Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Osteoarthritis, Spine D055013 2 associated lipids
Osteophyte D054850 2 associated lipids
Monckeberg Medial Calcific Sclerosis D050380 1 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Stroke D020521 32 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Thrombophilia D019851 6 associated lipids
Arthralgia D018771 8 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Reperfusion Injury D015427 65 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Basselin-Eiweida M and Kaneshiro ES Detection of two distinct transporter systems for 2-deoxyglucose uptake by the opportunistic pathogen Pneumocystis carinii. 2001 Biochim. Biophys. Acta pmid:11718673
Kohlstock UM et al. Cys359 of GrdD is the active-site thiol that catalyses the final step of acetyl phosphate formation by glycine reductase from Eubacterium acidaminophilum. 2001 Eur. J. Biochem. pmid:11737196
Massaro D In vivo protein secretion by lung. Evidence for active secretion and interspecies differences. 1975 J. Clin. Invest. pmid:1173812
Merker MP et al. Intracellular redox status affects transplasma membrane electron transport in pulmonary arterial endothelial cells. 2002 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:11741813
Rudnick G and Abeles RH Reaction mechanism and structure of the active site of proline racemase. 1975 Biochemistry pmid:1174513
Bogliolo M et al. Alternative metabolic pathways for energy supply and resistance to apoptosis in Fanconi anaemia. 2002 Mutagenesis pmid:11752230
Petitpierre-Gabathuler MP and Ryser HJ Cellular uptake of soluble and aggregated ferritin: distinction between pinocytosis and phagocytosis. 1975 J. Cell. Sci. pmid:1176545
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Janusz MJ et al. Moderation of iodoacetate-induced experimental osteoarthritis in rats by matrix metalloproteinase inhibitors. 2001 Osteoarthr. Cartil. pmid:11795995
Takahashi S et al. Substrate-dependence of reduction of MTT: a tetrazolium dye differs in cultured astroglia and neurons. 2002 Neurochem. Int. pmid:11821152
Jaspers HT and van Steveninck J Transport-associated phosphorylation of 2-deoxy-D-glucose in Saccharomyces fragilis. 1975 Biochim. Biophys. Acta pmid:1182170
Siflinger A et al. Uptake of 125I albumin by the endothelial surface of the isolated dog common carotid artery: effect of certain physical factors and metabolic inhibitors. 1975 Cardiovasc. Res. pmid:1182724
Marbach EP et al. Sodium iodoacetate as an antiglycolytic agent in blood samples. 1975 Clin. Chem. pmid:1183004
Zółtowska K Purification and characterization of alpha-amylases from the intestine and muscle of ascaris suum (Nematoda). 2001 Acta Biochim. Pol. pmid:11833785
Abdo MA et al. Inhibitors of caspase homologues suppress an apoptotic phenotype in cultured rabbit corpora lutea. 2001 Reprod. Fertil. Dev. pmid:11833936
Edwards RH et al. Metabolic changes associated with the slowing of relaxation in fatigued mouse muscle. 1975 J. Physiol. (Lond.) pmid:1185665
Sugisawa T and Hoshino T Purification and properties of membrane-bound D-sorbitol dehydrogenase from Gluconobacter suboxydans IFO 3255. 2002 Biosci. Biotechnol. Biochem. pmid:11866120
pmid:11889583
pmid:11893026
Lasch J Fluorescence and chemical reactivity as empirical indices of matrix-induced alterations in immobilized enzymes. 1975 Acta Biol. Med. Ger. pmid:1189829