Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Rigor Mortis D012298 1 associated lipids
Monckeberg Medial Calcific Sclerosis D050380 1 associated lipids
Clonorchiasis D003003 1 associated lipids
Osteoarthritis, Spine D055013 2 associated lipids
Osteophyte D054850 2 associated lipids
Cumulative Trauma Disorders D012090 2 associated lipids
Muscle Cramp D009120 3 associated lipids
Retinitis D012173 4 associated lipids
Temporomandibular Joint Disorders D013705 4 associated lipids
Osteoarthritis D010003 4 associated lipids
Glycogen Storage Disease D006008 4 associated lipids
Blindness D001766 6 associated lipids
Rickets D012279 6 associated lipids
Thrombophilia D019851 6 associated lipids
Theileriasis D013801 7 associated lipids
Arthralgia D018771 8 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Byssinosis D002095 11 associated lipids
Hypocalcemia D006996 12 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Vitamin D Deficiency D014808 13 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Thrombocytopenia D013921 15 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Vascular Diseases D014652 16 associated lipids
Lymphoma D008223 18 associated lipids
Brain Edema D001929 20 associated lipids
Wounds and Injuries D014947 20 associated lipids
Sarcoma 180 D012510 21 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Stroke D020521 32 associated lipids
Burns D002056 34 associated lipids
Epilepsy D004827 35 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Hyperalgesia D006930 42 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Starvation D013217 47 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nerve Degeneration D009410 53 associated lipids
Pain D010146 64 associated lipids
Reperfusion Injury D015427 65 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Coronary Disease D003327 70 associated lipids
Hyperlipidemias D006949 73 associated lipids
Brain Ischemia D002545 89 associated lipids
Glioma D005910 112 associated lipids
Inflammation D007249 119 associated lipids
Hemolysis D006461 131 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Lung Neoplasms D008175 171 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Brooks WW et al. Comparative response of 2-week and 6-month old rat myocardium to hypoxia. 1985 J. Dev. Physiol. pmid:2864371
Nyberg F et al. Endopeptidase in human cerebrospinal fluid which cleaves proenkephalin B opioid peptides at consecutive basic amino acids. 1985 Biochem. Biophys. Res. Commun. pmid:2864927
Clegg JS and Gordon EP Respiratory metabolism of L-929 cells at different water contents and volumes. 1985 J. Cell. Physiol. pmid:4044656
Lehmann A et al. In vivo regulation of extracellular taurine and other neuroactive amino acids in the rabbit hippocampus. 1985 Prog. Clin. Biol. Res. pmid:2865739
Charbonneau H et al. Amino acid sequence of the calcium-dependent photoprotein aequorin. 1985 Biochemistry pmid:2866797
Tuominen RK Attempts to antagonize the effect of histamine on the cold-stimulated thyrotropin secretion in male rats. 1985 Acta Pharmacol Toxicol (Copenh) pmid:2868606
Griendling KK et al. Pregnancy-induced changes in sheep uterine and carotid arteries. 1985 Am. J. Physiol. pmid:2581458
Matsumoto B and Besharse JC Light and temperature modulated staining of the rod outer segment distal tips with Lucifer yellow. 1985 Invest. Ophthalmol. Vis. Sci. pmid:2581915
Chien KR et al. Release of arachidonate from membrane phospholipids in cultured neonatal rat myocardial cells during adenosine triphosphate depletion. Correlation with the progression of cell injury. 1985 J. Clin. Invest. pmid:3924955
