Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Pain D010146 64 associated lipids
Lung Neoplasms D008175 171 associated lipids
Wounds and Injuries D014947 20 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Sarcoma 180 D012510 21 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Wei X et al. Drinking water disinfection byproduct iodoacetic acid induces tumorigenic transformation of NIH3T3 cells. 2013 Environ. Sci. Technol. pmid:23641915
Nan Y et al. Functional evaluation of iodoacetic acid induced photoreceptor degeneration in the cat. 2013 Sci China Life Sci pmid:23657794
More AS et al. Effect of iNOS inhibitor S-methylisothiourea in monosodium iodoacetate-induced osteoathritic pain: implication for osteoarthritis therapy. 2013 Pharmacol. Biochem. Behav. pmid:23287799
La Porta C et al. Role of CB1 and CB2 cannabinoid receptors in the development of joint pain induced by monosodium iodoacetate. 2013 Pain pmid:23199705
Wang XD et al. Estrogen aggravates iodoacetate-induced temporomandibular joint osteoarthritis. 2013 J. Dent. Res. pmid:23934157
Shao H et al. Intra-articular injection of xanthan gum reduces pain and cartilage damage in a rat osteoarthritis model. 2013 Carbohydr Polym pmid:23399228
Cialdai C et al. Comparison between oral and intra-articular antinociceptive effect of dexketoprofen and tramadol combination in monosodium iodoacetate-induced osteoarthritis in rats. 2013 Eur. J. Pharmacol. pmid:23891968
Pals J et al. Human cell toxicogenomic analysis linking reactive oxygen species to the toxicity of monohaloacetic acid drinking water disinfection byproducts. 2013 Environ. Sci. Technol. pmid:24050308
Dhaneshwar S and Patil D Chondromodulating chimeric prodrugs of diacetylrhein: synthesis and evaluation in monoiodoacetate-induced hyperalgesia. 2013 Med Chem pmid:22920092
Liu X et al. An optimized analytical method for the simultaneous detection of iodoform, iodoacetic acid, and other trihalomethanes and haloacetic acids in drinking water. 2013 PLoS ONE pmid:23613747
Barodka V et al. Nitroprusside inhibits calcium-induced impairment of red blood cell deformability. 2014 Transfusion pmid:23781865
Reinbold J et al. Quantitation of glutathione and its oxidation products in erythrocytes by multiple-label stable-isotope dilution. 2014 Anal. Biochem. pmid:24120409
van Buul GM et al. Mesenchymal stem cells reduce pain but not degenerative changes in a mono-iodoacetate rat model of osteoarthritis. 2014 J. Orthop. Res. pmid:24839120
Naveen SV et al. Histology, glycosaminoglycan level and cartilage stiffness in monoiodoacetate-induced osteoarthritis: comparative analysis with anterior cruciate ligament transection in rat model and human osteoarthritis. 2014 Int J Med Sci pmid:24396291
Tong P et al. Chondroprotective activity of a detoxicated traditional Chinese medicine (Fuzi) of Aconitum carmichaeli Debx against severe-stage osteoarthritis model induced by mono-iodoacetate. 2014 J Ethnopharmacol pmid:24315981
Brooke DG et al. Targeting the Warburg Effect in cancer; relationships for 2-arylpyridazinones as inhibitors of the key glycolytic enzyme 6-phosphofructo-2-kinase/2,6-bisphosphatase 3 (PFKFB3). 2014 Bioorg. Med. Chem. pmid:24398380
Sagar DR et al. Osteoprotegerin reduces the development of pain behaviour and joint pathology in a model of osteoarthritis. 2014 Ann. Rheum. Dis. pmid:23723320
Boudenot A et al. Effect of interval-training exercise on subchondral bone in a chemically-induced osteoarthritis model. 2014 Osteoarthr. Cartil. pmid:24928318
Lutas A et al. Metabolism regulates the spontaneous firing of substantia nigra pars reticulata neurons via KATP and nonselective cation channels. 2014 J. Neurosci. pmid:25471572
Procházka E et al. In Vitro Cytotoxicity and Adaptive Stress Responses to Selected Haloacetic Acid and Halobenzoquinone Water Disinfection Byproducts. 2015 Chem. Res. Toxicol. pmid:26327680