Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Wang YC et al. | Intracellular Na(+) and metabolic modulation of Na/K pump and excitability in the rat suprachiasmatic nucleus neurons. | 2012 | J. Neurophysiol. | pmid:22773774 |
Wang XD et al. | Progression of cartilage degradation, bone resorption and pain in rat temporomandibular joint osteoarthritis induced by injection of iodoacetate. | 2012 | PLoS ONE | pmid:22984604 |
Lee JH et al. | Alteration patterns of trabecular bone microarchitectural characteristics induced by osteoarthritis over time. | 2012 | Clin Interv Aging | pmid:22956865 |
Moon SJ et al. | Rebamipide attenuates pain severity and cartilage degeneration in a rat model of osteoarthritis by downregulating oxidative damage and catabolic activity in chondrocytes. | 2012 | Osteoarthr. Cartil. | pmid:22890185 |
Downs I et al. | The ROS scavenger, NAC, regulates hepatic Vα14iNKT cells signaling during Fas mAb-dependent fulminant liver failure. | 2012 | PLoS ONE | pmid:22701598 |
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Izumi M et al. | RBCS1A and RBCS3B, two major members within the Arabidopsis RBCS multigene family, function to yield sufficient Rubisco content for leaf photosynthetic capacity. | 2012 | J. Exp. Bot. | pmid:22223809 |
Fiaschi T et al. | Redox Regulation of Nonmuscle Myosin Heavy Chain during Integrin Engagement. | 2012 | J Signal Transduct | pmid:22220276 |
Vincent A et al. | parkin-induced defects in neurophysiology and locomotion are generated by metabolic dysfunction and not oxidative stress. | 2012 | Hum. Mol. Genet. | pmid:22215442 |
Egger S et al. | Structural and kinetic evidence that catalytic reaction of human UDP-glucose 6-dehydrogenase involves covalent thiohemiacetal and thioester enzyme intermediates. | 2012 | J. Biol. Chem. | pmid:22123821 |
Ford AP | In pursuit of P2X3 antagonists: novel therapeutics for chronic pain and afferent sensitization. | 2012 | Purinergic Signal. | pmid:22095157 |
North SJ et al. | Glycomic analysis of human mast cells, eosinophils and basophils. | 2012 | Glycobiology | pmid:21725073 |
Reyes-FermÃn LM et al. | Neuroprotective effect of α-mangostin and curcumin against iodoacetate-induced cell death. | 2012 | Nutr Neurosci | pmid:22776704 |
Ferreira-Gomes J et al. | Dose-dependent expression of neuronal injury markers during experimental osteoarthritis induced by monoiodoacetate in the rat. | 2012 | Mol Pain | pmid:22769424 |
Noel JM et al. | Iodoacetic acid, but not sodium iodate, creates an inducible swine model of photoreceptor damage. | 2012 | Exp. Eye Res. | pmid:22251455 |
Hardes K et al. | Design, synthesis, and characterization of chromogenic substrates of coagulation factor XIIIa. | 2012 | Anal. Biochem. | pmid:22683584 |
Rao Y et al. | Mapping of sulfur metabolic pathway by LC Orbitrap mass spectrometry. | 2012 | Anal. Chim. Acta | pmid:22405311 |