Baskova IP and Nikonov GI [Destabilase: an enzyme of medicinal leech salivary gland secretion hydrolyzes the isopeptide bonds in stabilized fibrin]. 1985 Biokhimiia pmid:3922436
Grill V et al. Evidence that a "memory' for glucose metabolism desensitizes A-cell responsiveness in the perfused pancreas of the rat. 1985 Acta Endocrinol. pmid:2863914
Waheed A and Van Etten RL Sulfhydryl groups of rabbit liver arylsulfatase A. 1985 Biochim. Biophys. Acta pmid:2864083
Bosron WF et al. Purification and characterization of human liver beta 1 beta 1, beta 2 beta 2 and beta Ind beta Ind alcohol dehydrogenase isoenzymes. 1985 Prog. Clin. Biol. Res. pmid:3885259
Nakamura CE and Abeles RH Mode of interaction of beta-hydroxy-beta-methylglutaryl coenzyme A reductase with strong binding inhibitors: compactin and related compounds. 1985 Biochemistry pmid:3886005
Stewart LM et al. Energy coupling to K+ uptake via the Trk system in Escherichia coli: the role of ATP. 1985 J. Gen. Microbiol. pmid:3886836
Suzuki K et al. Mercuric and cadmium ions stimulate phosphorylation of band 4.2 protein on human erythrocyte membranes. 1985 J. Biol. Chem. pmid:2984208
Jura WG et al. Metabolic energy pathways in Theileria annulata sporozoites and their significance in sporozoite-bovine lymphocyte interactions in vitro. 1985 Vet. Parasitol. pmid:2986342
Chikuma T et al. Properties of Suc-GPLGP-MCAase and dipeptidyl-aminopeptidase in mouse calvaria-derived osteoblastic cells (MC3T3-E1). 1985 Calcif. Tissue Int. pmid:2988719
Seliuchenko OA et al. [Topography of cysteine residues in DNA-dependent RNA-polymerase]. 1985 Bioorg. Khim. pmid:3890863
Evans AC and Wilkinson KD Ubiquitin-dependent proteolysis of native and alkylated bovine serum albumin: effects of protein structure and ATP concentration on selectivity. 1985 Biochemistry pmid:2990536
Cox DW et al. Effects of metabolic inhibitors on evoked activity and the energy state of hippocampal slices superfused in vitro. 1985 Exp Brain Res pmid:2984037
Takaoka M et al. Activation of urinary inactive kallikrein by an extract from the rat kidney cortex. 1985 Life Sci. pmid:3897754
Necessary PC et al. Activity of alkylated prolactin and human growth hormone in receptor and cell assays. 1985 Mol. Cell. Endocrinol. pmid:2984068
Wakade AR et al. Sympathetic neurons extend neurites in a culture medium containing cyanide and dinitrophenol but not iodoacetate. 1985 FEBS Lett. pmid:3899726
Bagnasco S et al. Lactate production in isolated segments of the rat nephron. 1985 Am. J. Physiol. pmid:3985159
Tanaka K et al. Effect of iodoacetate on local cerebral blood flow and glucose metabolism in cats: a double-radionuclide autoradiographic study. 1985 J. Cereb. Blood Flow Metab. pmid:3988828
Plishker GA Iodoacetic acid inhibition of calcium-dependent potassium efflux in red blood cells. 1985 Am. J. Physiol. pmid:3993768
Heilmaier HE and Summer KH Metallothionein content and zinc status in various tissues of rats treated with iodoacetic acid and zinc. 1985 Arch. Toxicol. pmid:3994507
Fernandez-Luna JL et al. Complete amino acid sequence of the Aspergillus cytotoxin mitogillin. 1985 Biochemistry pmid:3994994
Holmes SD and Fairweather I Fasciola hepatica: motility response to metabolic inhibitors in vitro. 1985 Exp. Parasitol. pmid:3996521
Hardman MJ and Mills PH Carboxymethylated liver alcohol dehydrogenase: pH dependence of hydride transfer during ethanol oxidation. 1985 Biochim. Biophys. Acta pmid:2932159
Gottschalk WK and Sonneborn DR Evidence that Blastocladiella emersonii zoospore maintenance factor is a sulfhydryl group-containing cyclic ribotide. 1985 J. Biol. Chem. pmid:3997839
