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 2-chloro-acetic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-chloro-acetic acid

MeSH term MeSH ID Detail
Anemia D000740 21 associated lipids
Bird Diseases D001715 4 associated lipids
Body Weight D001835 333 associated lipids
Brain Edema D001929 20 associated lipids
Burns, Chemical D002057 3 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Solitary Pulmonary Nodule D003074 1 associated lipids
Death, Sudden D003645 12 associated lipids
Eosinophilic Granuloma D004803 1 associated lipids
Factor XIII Deficiency D005177 1 associated lipids
Finger Injuries D005383 1 associated lipids
Granuloma D006099 5 associated lipids
Hand Deformities, Acquired D006227 1 associated lipids
Hemangioendothelioma D006390 1 associated lipids
Hypothermia D007035 19 associated lipids
Infertility, Male D007248 11 associated lipids
Kidney Neoplasms D007680 29 associated lipids
Leukemia D007938 74 associated lipids
Leukemia, Hairy Cell D007943 5 associated lipids
Leukemia, Lymphoid D007945 18 associated lipids
Leukemia, Mast-Cell D007946 1 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Liver Diseases D008107 31 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lymphoma D008223 18 associated lipids
Mastocytosis D008415 5 associated lipids
Mediastinal Neoplasms D008479 2 associated lipids
Molluscum Contagiosum D008976 2 associated lipids
Myeloproliferative Disorders D009196 5 associated lipids
Neoplasms, Multiple Primary D009378 8 associated lipids
Occupational Diseases D009784 42 associated lipids
Orbital Neoplasms D009918 3 associated lipids
Oropharyngeal Neoplasms D009959 2 associated lipids
Pharyngeal Neoplasms D010610 4 associated lipids
Polycythemia D011086 4 associated lipids
Pulmonary Eosinophilia D011657 1 associated lipids
Rhabdomyolysis D012206 9 associated lipids
Sarcoma 180 D012510 21 associated lipids
Spinal Cord Compression D013117 5 associated lipids
Giant Cell Arteritis D013700 1 associated lipids
Trichinellosis D014235 9 associated lipids
Urticaria Pigmentosa D014582 4 associated lipids
Uveal Neoplasms D014604 3 associated lipids
Reperfusion Injury D015427 65 associated lipids
Leukemia, Myeloid, Acute D015470 19 associated lipids
Leukemia, Myelomonocytic, Chronic D015477 1 associated lipids
Leukemia, Myelomonocytic, Acute D015479 6 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Renal Insufficiency D051437 8 associated lipids
Per page 10 20 50 | Total 49

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 2-chloro-acetic acid

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Per page 10 20 50 100 | Total 727
Authors Title Published Journal PubMed Link
Kawase T and Oguro A Granulocyte colony-stimulating factor synergistically augments 1,25-dihydroxyvitamin D3-induced monocytic differentiation in murine bone marrow cell cultures. 2004 Horm. Metab. Res. pmid:15305226
Hanson ML and Solomon KR Haloacetic acids in the aquatic environment. Part II: ecological risk assessment. 2004 Environ. Pollut. pmid:15182971
Lookman R et al. Batch-test study on the dechlorination of 1,1,1-trichloroethane in contaminated aquifer material by zero-valent iron. 2004 J. Contam. Hydrol. pmid:15358490
Ghosh AK and Kim JH Stereoselective chloroacetate aldol reactions: syntheses of acetate aldol equivalents and darzens glycidic esters. 2004 Org. Lett. pmid:15281754
Kim K et al. Change of monochloroacetic acid to biodegradable organic acids by hydrothermal reaction. 2004 J. Hazard. Mater. pmid:15081173
Rodrigues JA et al. Diastereoselective synthesis of cularine alkaloids via enium ions and an easy entry to isoquinolines by aza-Wittig electrocyclic ring closure. 2004 J. Org. Chem. pmid:15104427
