Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
pmid:12297233 | ||||
Jung J et al. | Interaction of cofilin with triose-phosphate isomerase contributes glycolytic fuel for Na,K-ATPase via Rho-mediated signaling pathway. | 2002 | J. Biol. Chem. | pmid:12359716 |
Zeppezauer E et al. | Carboxymethylation of horse-liver alcohol dehydrogenase in the crystalline state. The active-site zinc region and general anion-binding site of the enzyme correlated in primary and teritiary structures. | 1975 | Eur. J. Biochem. | pmid:1237402 |
Parkinson AJ and Kalmakoff J | Tritium labeling of immunoglobulin with iodoacetic acid. | 1975 Jun-Jul | Int J Appl Radiat Isot | pmid:1237470 |
pmid:12384169 | ||||
Peral MJ et al. | Human, rat and chicken small intestinal Na+ - Cl- -creatine transporter: functional, molecular characterization and localization. | 2002 | J. Physiol. (Lond.) | pmid:12433955 |
pmid:12435144 | ||||
Fonda ML | Bromopyruvate inactivation of glutamate apodecarboxylase. Kinetics and specificity. | 1976 | J. Biol. Chem. | pmid:1244350 |
Luchnik NV | [Phenomenon of pseudomutagenesis: experiments with modifiers of cell metabolism in human lymphocytes]. | 2002 | Genetika | pmid:12449644 |
Kuo SC and Lampen JO | Action of cytochalasin A, a sulfhydryl-reactive agent, on sugar metabolism and membrane-bound adenosine triphosphatase of yeast. | 1975 | Biochim. Biophys. Acta | pmid:124588 |
Ghelis C et al. | The conformational oscillation of delta-chymotrypsin involvement of methionine-192. | 1975 | Eur. J. Biochem. | pmid:1247 |
Ikemoto A et al. | Glycolysis and glutamate accumulation into synaptic vesicles. Role of glyceraldehyde phosphate dehydrogenase and 3-phosphoglycerate kinase. | 2003 | J. Biol. Chem. | pmid:12488440 |
Espelt MV et al. | Volumetric and ionic responses of goldfish hepatocytes to anisotonic exposure and energetic limitation. | 2003 | J. Exp. Biol. | pmid:12502772 |
Kito Y and Suzuki H | Pacemaker frequency is increased by sodium nitroprusside in the guinea pig gastric antrum. | 2003 | J. Physiol. (Lond.) | pmid:12509488 |
Müller M and Ballanyi K | Dynamic recording of cell death in the in vitro dorsal vagal nucleus of rats in response to metabolic arrest. | 2003 | J. Neurophysiol. | pmid:12522201 |
Damon BM et al. | The carnosine C-2 proton's chemical shift reports intracellular pH in oxidative and glycolytic muscle fibers. | 2003 | Magn Reson Med | pmid:12541242 |
Di-Capua N et al. | Protein kinase C-epsilon is involved in the adenosine-activated signal transduction pathway conferring protection against ischemia-reperfusion injury in primary rat neuronal cultures. | 2003 | J. Neurochem. | pmid:12559003 |
pmid:12559101 | ||||
Phillips ER and Perdue JF | The expression and localization of surface neoantigens in transformed and untransformed cultured cells infected with avian tumor viruses. | 1976 | J. Supramol. Struct. | pmid:1256061 |
pmid:12565709 | ||||
Newcomb LL et al. | Glucose regulation of Saccharomyces cerevisiae cell cycle genes. | 2003 | Eukaryotic Cell | pmid:12582131 |
Gupta SR et al. | Effect of some inhibitors on aflatoxin-production in a synthetic medium and on the incorporation of acetate-1- 14C into aflatoxins by resting mycelia of Aspergillus parasiticus. | 1976 | Bull Environ Contam Toxicol | pmid:1260151 |
Scarpace PJ and Neuman WF | The blood: bone disequilibrium. I. The active accumulation of K+ into the bone extracellular fluid. | 1976 | Calcif Tissue Res | pmid:1260484 |
Scarpace PJ and Neuman WF | The blood: bone disequilibrium. II. Evidence against the active accumulation of calcium or phosphate into the bone extracellular fluid. | 1976 | Calcif Tissue Res | pmid:1260485 |
Battista N et al. | Anandamide uptake by synaptosomes from human, mouse and rat brain: inhibition by glutamine and glutamate. | 2002 | Lipids Health Dis | pmid:12617751 |
