2-chloro-acetic acid

2-chloro-acetic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 1900 references associated with 2-chloro-acetic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 2-chloro-acetic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-chloro-acetic acid

MeSH term MeSH ID Detail
Leukemia, Lymphoid D007945 18 associated lipids
Anemia D000740 21 associated lipids
Burns, Chemical D002057 3 associated lipids
Hypothermia D007035 19 associated lipids
Polycythemia D011086 4 associated lipids
Leukemia, Hairy Cell D007943 5 associated lipids
Trichinellosis D014235 9 associated lipids
Renal Insufficiency D051437 8 associated lipids
Bird Diseases D001715 4 associated lipids
Rhabdomyolysis D012206 9 associated lipids
Per page 10 20 50 | Total 49

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 2-chloro-acetic acid

Download all related citations
Per page 10 20 50 100 | Total 727
Authors Title Published Journal PubMed Link
Fowler JF et al. Allergy to cocamidopropyl betaine may be due to amidoamine: a patch test and product use test study. 1997 Contact Derm. pmid:9455630
DeAngelo AB et al. Failure of monochloroacetic acid and trichloroacetic acid administered in the drinking water to produce liver cancer in male F344/N rats. 1997 J Toxicol Environ Health pmid:9388534
McGrath JE and Harfoot CG Reductive dehalogenation of halocarboxylic acids by the phototrophic genera Rhodospirillum and Rhodopseudomonas. 1997 Appl. Environ. Microbiol. pmid:9251226
Loqueviel C et al. A 13C NMR study of 2-(13)C-chloroacetaldehyde, a metabolite of ifosfamide and cyclophosphamide, in the isolated perfused rabbit heart model. Initial observations on its cardiotoxicity and cardiac metabolism. 1997 Cell. Mol. Biol. (Noisy-le-grand) pmid:9298599
Giller S et al. Comparative genotoxicity of halogenated acetic acids found in drinking water. 1997 Mutagenesis pmid:9379909
Ong JK et al. Influence of hydroxypropyl beta-cyclodextrin on the stability of benzylpenicillin in chloroacetate buffer. 1997 J. Pharm. Pharmacol. pmid:9330202
Brashear WT et al. Electrospray analysis of biological samples for trace amounts of trichloroacetic acid, dichloroacetic acid, and monochloroacetic acid. 1997 J Anal Toxicol pmid:9288583
Kocabiyik S and Caba E Prevalence of monochloroacetate degrading genotypes among soil isolates of Pseudomonas sp. 1997-1998 Biodegradation pmid:15765582
Johnson PD et al. Cardiac teratogenicity of trichloroethylene metabolites. 1998 J. Am. Coll. Cardiol. pmid:9708489
Martínez D et al. Capillary zone electrophoresis with indirect UV detection of haloacetic acids in water. 1998 J Chromatogr A pmid:9652120
Elfarra AA et al. Species- and sex-related differences in metabolism of trichloroethylene to yield chloral and trichloroethanol in mouse, rat, and human liver microsomes. 1998 Drug Metab. Dispos. pmid:9698293
Wijeweera J et al. Interactive toxicity and stress protein expression by vinylidene chloride and monochloroacetate in precision-cut rat liver slices. 1998 Environ. Health Perspect. pmid:9860887
Liu JQ et al. Reaction mechanism of fluoroacetate dehalogenase from Moraxella sp. B. 1998 J. Biol. Chem. pmid:9812982
Sarzanini C et al. Preconcentration and separation of haloacetic acids by ion chromatography. 1999 J Chromatogr A pmid:10457481
Sarrión MN et al. Solid-phase microextraction coupled with gas chromatography-ion trap mass spectrometry for the analysis of haloacetic acids in water. 1999 J Chromatogr A pmid:10574209
