2-chloro-acetic acid

2-chloro-acetic acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 1900 references associated with 2-chloro-acetic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 2-chloro-acetic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-chloro-acetic acid

MeSH term MeSH ID Detail
Neurotoxicity Syndromes D020258 34 associated lipids
Leukemia, Myelomonocytic, Acute D015479 6 associated lipids
Leukemia, Myelomonocytic, Chronic D015477 1 associated lipids
Oropharyngeal Neoplasms D009959 2 associated lipids
Pharyngeal Neoplasms D010610 4 associated lipids
Solitary Pulmonary Nodule D003074 1 associated lipids
Leukemia, Mast-Cell D007946 1 associated lipids
Hemangioendothelioma D006390 1 associated lipids
Mastocytosis D008415 5 associated lipids
Factor XIII Deficiency D005177 1 associated lipids
Per page 10 20 50 | Total 49

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 2-chloro-acetic acid

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Per page 10 20 50 100 | Total 727
Authors Title Published Journal PubMed Link
Chen YS and Lu DW [The diagnostic value of chloroacetate esterase stain in acute leukemias--observation of 70 cases]. 1983 Zhonghua Nei Ke Za Zhi pmid:6191929
Bai Y et al. [Investigation on coal work's production use of chloroacetic acid in one province]. 2010 Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi pmid:21126433
Chen LM et al. [Gas chromatography for determination of sodium monochloroacetate in biological samples]. 2006 Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi pmid:16737600
Ye BX et al. [Study advance on haloacetic acids in drinking water]. 2006 Wei Sheng Yan Jiu pmid:16921773
Xiang H and Lu X [Study advance on reproductive and developmental toxicity of haloacetic acids in drinking water]. 2008 Wei Sheng Yan Jiu pmid:18589619
Escobar-Hoyos LF et al. Genotoxic and clastogenic effects of monohaloacetic acid drinking water disinfection by-products in primary human lymphocytes. 2013 Water Res. pmid:23602619
Milićević NM and Milićević Z Naphthol AS D chloroacetate esterase-positive macrophages in the cortico-medullary zone of the normal rat thymus. 1985 Virchows Arch., B, Cell Pathol. pmid:2868565
Milićević NM et al. Macrophages of the rat thymus after cyclosporin treatment. Histochemical, enzymehistochemical and immunohistochemical study. 1989 Virchows Arch., B, Cell Pathol. pmid:2569784
Schlayer HJ et al. Beta-glucuronidase and chloroacetate-esterase staining discriminates rat liver sinusoidal endothelial cells from Kupffer cells in primary culture. 1988 Virchows Arch., B, Cell Pathol. pmid:2457275
Kikuchi M et al. Immunohistological study of histiocytic necrotizing lymphadenitis. 1986 Virchows Arch A Pathol Anat Histopathol pmid:2941916
Laeng RH et al. Heterogeneous malignant non Hodgkin's lymphomas as a causative disorder in lethal midline granuloma. 1989 Virchows Arch A Pathol Anat Histopathol pmid:2527438
Bourgeois N et al. The thymus as haematopoietic tissue of non-lymphoid cells. 1981 Virchows Arch A Pathol Anat Histol pmid:7281489
Huson LE et al. Modulation of the immunogenicity of the Trypanosoma congolense cysteine protease, congopain, through complexation with alpha(2)-macroglobulin. 2009 Nov-Dec Vet. Res. pmid:19549486
Quick MP et al. Sodium monochloroacetate poisoning of cattle and sheep. 1983 Vet. Rec. pmid:6623874
Facklam NR and Kociba GJ Cytochemical characterization of feline leukemic cells. 1986 Vet. Pathol. pmid:2421477
Facklam NR and Kociba GJ Cytochemical characterization of leukemic cells from 20 dogs. 1985 Vet. Pathol. pmid:2412332
Baker PE and Knoblock KF Bovine costimulator. II. Generation and maintenance of a bovine costimulator-dependent bovine lymphoblastoid cell line. 1982 Vet. Immunol. Immunopathol. pmid:6181609
Raskin W and Canada A Acute topical exposure to a mixture of benzene, chloracetyl chloride and xylidine. 1981 Vet Hum Toxicol pmid:7303472
Gelain ME et al. Chronic eosinophilic leukemia in a cat: cytochemical and immunophenotypical features. 2006 Vet Clin Pathol pmid:17123254
Nikol'skiÄ­ IS et al. [Cytochemical characteristics of cells forming mast cell-lymphocyte rosettes]. 1985 Tsitologiia pmid:3879025
Senogles-Derham PJ et al. Toxicological aspects of treatment to remove cyanobacterial toxins from drinking water determined using the heterozygous P53 transgenic mouse model. 2003 Toxicon pmid:12875872