Ito K et al. | Novel aminopeptidase specific for glycine from Actinomucor elegans. | 2003 | Biosci. Biotechnol. Biochem. | pmid:12619677 |
Jensen JB and Edgar SA | Effects of antiphagocytic agents on penetration of Eimeria magna sporozoites into cultured cells. | 1976 | J. Parasitol. | pmid:1263027 |
Harrison GJ et al. | Glycolytic buffering affects cardiac bioenergetic signaling and contractile reserve similar to creatine kinase. | 2003 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12714331 |
Wentzel P et al. | Maternal diabetes in vivo and high glucose in vitro diminish GAPDH activity in rat embryos. | 2003 | Diabetes | pmid:12716756 |
Winkler BS et al. | Modulation of the Pasteur effect in retinal cells: implications for understanding compensatory metabolic mechanisms. | 2003 | Exp. Eye Res. | pmid:12742354 |
Mori M | A study on the nuclear extrusion of mammalian erythroblast. | 1975 | Acta Med. Okayama | pmid:127510 |
pmid:12760417 | ||||
Dayton WR et al. | A Ca2+-activated protease possibly involved in myofibrillar protein turnover. Partial characterization of the purified enzyme. | 1976 | Biochemistry | pmid:1276131 |
pmid:12770769 | ||||
Hallak GJ and Wilkinson JH | Membrane permeability in normal human lymphocytes and lymphocytes from patients with chronic lymphatic leukaemia. | 1976 | Clin. Chim. Acta | pmid:1277564 |
Buckel W | Acetic anhydride: an intermediate analogue in the acyl-exchange reaction of citramalate lyase. | 1976 | Eur. J. Biochem. | pmid:1278157 |
Zolotova VF et al. | [Sodium release from tissue paracellular space under the influence of angiotensin II]. | 1976 | Fiziol Zh SSSR Im I M Sechenova | pmid:1278538 |
pmid:12787820 | ||||
Bárány M et al. | Structural changes in myosin during contraction and the state of ATP in the intact frog muscle. | 1975 | J. Supramol. Struct. | pmid:127883 |
Lucas J et al. | Susceptibility of myelin proteins to a neutral endoproteinase: the degradation of myelin basic protein (MBP) and P2 protein by purified bovine brain multicatalytic proteinase complex (MPC). | 1992 | Neurochem. Res. | pmid:1281293 |
Maekawa Y et al. | A tetrazolium-based colorimetric assay for metabolic activity of stored blood platelets. | 2003 | Thromb. Res. | pmid:12818255 |
Flanagan PR and Zbarsky SH | Rat intestinal phosphodiesterase II. Properties of the highly purified enzyme and its inactivation by iodoacetic acid. | 1977 | Biochim. Biophys. Acta | pmid:12824 |
Kim YJ | Partial inhibition of biohydrogenation of linoleic acid can increase the conjugated linoleic acid production of Butyrivibrio fibrisolvens A38. | 2003 | J. Agric. Food Chem. | pmid:12848494 |
Ding PZ | An investigation of cysteine mutants on the cytoplasmic loop X/XI in the melibiose transporter of Escherichia coli by using thiol reagents: implication of structural conservation of charged residues. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12878191 |
pmid:12882641 | ||||
Massieu L et al. | Acetoacetate protects hippocampal neurons against glutamate-mediated neuronal damage during glycolysis inhibition. | 2003 | Neuroscience | pmid:12890508 |
pmid:12892929 | ||||
Bürkert E et al. | The C2-like beta-barrel domain mediates the Ca2+-dependent resistance of 5-lipoxygenase activity against inhibition by glutathione peroxidase-1. | 2003 | J. Biol. Chem. | pmid:12893830 |
Chen X et al. | [Detection of proteolytic activity of hepatitis C virus NS3-4A protease using enzymelinked immunosorbent assay]. | 2000 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:12903484 |
Vera PL and Meyer-Siegler KL | Anatomical location of macrophage migration inhibitory factor in urogenital tissues, peripheral ganglia and lumbosacral spinal cord of the rat. | 2003 | BMC Neurosci | pmid:12908877 |