2-bromoacetic acid

2-bromoacetic acid is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 872 references associated with 2-bromoacetic acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for 2-bromoacetic acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-bromoacetic acid

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Neuroblastoma D009447 66 associated lipids
Total 3

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 2-bromoacetic acid

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Authors Title Published Journal PubMed Link
Warren JC et al. Structure of the steroid-binding site of human placental estradiol-17beta-dehydrogenase. 1977 Am. J. Obstet. Gynecol. pmid:607808
Bellmann B and Witzel H [Steric requirements for the carboxymethylation of His 12 in ribonuclease A studied by 2'- and 3'-bromoacetylesters of modified nucleosides (author's transl)]. 1981 Hoppe-Seyler's Z. Physiol. Chem. pmid:6273287
Postnikova GB et al. [Electron transfer in hemoproteins. VIII. Influence of ionic strength on the rate of reduction of ferricytochrome c by oxymyoglobin derivatives, chemically modified at histidine residues]. 1982 Jan-Feb Mol. Biol. (Mosk.) pmid:6280031
Postnikova GB et al. [Electron transport in hemoproteins. VIII. The effect of chemical modification of ferricytochrome C on the rate of its reduction by oxymyoglobin]. 1984 Jan-Feb Mol. Biol. (Mosk.) pmid:6323975
Chiou CY Treatment of neuroblastoma in mice with bromoacetylcholine and bromoacetate. 1978 J Pharm Sci pmid:641717
Khalifah RG et al. Molecular basis for catalytic activity changes in active-site-modified carbonic anhydrases: a13C magnetic resonance view. 1984 Ann. N. Y. Acad. Sci. pmid:6430147
Khalifah RG et al. Paramagnetic 1H and 13C NMR studies on cobalt-substituted human carbonic anhydrase I carboxymethylated at active site histidine-200: molecular basis for the changes in catalytic properties induced by the modification. 1984 Biochemistry pmid:6432037
Hummel CF et al. Chemical modification of ribonuclease A with 4-arsono-2-nitrofluorobenzene. 1984 Int. J. Pept. Protein Res. pmid:6434458
Chapman SK et al. Ornithine decarboxylase activity and the growth of neuroblastoma cells. The effects of bromoacetylcholine, bromoacetate and 1,3-diaminopropane. 1978 Biochem. Pharmacol. pmid:656110
Brandsnes O et al. A transition-state analysis of the enzyme catalysis in the affinity labelling of horse-liver alcohol dehydrogenase by bromoacids. 1982 Eur. J. Biochem. pmid:6751820
Stelma GN and Bergdoll MS Inactivation of staphylococcal enterotoxin A by chemical modification. 1982 Biochem. Biophys. Res. Commun. pmid:6807298
Chin CC et al. Synthesis of 2-bromoacetamidoestrone methyl ether and study of the steroid-binding site of human placental estradiol 17 beta-dehydrogenase. 1980 J. Biol. Chem. pmid:6928850
Chen WS et al. Inactivation of liver alcohol dehydrogenases and inhibition of ethanol metabolism by ambivalent active-site-directed reagents. 1981 J. Med. Chem. pmid:7009869
Dahl KH and McKinley-Mckee JS Enzymatic catalysis in the affinity labelling of liver alcohol dehydrogenase with haloacids. 1981 Eur. J. Biochem. pmid:7028481
Wu GP et al. [Studies on the quantitative structure-activity relationship of the schistosomicidal substances--bromoacetic esters]. 1982 Yao Xue Xue Bao pmid:7168332
Plevinskis VP [Effect of high-frequency ultrasound on metabolic resistance of the retina and optic nerve to toxic lesions]. 1981 Oftalmol Zh pmid:7243169
Holmes SD et al. Affinity labelling of the human uterine progesterone receptor with 21-, 16 alpha- and 11 alpha-bromoacetoxyprogesterones. 1981 Endocrinology pmid:7250064