Hassoun EA and Kini V Effects of superoxide dismutase and polyclonal tumor necrosis factor-alpha antibodies on chloroacetate-induced cellular death and superoxide anion production by J774.A1 macrophages. 2004 Comp. Biochem. Physiol. C Toxicol. Pharmacol. pmid:15450858
Mezö G et al. Synthesis and structural characterization of bioactive peptide conjugates using thioether linkage approaches. 2004 J. Pept. Sci. pmid:15635622
Plewa MJ et al. Chemical and biological characterization of newly discovered iodoacid drinking water disinfection byproducts. 2004 Environ. Sci. Technol. pmid:15487777
Song JS et al. Genetic organization of the dhlA gene encoding 1,2-dichloroethane dechlorinase from Xanthobacter flavus UE15. 2004 J. Microbiol. pmid:15459646
Toshina Y et al. Hepatic injury and gluconeogenesis after subcutaneous injection of monochloroacetic acid in rats. 2004 Environ Health Prev Med pmid:21432300
Pirson J et al. An unusual cause of burn injury: skin exposure to monochloroacetic acid. 2003 Nov-Dec J Burn Care Rehabil pmid:14610430
Nasr MN and Said SA Novel 3,3a,4,5,6,7-hexahydroindazole and arylthiazolylpyrazoline derivatives as anti-inflammatory agents. 2003 Arch. Pharm. (Weinheim) pmid:14677148
Helaleh MI et al. Vacancy ion-exclusion chromatography of haloacetic acids on a weakly acidic cation-exchange resin. 2003 J Chromatogr A pmid:12830885
Bakeas EB et al. Determination of chloroacetates in atmospheric particulate matter. 2003 Environ. Sci. Technol. pmid:12831014
Peters RJ Chloroacetic acids in European soils and vegetation. 2003 J Environ Monit pmid:12729268
Fahimi IJ et al. Formation of chloroacetic acids from soil, humic acid and phenolic moieties. 2003 Chemosphere pmid:12738276
Wong CS et al. Measurement of 13C/12C of chloroacetic acids by gas chromatography/combustion/isotope ratio mass spectrometry. 2003 Chemosphere pmid:12504128
Senogles-Derham PJ et al. Toxicological aspects of treatment to remove cyanobacterial toxins from drinking water determined using the heterozygous P53 transgenic mouse model. 2003 Toxicon pmid:12875872
Saghir SA and Rozman KK Kinetics of monochloroacetic acid at subtoxic and toxic doses in rats after single oral and dermal administrations. 2003 Toxicol. Sci. pmid:12915718
St-Pierre A et al. Evaluation of the influence of chloroacetic acids on the pharmacokinetics of trihalomethanes in the rat. 2003 J. Toxicol. Environ. Health Part A pmid:14612337
Basharova GR et al. [Occupational risk and evaluation of health damage in workers engaged in organochlorine compound production]. 2003 Med Tr Prom Ekol pmid:14593650
Dote T et al. Systemic effects and skin injury after experimental dermal exposure to monochloroacetic acid. 2003 Toxicol Ind Health pmid:15747777
Ammini CV et al. Pharmacologic or genetic ablation of maleylacetoacetate isomerase increases levels of toxic tyrosine catabolites in rodents. 2003 Biochem. Pharmacol. pmid:14599561
Glossmann JP et al. Extramedullary acute myeloid leukemia (granulocytic sarcoma) with arm paresis, maculopapular exanthema and organ involvement. 2003 Leuk. Lymphoma pmid:14565668
Repp R et al. Phase I clinical trial of the bispecific antibody MDX-H210 (anti-FcgammaRI x anti-HER-2/neu) in combination with Filgrastim (G-CSF) for treatment of advanced breast cancer. 2003 Br. J. Cancer pmid:14676800
Hill KE and Weightman AJ Horizontal transfer of dehalogenase genes on IncP1beta plasmids during bacterial adaptation to degrade alpha-halocarboxylic acids. 2003 FEMS Microbiol. Ecol. pmid:19719596
Jo SK et al. Detection of inflammation following renal ischemia by magnetic resonance imaging. 2003 Kidney Int. pmid:12787394
Demopoulos VJ et al. A facile preparation of 1-(6-hydroxyindol-1-yl)-2,2-dimethylpropan-1-one. 2003 Chem. Pharm. Bull. pmid:12520138