Sandberg M et al. Metabolically derived aspartate--elevated extracellular levels in vivo in lodoacetate poisoning. 1985 J. Neurosci. Res. pmid:4009740
Rispens P et al. Inhibition of carbonic anhydrase in dog plasma. 1985 Pflugers Arch. pmid:4011388
Busselen P Suppression of cellular injury during the calcium paradox in rat heart by factors which reduce calcium uptake by mitochondria. 1985 Pflugers Arch. pmid:4011406
Donadio S et al. Alkylation of amide linkages and cleavage of the C chain in the enzyme-activated-substrate inhibition of alpha-chymotrypsin with N-nitrosamides. 1985 Biochemistry pmid:4016069
Estrada P et al. Mechanism of the reaction catalyzed by acyl-CoA: lysolecithin acyltransferase from rabbit lung. pH studies and chemical modification. 1985 Int. J. Pept. Protein Res. pmid:4019033
Yeramian E et al. N-ethylmaleimide-induced changes in agonist affinity for histamine H1-receptors in the guinea pig brain. 1985 Mol. Pharmacol. pmid:4022000
Kostner GM et al. Altered metabolism of low density lipoprotein in humans after prolonged incubation in plasma. 1985 Clin. Sci. pmid:3971671
Unden G and Guest JR Isolation and characterization of the Fnr protein, the transcriptional regulator of anaerobic electron transport in Escherichia coli. 1985 Eur. J. Biochem. pmid:2981682
Connett RJ In vivo glycolytic equilibria in dog gracilis muscle. 1985 J. Biol. Chem. pmid:3972826
Weiss J and Hiltbrand B Functional compartmentation of glycolytic versus oxidative metabolism in isolated rabbit heart. 1985 J. Clin. Invest. pmid:3973013
Ursini F et al. The selenoenzyme phospholipid hydroperoxide glutathione peroxidase. 1985 Biochim. Biophys. Acta pmid:3978121
Pliszka B and Lu RC Reactivities of thiols in myosin rod: effect of magnesium and ionic strength. 1985 Biochim. Biophys. Acta pmid:4027253
Luchnik NV et al. [Effect of cell respiration inhibitors on the formation of structural mutations in human lymphocytes irradiated at different stages of the mitotic cycle]. 1985 Genetika pmid:4039281
Khowala S and Sengupta S Purification and properties of an endo-alpha-mannan hydrolase from the mushroom Volvariella volvacea. 1985 Arch. Biochem. Biophys. pmid:4041163
Gasanov GG et al. [Oscillatory evoked potentials in the rabbit visual system during experimental retinal pathology induced by administration of monoiodoacetic acid]. 1985 Biull Eksp Biol Med pmid:4041592
Cox CP and Quissell DO A novel platelet-activating protein derived from rat submandibular glands. 1985 Thromb. Res. pmid:4049321
Gibson DD et al. GSH-dependent inhibition of lipid peroxidation: properties of a potent cytosolic system which protects cell membranes. 1985 Lipids pmid:4058268
Mitchell DB et al. Role of glutathione depletion in the cytotoxicity of acetaminophen in a primary culture system of rat hepatocytes. 1985 Toxicology pmid:4060164
Williams JM and Brandt KD Triamcinolone hexacetonide protects against fibrillation and osteophyte formation following chemically induced articular cartilage damage. 1985 Arthritis Rheum. pmid:4063001
Wakade AR and Wakade TD Sympathetic neurons grown in culture generate ATP by glycolysis: correlation between ATP content and [3H]norepinephrine uptake and storage. 1985 Brain Res. pmid:4075161
Yamamoto K et al. Characteristics of activation of cathepsin B by sodium salicylate and comparison of catalytic site properties of cathepsins B and H. 1985 Jpn. J. Pharmacol. pmid:4087567
Beyer WF and Fridovich I Pseudocatalase from Lactobacillus plantarum: evidence for a homopentameric structure containing two atoms of manganese per subunit. 1985 Biochemistry pmid:4084532
