Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Pain D010146 64 associated lipids
Lung Neoplasms D008175 171 associated lipids
Wounds and Injuries D014947 20 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Sarcoma 180 D012510 21 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Osteoarthritis D010003 4 associated lipids
Coronary Disease D003327 70 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Glioma D005910 112 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Lymphoma D008223 18 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Brain Edema D001929 20 associated lipids
Stroke D020521 32 associated lipids
Starvation D013217 47 associated lipids
Hypocalcemia D006996 12 associated lipids
Brain Ischemia D002545 89 associated lipids
Epilepsy D004827 35 associated lipids
Nerve Degeneration D009410 53 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Hyperalgesia D006930 42 associated lipids
Thrombocytopenia D013921 15 associated lipids
Hyperlipidemias D006949 73 associated lipids
Rickets D012279 6 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
Byssinosis D002095 11 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Vitamin D Deficiency D014808 13 associated lipids
Vascular Diseases D014652 16 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Blindness D001766 6 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Temporomandibular Joint Disorders D013705 4 associated lipids
Arthralgia D018771 8 associated lipids
Osteophyte D054850 2 associated lipids
Glycogen Storage Disease D006008 4 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Retinitis D012173 4 associated lipids
Theileriasis D013801 7 associated lipids
Muscle Cramp D009120 3 associated lipids
Rigor Mortis D012298 1 associated lipids
Thrombophilia D019851 6 associated lipids
Cumulative Trauma Disorders D012090 2 associated lipids
Monckeberg Medial Calcific Sclerosis D050380 1 associated lipids
Clonorchiasis D003003 1 associated lipids
Osteoarthritis, Spine D055013 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Wei Y et al. Transient Receptor Potential Vanilloid 5 Mediates Ca2+ Influx and Inhibits Chondrocyte Autophagy in a Rat Osteoarthritis Model. 2017 Cell. Physiol. Biochem. pmid:28535500
McDougall JJ et al. Lysophosphatidic acid provides a missing link between osteoarthritis and joint neuropathic pain. 2017 Osteoarthr. Cartil. pmid:27651153
Thirunavukkarasu K et al. Identification and pharmacological characterization of a novel inhibitor of autotaxin in rodent models of joint pain. 2017 Osteoarthr. Cartil. pmid:27638130
Chiu PR et al. Vitamin C Protects Chondrocytes against Monosodium Iodoacetate-Induced Osteoarthritis by Multiple Pathways. 2016 Int J Mol Sci pmid:28035982
Yuan B et al. The Role of Glucose Metabolism on Porcine Oocyte Cytoplasmic Maturation and Its Possible Mechanisms. 2016 PLoS ONE pmid:27997591
Morais SV et al. Osteoarthritis model induced by intra-articular monosodium iodoacetate in rats knee. 2016 Acta Cir Bras pmid:27982265
Choi HS et al. Protective Effect of Deer Bone Oil on Cartilage Destruction in Rats with Monosodium Iodoacetate (MIA)-Induced Osteoarthritis. 2016 Biol. Pharm. Bull. pmid:27904047
Meesawatsom P et al. Inhibitory effects of aspirin-triggered resolvin D1 on spinal nociceptive processing in rat pain models. 2016 J Neuroinflammation pmid:27589850
Burston JJ et al. Robust anti-nociceptive effects of monoacylglycerol lipase inhibition in a model of osteoarthritis pain. 2016 Br. J. Pharmacol. pmid:27501482
Otis C et al. Concurrent validity of different functional and neuroproteomic pain assessment methods in the rat osteoarthritis monosodium iodoacetate (MIA) model. 2016 Arthritis Res. Ther. pmid:27338815