| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Wounds and Injuries | D014947 | 20 associated lipids |
| Burns | D002056 | 34 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Sarcoma 180 | D012510 | 21 associated lipids |
Iodoacetic acid
Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
Cross Reference
Introduction
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Iodoacetic acid?
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
PubChem Associated disorders and diseases
What pathways are associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Iodoacetic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Iodoacetic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Iodoacetic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Iodoacetic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Orita S et al. | Pain-related sensory innervation in monoiodoacetate-induced osteoarthritis in rat knees that gradually develops neuronal injury in addition to inflammatory pain. | 2011 | BMC Musculoskelet Disord | pmid:21679434 |
| Ulanovskaya OA et al. | A pairwise chemical genetic screen identifies new inhibitors of glucose transport. | 2011 | Chem. Biol. | pmid:21338919 |
| Plewa MJ et al. | Mammalian cell cytotoxicity and genotoxicity of the haloacetic acids, a major class of drinking water disinfection by-products. | 2010 Oct-Dec | Environ. Mol. Mutagen. | pmid:20839218 |
| Swearingen CA et al. | A short-term pharmacodynamic model for monitoring aggrecanase activity: injection of monosodium iodoacetate (MIA) in rats and assessment of aggrecan neoepitope release in synovial fluid using novel ELISAs. | 2010 | Osteoarthr. Cartil. | pmid:20633676 |
| Strassle BW et al. | Inhibition of osteoclasts prevents cartilage loss and pain in a rat model of degenerative joint disease. | 2010 | Osteoarthr. Cartil. | pmid:20633675 |
| Ochrietor JD et al. | The 2M6 antigen is a Müller cell-specific intracellular membrane-associated protein of the sarcolemmal-membrane-associated protein family and is also TopAP. | 2010 | Mol. Vis. | pmid:20577597 |
| Im HJ et al. | Alteration of sensory neurons and spinal response to an experimental osteoarthritis pain model. | 2010 | Arthritis Rheum. | pmid:20556813 |
| Castillo-Romero A et al. | Rab11 and actin cytoskeleton participate in Giardia lamblia encystation, guiding the specific vesicles to the cyst wall. | 2010 | PLoS Negl Trop Dis | pmid:20532229 |
| Ivannikov MV et al. | Calcium clearance and its energy requirements in cerebellar neurons. | 2010 | Cell Calcium | pmid:20510449 |
| Dalal P and Romani A | Adenosine triphosphate depletion by cyanide results in a Na(+)-dependent Mg(2+) extrusion from liver cells. | 2010 | Metab. Clin. Exp. | pmid:20494376 |
| Gigliobianco T et al. | Adenosine thiamine triphosphate accumulates in Escherichia coli cells in response to specific conditions of metabolic stress. | 2010 | BMC Microbiol. | pmid:20492686 |
| Tsai JH et al. | The protection of hepatocyte cells from the effects of oxidative stress by treatment with vitamin E in conjunction with DTT. | 2010 | J. Biomed. Biotechnol. | pmid:20490359 |
| González-Teuber M et al. | Glucanases and chitinases as causal agents in the protection of Acacia extrafloral nectar from infestation by phytopathogens. | 2010 | Plant Physiol. | pmid:20023149 |
| Okamoto M and Atsuta Y | Cartilage degeneration is associated with augmented chemically-induced joint pain in rats: a pilot study. | 2010 | Clin. Orthop. Relat. Res. | pmid:20013164 |
| Coombs PJ et al. | Identification of novel contributions to high-affinity glycoprotein-receptor interactions using engineered ligands. | 2010 | J. Mol. Biol. | pmid:20004209 |
| Sniekers YH et al. | Estrogen modulates iodoacetate-induced gene expression in bovine cartilage explants. | 2010 | J. Orthop. Res. | pmid:19953602 |
| North SJ et al. | Glycomics profiling of Chinese hamster ovary cell glycosylation mutants reveals N-glycans of a novel size and complexity. | 2010 | J. Biol. Chem. | pmid:19951948 |
| Chambers JE et al. | The reduction potential of the active site disulfides of human protein disulfide isomerase limits oxidation of the enzyme by Ero1α. | 2010 | J. Biol. Chem. | pmid:20657012 |
| Saudemont A et al. | Ancestral regulatory circuits governing ectoderm patterning downstream of Nodal and BMP2/4 revealed by gene regulatory network analysis in an echinoderm. | 2010 | PLoS Genet. | pmid:21203442 |
| Catterall JB et al. | Changes in serum and synovial fluid biomarkers after acute injury (NCT00332254). | 2010 | Arthritis Res. Ther. | pmid:21194441 |