Kuchel PW and Chapman BE Direct observation of the NAD glycohydrolase reaction in human erythrocytes using NMR spectroscopy. 1985 Experientia pmid:3155692
Ashiba G and Szent-Györgyi AG Essential light chain exchange in scallop myosin. 1985 Biochemistry pmid:4084545
Veselkina MN et al. [Effect of metabolic inhibitors on formed novocaine and neutral red segregation zones in frog erythrocytes]. 1985 Tsitologiia pmid:3159138
Williams JM and Brandt KD Benoxaprofen reduces osteophyte formation and fibrillation after articular cartilage injury. 1985 J. Rheumatol. pmid:3981515
Ientile R et al. The localization of phenolic and tyrosyl ring thyroxine deiodination in rat and mouse retina. 1985 Neurochem. Int. pmid:20493014
Kirley JW and Day RA Irreversible inhibition of carbonic anhydrase by the carbon dioxide analog cyanogen. 1985 Biochem. Biophys. Res. Commun. pmid:3918532
Plagemann PG et al. Adenine nucleotide metabolism and nucleoside transport in human erythrocytes under ATP depletion conditions. 1985 Biochim. Biophys. Acta pmid:3873962
MacArthur CA et al. Chemical carcinogens induce cadmium resistance and activate metallothionein genes in cadmium sensitive S49 mouse cells. 1985 Carcinogenesis pmid:3874005
Norris SH and Hersey SJ Stimulation of pepsinogen secretion in permeable isolated gastric glands. 1985 Am. J. Physiol. pmid:3876033
Shroyer LA and Varandani PT Purification and characterization of a rat liver cytosol neutral thiol peptidase that degrades glucagon, insulin, and isolated insulin A and B chains. 1985 Arch. Biochem. Biophys. pmid:3881083
Morgan MS et al. Participation of cellular thiol/disulphide groups in the uptake, degradation and bioactivity of insulin in primary cultures of rat hepatocytes. 1985 Biochem. J. pmid:3883990
Smith S et al. Mammalian fatty acid synthetase is a structurally and functionally symmetrical dimer. 1985 Eur. J. Biochem. pmid:3840436
Waqar MA et al. Phosphate uptake by primary renal proximal tubule cell cultures grown in hormonally defined medium. 1985 J. Cell. Physiol. pmid:3850091
Kindås-Mügge I and Sauermann G Transport of beta-globin mRNA from nuclei of murine Friend erythroleukemia cells. Reversible inhibition of transport by the oxidizing sulfhydryl reagent o-iodosobenzoate. 1985 Eur. J. Biochem. pmid:3856518
Chertov OIu et al. [The role of sulfhydryl groups in the functioning of DNA-dependent RNA-polymerase]. 1985 Bioorg. Khim. pmid:2408626
Buja LM et al. Alterations of ultrastructure and elemental composition in cultured neonatal rat cardiac myocytes after metabolic inhibition with iodoacetic acid. 1985 Lab. Invest. pmid:2413276
Poulose AJ et al. Cloning and sequencing of the cDNA for S-acyl fatty acid synthase thioesterase from the uropygial gland of mallard duck. 1985 J. Biol. Chem. pmid:2415525
Nakano K et al. [Studies on the relationship between the oxygen uptake and the release of amylase and sialic acid]. 1985 Nihon Seirigaku Zasshi pmid:2418200
Satoh S and Fujii T A membrane-bound protease in microsomes of spinach callus. 1985 Plant Physiol. pmid:16664228
Harrsch PB et al. Amino acid sequence similarity between spinach chloroplast and mammalian gluconeogenic fructose-1,6-bisphosphatase. 1985 Biochem. Biophys. Res. Commun. pmid:3002349
Montanaro L et al. A metalloproteinase associated with gelonin, a "ribosome inactivating protein". 1985 Jan-Feb Ital. J. Biochem. pmid:3924857
Bühler R et al. Human liver alcohol dehydrogenase: the unique properties of the "atypical" isoenzyme beta 2 beta 2-Bern can be explained by a single base mutation. 1985 Jan-Feb Alcohol pmid:3893464
Kalbhen DA [Orienting animal experiment studies on the effect of fenbufen on healthy and arthrosis-induced articular cartilage tissue in vivo]. 1985 Jul-Aug Z Rheumatol pmid:4050149