Bhat HK et al. Toxicokinetics of monochloroacetic acid: a whole-body autoradiography study. 1990 Toxicology pmid:2116687
Rozman KK The role of time in toxicology or Haber's c x t product. 2000 Toxicology pmid:10963859
Saghir SA et al. Validation of Haber's Rule (dose x time = constant) in rats and mice for monochloroacetic acid and 2,3,7,8-tetrachlorodibenzo-p-dioxin under conditions of kinetic steady state. 2005 Toxicology pmid:16076519
Chen CH et al. Chloroacetic acid induced neuronal cells death through oxidative stress-mediated p38-MAPK activation pathway regulated mitochondria-dependent apoptotic signals. 2013 Toxicology pmid:23103613
Daniel FB et al. Ninety-day toxicity study of sodium monochloroacetate in Sprague-Dawley rats. 1991 Toxicology pmid:2031251
Bryant BJ et al. Toxicity of monochloroacetic acid administered by gavage to F344 rats and B6C3F1 mice for up to 13 weeks. 1992 Toxicology pmid:1539174
Saghir SA and Rozman KK Kinetics of monochloroacetic acid at subtoxic and toxic doses in rats after single oral and dermal administrations. 2003 Toxicol. Sci. pmid:12915718
DeAngelo AB et al. Species and strain sensitivity to the induction of peroxisome proliferation by chloroacetic acids. 1989 Toxicol. Appl. Pharmacol. pmid:2815084
Green T and Prout MS Species differences in response to trichloroethylene. II. Biotransformation in rats and mice. 1985 Toxicol. Appl. Pharmacol. pmid:3929429
Speerschneider P and Dekant W Renal tumorigenicity of 1,1-dichloroethene in mice: the role of male-specific expression of cytochrome P450 2E1 in the renal bioactivation of 1,1-dichloroethene. 1995 Toxicol. Appl. Pharmacol. pmid:7839370
Masuda Y and Nakayama N Protective action of diethyldithiocarbamate and carbon disulfide against acute toxicities induced by 1,1-dichloroethylene in mice. 1983 Toxicol. Appl. Pharmacol. pmid:6314603
Hayes FD et al. Differential toxicity of monochloroacetate, monofluoroacetate and monoiodoacetate in rats. 1973 Toxicol. Appl. Pharmacol. pmid:4748142
Shimizu H et al. Therapeutic effects of glucose infusion on monochloroacetic acid exposure in rats. 2002 Toxicol Ind Health pmid:15119527
Dote T et al. Systemic effects and skin injury after experimental dermal exposure to monochloroacetic acid. 2003 Toxicol Ind Health pmid:15747777
Kato J et al. Lethal acute lung injury and hypoglycemia after subcutaneous administration of monochloroacetic acid. 2006 Toxicol Ind Health pmid:16898262
Kaphalia BS et al. Tissue distribution of monochloroacetic acid and its binding to albumin in rats. 1992 Jan-Apr Toxicol Ind Health pmid:1542885
Zurich MG et al. Evaluation of aggregating brain cell cultures for the detection of acute organ-specific toxicity. 2013 Toxicol In Vitro pmid:22954530
Roth RI et al. Stability of gels formed following coagulation of Limulus amebocyte lysate: lack of covalent crosslinking of coagulin. 1989 Thromb. Res. pmid:2781519
Reinhardt G Fibrin oligomers of high molecular weight soluble in MCA solutions: implications on the time course of fibrinI formation. 1980 Thromb. Res. pmid:7434320
Ragaz S et al. Bleeding disorder with abnormal wound healing, acid-soluble clots and normal factor XIII. 1976 Thromb. Haemost. pmid:1037151
Taubenfeld SM et al. A monoclonal antibody against a peptide sequence of fibrinogen gamma chain acts as an inhibitor of factor XIII-mediated crosslinking of human fibrin. 1995 Thromb. Haemost. pmid:8571322
Yang MH et al. Determination of small amounts of boron by radiation decomposition of chloroacetic acid solution. 1979 Talanta pmid:18962508
Java S et al. Simultaneous determination of lead and thallium by potentiometric stripping. 1985 Talanta pmid:18963949
Nan Z et al. Chelatometric titration of tin in non-ferrous alloys with hedta. 1985 Talanta pmid:18963967
Alhooshani K et al. Electromembrane extraction and HPLC analysis of haloacetic acids and aromatic acetic acids in wastewater. 2011 Talanta pmid:22063518
Luzhnikov EA et al. [Metabolism of 1,2-dichloroethane in the human body in acute poisonings]. 1985 Apr-Jun Sud. Med. Ekspert. pmid:4024199
Abdelhalim MM et al. Synthesis and biological evaluation of some nitrogen containing steroidal heterocycles. 2011 Steroids pmid:20849869
Longo UG et al. Scaffolds in tendon tissue engineering. 2012 Stem Cells Int pmid:22190961
Katayama T et al. Characteristics of granulocyte-macrophage colony formation in patients with chronic myelomonocytic leukemia. 1982 Stem Cells pmid:6183760