Hanson ML and Solomon KR New technique for estimating thresholds of toxicity in ecological risk assessment. 2002 Environ. Sci. Technol. pmid:12188350
Hanson ML et al. Evaluation of monochloroacetic acid (MCA) degradation and toxicity to Lemna gibba, Myriophyllum spicatum, and Myriophyllum sibiricum in aquatic microcosms. 2002 Aquat. Toxicol. pmid:12359395
Shimizu H et al. Therapeutic effects of glucose infusion on monochloroacetic acid exposure in rats. 2002 Toxicol Ind Health pmid:15119527
Olaniran AO et al. The aerobic dechlorination activities of two bacterial species isolated from a refuse dumpsite in Nigeria. 2002 Int. Microbiol. pmid:12102232
Mourad W et al. The value of CD34, myeloperoxidase and chloroacetate esterase (Leder) stain in the diagnosis of granulocytic sarcoma. 2001 Sep-Nov Ann Saudi Med pmid:17261930
Saghir SA et al. Kinetics of monochloroacetic acid in adult male rats after intravenous injection of a subtoxic and a toxic dose. 2001 J. Pharmacol. Exp. Ther. pmid:11160650
Lewandowicz A et al. Chlorine kinetic isotope effect on the fluoroacetate dehalogenase reaction. 2001 J. Am. Chem. Soc. pmid:11552840
Hage JC et al. Co-metabolic degradation of chlorinated hydrocarbons by Pseudomonas sp. strain DCA1. 2001 Appl. Microbiol. Biotechnol. pmid:11762603
Ellis DA et al. The fate and persistence of trifluoroacetic and chloroacetic acids in pond waters. 2001 Chemosphere pmid:11100931
Rozman KK and Doull J The role of time as a quantifiable variable of toxicity and the experimental conditions when Haber's c x t product can be observed: implications for therapeutics. 2001 J. Pharmacol. Exp. Ther. pmid:11181890
Huynh R et al. Anticoagulant properties of dextranmethylcarboxylate benzylamide sulfate (DMCBSu); a new generation of bioactive functionalized dextran. 2001 Carbohydr. Res. pmid:11403090
Dunphy CH et al. Acute promyelocytic leukemia, hypogranular variant, with uncharacteristic staining with chloroacetate esterase. 2001 Leuk. Lymphoma pmid:11699210
Porras SP et al. Resolution in capillary electrophoresis with nonaqueous methanol as solvent: theoretical prediction and experimental confirmation. 2001 Electrophoresis pmid:11699921
Dubourg L et al. Human kidney tubules detoxify chloroacetaldehyde, a presumed nephrotoxic metabolite of ifosfamide. 2001 J. Am. Soc. Nephrol. pmid:11461933
Spahr L et al. Rapid changes in alcoholic hepatitis histology under steroids: correlation with soluble intercellular adhesion molecule-1 in hepatic venous blood. 2001 J. Hepatol. pmid:11690703
Dartsch PC et al. Sodium monochloroacetate causes cytotoxic effects, an increased lactate and pyruvate level and induces ultra structural and cytoskeletal alterations in cultured kidney and liver epithelial cells. 2000 Hum Exp Toxicol pmid:10773845
Kim S and Picardal FW A novel bacterium that utilizes monochlorobiphenyls and 4-chlorobenzoate as growth substrates. 2000 FEMS Microbiol. Lett. pmid:10754252
Kuo CT and Chen HW Determination of 1,3-, 1,6-, 1,8-dinitropyrene and 1-nitropyrene in airborne particulate by column liquid chromatography with electrochemical detection. 2000 J Chromatogr A pmid:11128223
Sotlar K et al. Detection of c-kit mutation Asp 816 to Val in microdissected bone marrow infiltrates in a case of systemic mastocytosis associated with chronic myelomonocytic leukaemia. 2000 MP, Mol. Pathol. pmid:11040941
Sperr WR et al. Clinical and biologic diversity of leukemias occurring in patients with mastocytosis. 2000 Leuk. Lymphoma pmid:11042508
Fandy RF Synthesis of heterocyclic quinones containing bridgehead nitrogen atom from 2-aminonaphtho[2,3-d]thiazole-4,9-dione. 2000 Arch. Pharm. Res. pmid:11059820