Stratton CE et al. Cytotoxicity and deoxyribonucleic acid damage associated with bromoacetate. 1981 Biochem. Pharmacol. pmid:7271843
Numazawa M and Osawa Y Synthesis of 16 alpha-bromoacetoxy androgens and 17 beta-bromoacetylamino-4-androsten-3-one: potential affinity labels of human placental aromatase. 1981 Steroids pmid:7303027
Kihira K et al. Synthesis of (22R and 22S)-3 alpha, 7 alpha, 22-trihydroxy-5 beta-cholan-24-oic acids and structure of haemulcholic acid, a unique bile acid isolated from fish bile. 1981 J. Lipid Res. pmid:7320628
Bai FX et al. [Studies on chemotherapeutic agents against Schistosomiasis japonica. I. Synthesis of alcoholic and phenolic esters of monobromoacetic acid]. 1981 Yao Xue Xue Bao pmid:7324962
Jones AR and Wells G The comparative metabolism of 2-bromoethanol and ethylene oxide in the rat. 1981 Xenobiotica pmid:7336757
Chiou GC and Martin MK Chemotherapy of neuroblastoma in mice with anticancer agents. 1980 J Pharm Sci pmid:7381752
Kang SH et al. A new affinity purification procedure for DNA-binding proteins using bromoacetyl agarose. 1995 Nucleic Acids Res. pmid:7610067
Fahy E et al. Design and synthesis of polyacrylamide-based oligonucleotide supports for use in nucleic acid diagnostics. 1993 Nucleic Acids Res. pmid:7684127
Sternbach H et al. Affinity labelling of tRNA nucleotidyltransferase from baker's yeast with tRNAPhe modified on the 3'-terminus. 1976 Eur. J. Biochem. pmid:786619
van der Ploeg J et al. Adaptation of Xanthobacter autotrophicus GJ10 to bromoacetate due to activation and mobilization of the haloacetate dehalogenase gene by insertion element IS1247. 1995 J. Bacteriol. pmid:7868610
Englebretsen DR and Harding DR High yield, directed immobilization of a peptide-ligand onto a beaded cellulose support. 1994 Nov-Dec Pept. Res. pmid:7888714
Robey FA Bromoacetylated synthetic peptides. Starting materials for cyclic peptides, peptomers, and peptide conjugates. 1994 Methods Mol. Biol. pmid:7894610
Linder RE et al. Acute spermatogenic effects of bromoacetic acids. 1994 Fundam Appl Toxicol pmid:8050637
Ito K et al. Evidence for an essential histidine residue on active site of human urinary DNase I: carboxymethylation and carbethoxylation. 1994 Arch. Biochem. Biophys. pmid:8053672
Ishimori Y and Rokugawa K Stable liposomes for assays of human sera. 1993 Clin. Chem. pmid:8330404
el Garrouj D et al. Steroidal affinity labels of the estrogen receptor. 1. 17 alpha-(Bromoacetoxy)alkyl/alkynylestradiols. 1993 J. Med. Chem. pmid:8411015
Parrish JM et al. Haloacetate-induced oxidative damage to DNA in the liver of male B6C3F1 mice. 1996 Toxicology pmid:8658551
Grant KB and Dervan PB Sequence-specific alkylation and cleavage of DNA mediated by purine motif triple helix formation. 1996 Biochemistry pmid:8823165
Swamy N et al. Roles of the structure and orientation of ligands and ligand mimics inside the ligand-binding pocket of the vitamin D-binding protein. 1997 Biochemistry pmid:9200691
McGrath JE and Harfoot CG Reductive dehalogenation of halocarboxylic acids by the phototrophic genera Rhodospirillum and Rhodopseudomonas. 1997 Appl. Environ. Microbiol. pmid:9251226
Martínez D et al. Capillary zone electrophoresis with indirect UV detection of haloacetic acids in water. 1998 J Chromatogr A pmid:9652120
Chen QX et al. Kinetics of inhibition of Penaeus penicillatus acid phosphatase by bromoacetic acid. 1998 Biochem. Mol. Biol. Int. pmid:9801789
Novak MJ New minimal substrate structural requirements in the enzymatic peroxidation of alkenes with soybean lipoxygenase. 1999 Bioorg. Med. Chem. Lett. pmid:9990451