Yan Z et al. Determination of chloral hydrate metabolites in human plasma by gas chromatography-mass spectrometry. 1999 J Pharm Biomed Anal pmid:10704096
Urbansky ET et al. Ascorbic acid reduction of residual active chlorine in potable water prior to halocarboxylate determination. 2000 J Environ Monit pmid:11256708
Klobusická M Reliability and limitations of cytochemistry in diagnosis of acute myeloid leukemia. Minireview. 2000 Neoplasma pmid:11263855
Donnelly PS et al. Carboxymethylation of cage amines: control of alkylation by metal ion coordination. 2000 Inorg Chem pmid:11151385
Dartsch PC et al. Sodium monochloroacetate causes cytotoxic effects, an increased lactate and pyruvate level and induces ultra structural and cytoskeletal alterations in cultured kidney and liver epithelial cells. 2000 Hum Exp Toxicol pmid:10773845
Kim S and Picardal FW A novel bacterium that utilizes monochlorobiphenyls and 4-chlorobenzoate as growth substrates. 2000 FEMS Microbiol. Lett. pmid:10754252
Kuo CT and Chen HW Determination of 1,3-, 1,6-, 1,8-dinitropyrene and 1-nitropyrene in airborne particulate by column liquid chromatography with electrochemical detection. 2000 J Chromatogr A pmid:11128223
Sotlar K et al. Detection of c-kit mutation Asp 816 to Val in microdissected bone marrow infiltrates in a case of systemic mastocytosis associated with chronic myelomonocytic leukaemia. 2000 MP, Mol. Pathol. pmid:11040941
Sperr WR et al. Clinical and biologic diversity of leukemias occurring in patients with mastocytosis. 2000 Leuk. Lymphoma pmid:11042508
Fandy RF Synthesis of heterocyclic quinones containing bridgehead nitrogen atom from 2-aminonaphtho[2,3-d]thiazole-4,9-dione. 2000 Arch. Pharm. Res. pmid:11059820
Rozman KK The role of time in toxicology or Haber's c x t product. 2000 Toxicology pmid:10963859
Abdel-Gawad SM et al. Synthesis and antifungal activity of novel pyrano[2',3':4,5]thiazolo[2,3-b]quinazolines, pyrido[2',3':4,5]thiazolo[2,3-b]quinazolines and pyrazolo[2',3':4,5]thiazolo[2,3-b]quinazolines. 2000 Farmaco pmid:10966160
Ysebaert DK et al. Identification and kinetics of leukocytes after severe ischaemia/reperfusion renal injury. 2000 Nephrol. Dial. Transplant. pmid:11007823
Durán Merás I et al. Complexation of antibacterial quinolonic acid and cinolonic derivatives with Zn(II) and Al(III): application to their determination in human urine. 2000 Analyst pmid:11002930
Friend DS et al. Senescent jejunal mast cells and eosinophils in the mouse preferentially translocate to the spleen and draining lymph node, respectively, during the recovery phase of helminth infection. 2000 J. Immunol. pmid:10861071
Bennett JM et al. Hypergranular promyelocytic leukemia: correlation between morphology and chromosomal translocations including t(15;17) and t(11;17). 2000 Leukemia pmid:10914542
de Nooy AE et al. Synthesis and preliminary characterisation of charged derivatives and hydrogels from scleroglucan. 2000 Carbohydr. Res. pmid:10702878
Wilson RI and Mabury SA Photodegradation of metolachlor: isolation, identification, and quantification of monochloroacetic acid. 2000 J. Agric. Food Chem. pmid:10725179
Saghir SA et al. Kinetics of monochloroacetic acid in adult male rats after intravenous injection of a subtoxic and a toxic dose. 2001 J. Pharmacol. Exp. Ther. pmid:11160650
Lewandowicz A et al. Chlorine kinetic isotope effect on the fluoroacetate dehalogenase reaction. 2001 J. Am. Chem. Soc. pmid:11552840
Hage JC et al. Co-metabolic degradation of chlorinated hydrocarbons by Pseudomonas sp. strain DCA1. 2001 Appl. Microbiol. Biotechnol. pmid:11762603