Buchmann U and Kalbhen DA [Experimental gonarthrosis in rats and its therapy with glycosaminoglycan polysulfate (GAGPS)]. 1985 May-Jun Z Rheumatol pmid:4060902
DiMattio J and Streitman J Facilitated glucose transport across the retinal pigment epithelium of the bullfrog (Rana catesbeiana). 1986 Exp. Eye Res. pmid:3525201
Turkiewicz M et al. Purification and characterization of a proteinase from Euphausia superba Dana (Antarctic krill). 1986 Acta Biochim. Pol. pmid:3532651
Plishker GA et al. Involvement of a cytoplasmic protein in calcium-dependent potassium efflux in red blood cells. 1986 Am. J. Physiol. pmid:3532815
Hilf R et al. Relationship of mitochondrial function and cellular adenosine triphosphate levels to hematoporphyrin derivative-induced photosensitization in R3230AC mammary tumors. 1986 Cancer Res. pmid:3940191
Bosron WF et al. Selective carboxymethylation of cysteine-174 of the beta 2 beta 2 and beta 1 beta 1 human liver alcohol dehydrogenase isoenzymes by iodoacetate. 1986 Biochemistry pmid:2939875
LaNoue KF et al. Regulation of Na+ transport in brown adipose tissue. 1986 Biochem. J. pmid:2943272
Zeidan HM et al. Microenvironment around the essential cysteine residues in chicken liver fructose-1,6-bisphosphatase as analyzed by ESR spin labelling. 1986 Biochim. Biophys. Acta pmid:3004586
Horton JK et al. Paraquat uptake into freshly isolated rabbit lung epithelial cells and its reduction to the paraquat radical under anaerobic conditions. 1986 Mol. Pharmacol. pmid:3010076
Mitra G and Ng PK Hepatitis B virus associated DNA polymerase inactivation in factor IX concentrates. 1986 Thromb. Res. pmid:3705011
Engberg P and Lindskog S Activation of bovine muscle carbonic anhydrase by modification of thiol groups. 1986 Eur. J. Biochem. pmid:3084253
Bergenhem N et al. The existence of glutathione and cysteine disulfide-linked to erythrocyte carbonic anhydrase from tiger shark. 1986 Biochim. Biophys. Acta pmid:3083866
Vander Heide RS et al. Energy dependence of contraction band formation in perfused hearts and isolated adult myocytes. 1986 Am. J. Pathol. pmid:3777140
Suzuki H [Heme transport from mitochondria to apocytochrome b5 incorporated into phospholipid vesicles by cytosolic liver protein]. 1986 Hokkaido Igaku Zasshi pmid:3781470
Brandau DT et al. The effect of interchain disulfide bond cleavage on the cold induced precipitation of cryoimmunoglobulins. 1986 Immunol. Invest. pmid:3781575
Song KB et al. Requirement for a sulfhydryl group for sulfhydryl oxidase activity. 1986 J. Dairy Sci. pmid:3805443
Yamato S et al. Spectrophotometric determination of inorganic phosphate in the presence of thiol compounds. 1986 Anal. Biochem. pmid:3812971
Sayeed MM Alterations in cellular Ca2+ regulation in the liver in endotoxic shock. 1986 Am. J. Physiol. pmid:3706573
Suzuki R et al. [Divalent chelating agents, calcium blockers and metabolic inhibitors had different effects on the iris sphincter muscles]. 1986 Nippon Ganka Gakkai Zasshi pmid:3716941
Liotti FS and Locci P Onset and growth rate of solid tumours derived from implanted ascites tumour cells pretreated with ascorbic acid. 1986 Boll Ist Sieroter Milan pmid:3718681
Ishiura S et al. Ingensin, a fatty acid-activated serine proteinase from rat liver cytosol. 1986 Biochim. Biophys. Acta pmid:3524690
Olesen SP Rapid increase in blood-brain barrier permeability during severe hypoxia and metabolic inhibition. 1986 Brain Res. pmid:3485464
Gilbert SH and Ford LE The thermoelastic effect in rigor muscle of the frog. 1986 J. Muscle Res. Cell. Motil. pmid:3485655