2-chloro-acetic acid

2-chloro-acetic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 1900 references associated with 2-chloro-acetic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 2-chloro-acetic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-chloro-acetic acid

MeSH term MeSH ID Detail
Liver Diseases D008107 31 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Occupational Diseases D009784 42 associated lipids
Leukemia, Myeloid D007951 52 associated lipids
Reperfusion Injury D015427 65 associated lipids
Leukemia D007938 74 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Lung Neoplasms D008175 171 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 50 | Total 49

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 2-chloro-acetic acid

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Per page 10 20 50 100 | Total 727
Authors Title Published Journal PubMed Link
Senogles-Derham PJ et al. Toxicological aspects of treatment to remove cyanobacterial toxins from drinking water determined using the heterozygous P53 transgenic mouse model. 2003 Toxicon pmid:12875872
Bhat HK et al. Toxicokinetics of monochloroacetic acid: a whole-body autoradiography study. 1990 Toxicology pmid:2116687
Rozman KK The role of time in toxicology or Haber's c x t product. 2000 Toxicology pmid:10963859
Saghir SA et al. Validation of Haber's Rule (dose x time = constant) in rats and mice for monochloroacetic acid and 2,3,7,8-tetrachlorodibenzo-p-dioxin under conditions of kinetic steady state. 2005 Toxicology pmid:16076519
Chen CH et al. Chloroacetic acid induced neuronal cells death through oxidative stress-mediated p38-MAPK activation pathway regulated mitochondria-dependent apoptotic signals. 2013 Toxicology pmid:23103613
Daniel FB et al. Ninety-day toxicity study of sodium monochloroacetate in Sprague-Dawley rats. 1991 Toxicology pmid:2031251
Bryant BJ et al. Toxicity of monochloroacetic acid administered by gavage to F344 rats and B6C3F1 mice for up to 13 weeks. 1992 Toxicology pmid:1539174
Saghir SA and Rozman KK Kinetics of monochloroacetic acid at subtoxic and toxic doses in rats after single oral and dermal administrations. 2003 Toxicol. Sci. pmid:12915718
DeAngelo AB et al. Species and strain sensitivity to the induction of peroxisome proliferation by chloroacetic acids. 1989 Toxicol. Appl. Pharmacol. pmid:2815084
Green T and Prout MS Species differences in response to trichloroethylene. II. Biotransformation in rats and mice. 1985 Toxicol. Appl. Pharmacol. pmid:3929429
Speerschneider P and Dekant W Renal tumorigenicity of 1,1-dichloroethene in mice: the role of male-specific expression of cytochrome P450 2E1 in the renal bioactivation of 1,1-dichloroethene. 1995 Toxicol. Appl. Pharmacol. pmid:7839370
Masuda Y and Nakayama N Protective action of diethyldithiocarbamate and carbon disulfide against acute toxicities induced by 1,1-dichloroethylene in mice. 1983 Toxicol. Appl. Pharmacol. pmid:6314603
Hayes FD et al. Differential toxicity of monochloroacetate, monofluoroacetate and monoiodoacetate in rats. 1973 Toxicol. Appl. Pharmacol. pmid:4748142
Shimizu H et al. Therapeutic effects of glucose infusion on monochloroacetic acid exposure in rats. 2002 Toxicol Ind Health pmid:15119527
Dote T et al. Systemic effects and skin injury after experimental dermal exposure to monochloroacetic acid. 2003 Toxicol Ind Health pmid:15747777
Kato J et al. Lethal acute lung injury and hypoglycemia after subcutaneous administration of monochloroacetic acid. 2006 Toxicol Ind Health pmid:16898262
Kaphalia BS et al. Tissue distribution of monochloroacetic acid and its binding to albumin in rats. 1992 Jan-Apr Toxicol Ind Health pmid:1542885
Zurich MG et al. Evaluation of aggregating brain cell cultures for the detection of acute organ-specific toxicity. 2013 Toxicol In Vitro pmid:22954530
Roth RI et al. Stability of gels formed following coagulation of Limulus amebocyte lysate: lack of covalent crosslinking of coagulin. 1989 Thromb. Res. pmid:2781519
Reinhardt G Fibrin oligomers of high molecular weight soluble in MCA solutions: implications on the time course of fibrinI formation. 1980 Thromb. Res. pmid:7434320