Ellis DA et al. The fate and persistence of trifluoroacetic and chloroacetic acids in pond waters. 2001 Chemosphere pmid:11100931
Rozman KK and Doull J The role of time as a quantifiable variable of toxicity and the experimental conditions when Haber's c x t product can be observed: implications for therapeutics. 2001 J. Pharmacol. Exp. Ther. pmid:11181890
Huynh R et al. Anticoagulant properties of dextranmethylcarboxylate benzylamide sulfate (DMCBSu); a new generation of bioactive functionalized dextran. 2001 Carbohydr. Res. pmid:11403090
Dunphy CH et al. Acute promyelocytic leukemia, hypogranular variant, with uncharacteristic staining with chloroacetate esterase. 2001 Leuk. Lymphoma pmid:11699210
Porras SP et al. Resolution in capillary electrophoresis with nonaqueous methanol as solvent: theoretical prediction and experimental confirmation. 2001 Electrophoresis pmid:11699921
Dubourg L et al. Human kidney tubules detoxify chloroacetaldehyde, a presumed nephrotoxic metabolite of ifosfamide. 2001 J. Am. Soc. Nephrol. pmid:11461933
Spahr L et al. Rapid changes in alcoholic hepatitis histology under steroids: correlation with soluble intercellular adhesion molecule-1 in hepatic venous blood. 2001 J. Hepatol. pmid:11690703
Mourad W et al. The value of CD34, myeloperoxidase and chloroacetate esterase (Leder) stain in the diagnosis of granulocytic sarcoma. 2001 Sep-Nov Ann Saudi Med pmid:17261930
Hanson ML and Solomon KR New technique for estimating thresholds of toxicity in ecological risk assessment. 2002 Environ. Sci. Technol. pmid:12188350
Hanson ML et al. Evaluation of monochloroacetic acid (MCA) degradation and toxicity to Lemna gibba, Myriophyllum spicatum, and Myriophyllum sibiricum in aquatic microcosms. 2002 Aquat. Toxicol. pmid:12359395
Shimizu H et al. Therapeutic effects of glucose infusion on monochloroacetic acid exposure in rats. 2002 Toxicol Ind Health pmid:15119527
Olaniran AO et al. The aerobic dechlorination activities of two bacterial species isolated from a refuse dumpsite in Nigeria. 2002 Int. Microbiol. pmid:12102232
Nasr MN and Said SA Novel 3,3a,4,5,6,7-hexahydroindazole and arylthiazolylpyrazoline derivatives as anti-inflammatory agents. 2003 Arch. Pharm. (Weinheim) pmid:14677148
Helaleh MI et al. Vacancy ion-exclusion chromatography of haloacetic acids on a weakly acidic cation-exchange resin. 2003 J Chromatogr A pmid:12830885
Bakeas EB et al. Determination of chloroacetates in atmospheric particulate matter. 2003 Environ. Sci. Technol. pmid:12831014
Peters RJ Chloroacetic acids in European soils and vegetation. 2003 J Environ Monit pmid:12729268
Fahimi IJ et al. Formation of chloroacetic acids from soil, humic acid and phenolic moieties. 2003 Chemosphere pmid:12738276
Wong CS et al. Measurement of 13C/12C of chloroacetic acids by gas chromatography/combustion/isotope ratio mass spectrometry. 2003 Chemosphere pmid:12504128
Senogles-Derham PJ et al. Toxicological aspects of treatment to remove cyanobacterial toxins from drinking water determined using the heterozygous P53 transgenic mouse model. 2003 Toxicon pmid:12875872
Saghir SA and Rozman KK Kinetics of monochloroacetic acid at subtoxic and toxic doses in rats after single oral and dermal administrations. 2003 Toxicol. Sci. pmid:12915718
St-Pierre A et al. Evaluation of the influence of chloroacetic acids on the pharmacokinetics of trihalomethanes in the rat. 2003 J. Toxicol. Environ. Health Part A pmid:14612337
Basharova GR et al. [Occupational risk and evaluation of health damage in workers engaged in organochlorine compound production]. 2003 Med Tr Prom Ekol pmid:14593650
Dote T et al. Systemic effects and skin injury after experimental dermal exposure to monochloroacetic acid. 2003 Toxicol Ind Health pmid:15747777
Ammini CV et al. Pharmacologic or genetic ablation of maleylacetoacetate isomerase increases levels of toxic tyrosine catabolites in rodents. 2003 Biochem. Pharmacol. pmid:14599561
Glossmann JP et al. Extramedullary acute myeloid leukemia (granulocytic sarcoma) with arm paresis, maculopapular exanthema and organ involvement. 2003 Leuk. Lymphoma pmid:14565668
Repp R et al. Phase I clinical trial of the bispecific antibody MDX-H210 (anti-FcgammaRI x anti-HER-2/neu) in combination with Filgrastim (G-CSF) for treatment of advanced breast cancer. 2003 Br. J. Cancer pmid:14676800
Hill KE and Weightman AJ Horizontal transfer of dehalogenase genes on IncP1beta plasmids during bacterial adaptation to degrade alpha-halocarboxylic acids. 2003 FEMS Microbiol. Ecol. pmid:19719596
Jo SK et al. Detection of inflammation following renal ischemia by magnetic resonance imaging. 2003 Kidney Int. pmid:12787394
Demopoulos VJ et al. A facile preparation of 1-(6-hydroxyindol-1-yl)-2,2-dimethylpropan-1-one. 2003 Chem. Pharm. Bull. pmid:12520138
Pirson J et al. An unusual cause of burn injury: skin exposure to monochloroacetic acid. 2003 Nov-Dec J Burn Care Rehabil pmid:14610430
Kawase T and Oguro A Granulocyte colony-stimulating factor synergistically augments 1,25-dihydroxyvitamin D3-induced monocytic differentiation in murine bone marrow cell cultures. 2004 Horm. Metab. Res. pmid:15305226
Hanson ML and Solomon KR Haloacetic acids in the aquatic environment. Part I: macrophyte toxicity. 2004 Environ. Pollut. pmid:15182970
Hanson ML and Solomon KR Haloacetic acids in the aquatic environment. Part II: ecological risk assessment. 2004 Environ. Pollut. pmid:15182971
Lookman R et al. Batch-test study on the dechlorination of 1,1,1-trichloroethane in contaminated aquifer material by zero-valent iron. 2004 J. Contam. Hydrol. pmid:15358490
Ghosh AK and Kim JH Stereoselective chloroacetate aldol reactions: syntheses of acetate aldol equivalents and darzens glycidic esters. 2004 Org. Lett. pmid:15281754
Kim K et al. Change of monochloroacetic acid to biodegradable organic acids by hydrothermal reaction. 2004 J. Hazard. Mater. pmid:15081173
Rodrigues JA et al. Diastereoselective synthesis of cularine alkaloids via enium ions and an easy entry to isoquinolines by aza-Wittig electrocyclic ring closure. 2004 J. Org. Chem. pmid:15104427
Hassoun EA and Kini V Effects of superoxide dismutase and polyclonal tumor necrosis factor-alpha antibodies on chloroacetate-induced cellular death and superoxide anion production by J774.A1 macrophages. 2004 Comp. Biochem. Physiol. C Toxicol. Pharmacol. pmid:15450858
Mezö G et al. Synthesis and structural characterization of bioactive peptide conjugates using thioether linkage approaches. 2004 J. Pept. Sci. pmid:15635622
Plewa MJ et al. Chemical and biological characterization of newly discovered iodoacid drinking water disinfection byproducts. 2004 Environ. Sci. Technol. pmid:15487777
Song JS et al. Genetic organization of the dhlA gene encoding 1,2-dichloroethane dechlorinase from Xanthobacter flavus UE15. 2004 J. Microbiol. pmid:15459646
Toshina Y et al. Hepatic injury and gluconeogenesis after subcutaneous injection of monochloroacetic acid in rats. 2004 Environ Health Prev Med pmid:21432300
Foks H et al. Synthesis and tuberculostatic activity of some (4-phenylpiperazin-1-ylmethyl)-1,3,4-oxadiazole and (4-phenylpiperazin-1-ylmethyl)-1,2,4-triazole derivatives. 2004 Nov-Dec Acta Pol Pharm pmid:15794341
Schlund S et al. Geometry and cooperativity effects in adenosine-carboxylic acid complexes. 2005 J. Am. Chem. Soc. pmid:16287303
Calinescu C et al. Carboxymethyl high amylose starch (CM-HAS) as excipient for Escherichia coli oral formulations. 2005 Eur J Pharm Biopharm pmid:15848056
St-Pierre A et al. Characterization of the metabolic interaction between trihalomethanes and chloroacetic acids using rat liver microsomes. 2005 J. Toxicol. Environ. Health Part A pmid:15799452
Saghir SA et al. Validation of Haber's Rule (dose x time = constant) in rats and mice for monochloroacetic acid and 2,3,7,8-tetrachlorodibenzo-p-dioxin under conditions of kinetic steady state. 2005 Toxicology pmid:16076519
Jokinen MP et al. Characterization of spontaneous and chemically induced cardiac lesions in rodent model systems: the national toxicology program experience. 2005 Cardiovasc. Toxicol. pmid:16046796
Sakai A et al. Monochloroacetic acid inhibits liver gluconeogenesis by inactivating glyceraldehyde-3-phosphate dehydrogenase. 2005 Chem. Res. Toxicol. pmid:15720133
Torz M and Beschkov V Biodegradation of monochloroacetic acid used as a sole carbon and energy source by Xanthobacter autotrophicus GJ10 strain in batch and continuous culture. 2005 Biodegradation pmid:15865156
Ge HC and Luo DK Preparation of carboxymethyl chitosan in aqueous solution under microwave irradiation. 2005 Carbohydr. Res. pmid:15854605
Jackson WA et al. Application of a dialysis sampler to monitor phytoremediation processes. 2005 Environ Monit Assess pmid:16418910
Laturnus F et al. Natural formation and degradation of chloroacetic acids and volatile organochlorines in forest soil--challenges to understanding. 2005 Environ Sci Pollut Res Int pmid:16137159
Hinckley AF et al. Late pregnancy exposures to disinfection by-products and growth-related birth outcomes. 2005 Environ. Health Perspect. pmid:16330369
Mason LJ et al. Stable expression of a recombinant human antinucleosome antibody to investigate relationships between antibody sequence, binding properties, and pathogenicity. 2005 Arthritis Res. Ther. pmid:16207338
Glawe C et al. In vivo characterization of developing chronic pancreatitis in rats. 2005 Lab. Invest. pmid:15543202
Amr Ael-G et al. Synthesis and reactions of some new substituted pyridine and pyrimidine derivatives as analgesic, anticonvulsant and antiparkinsonian agents. 2005 Arch. Pharm. (Weinheim) pmid:16134091
Yang G et al. On-line simultaneous removal of human serum albumin and enrichment of doxazosin using a weak cation-exchange monolithic column. 2006 J Chromatogr A pmid:16879834
Sun S and Wang A Adsorption kinetics of Cu(II) ions using N,O-carboxymethyl-chitosan. 2006 J. Hazard. Mater. pmid:16337742
Wander MC et al. The role of structured water in the calibration and interpretation of theoretical IR spectra. 2006 Spectrochim Acta A Mol Biomol Spectrosc pmid:16490385
Ye BX et al. [Study advance on haloacetic acids in drinking water]. 2006 Wei Sheng Yan Jiu pmid:16921773
Kato J et al. Lethal acute lung injury and hypoglycemia after subcutaneous administration of monochloroacetic acid. 2006 Toxicol Ind Health pmid:16898262
Faisal Siddiqui M et al. Micronuclei induction and chromosomal aberrations in Rattus norvegicus by chloroacetic acid and chlorobenzene. 2006 Ecotoxicol. Environ. Saf. pmid:16647117
Kono K [Chemical burn]. 2006 Chudoku Kenkyu pmid:16715898