Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Osteoarthritis, Spine D055013 2 associated lipids
Osteophyte D054850 2 associated lipids
Monckeberg Medial Calcific Sclerosis D050380 1 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Stroke D020521 32 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Thrombophilia D019851 6 associated lipids
Arthralgia D018771 8 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Reperfusion Injury D015427 65 associated lipids
Wounds and Injuries D014947 20 associated lipids
Vitamin D Deficiency D014808 13 associated lipids
Vascular Diseases D014652 16 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Thrombocytopenia D013921 15 associated lipids
Theileriasis D013801 7 associated lipids
Temporomandibular Joint Disorders D013705 4 associated lipids
Starvation D013217 47 associated lipids
Sarcoma 180 D012510 21 associated lipids
Rigor Mortis D012298 1 associated lipids
Rickets D012279 6 associated lipids
Retinitis D012173 4 associated lipids
Cumulative Trauma Disorders D012090 2 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Pain D010146 64 associated lipids
Osteoarthritis D010003 4 associated lipids
Nerve Degeneration D009410 53 associated lipids
Muscle Cramp D009120 3 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Lymphoma D008223 18 associated lipids
Lung Neoplasms D008175 171 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Inflammation D007249 119 associated lipids
Hypocalcemia D006996 12 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hyperalgesia D006930 42 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
Glycogen Storage Disease D006008 4 associated lipids
Glioma D005910 112 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Epilepsy D004827 35 associated lipids
Coronary Disease D003327 70 associated lipids
Clonorchiasis D003003 1 associated lipids
Brain Ischemia D002545 89 associated lipids
Byssinosis D002095 11 associated lipids
Burns D002056 34 associated lipids
Brain Edema D001929 20 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
Blindness D001766 6 associated lipids
Arthritis, Experimental D001169 24 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Moreau M et al. Tiludronate treatment improves structural changes and symptoms of osteoarthritis in the canine anterior cruciate ligament model. 2011 Arthritis Res. Ther. pmid:21693018
Dionisio G et al. Cloning and characterization of purple acid phosphatase phytases from wheat, barley, maize, and rice. 2011 Plant Physiol. pmid:21220762
Plewa MJ et al. Mammalian cell cytotoxicity and genotoxicity of the haloacetic acids, a major class of drinking water disinfection by-products. 2010 Oct-Dec Environ. Mol. Mutagen. pmid:20839218
Zhu Y et al. Differential gene expression in mouse retina related to regional differences in vulnerability to hyperoxia. 2010 Mol. Vis. pmid:20454693
Rodríguez E et al. Uncoupling oxidative/energy metabolism with low sub chronic doses of 3-nitropropionic acid or iodoacetate in vivo produces striatal cell damage. 2010 Int. J. Biol. Sci. pmid:20440403
Larriba MJ et al. Novel snail1 target proteins in human colon cancer identified by proteomic analysis. 2010 PLoS ONE pmid:20421926
Cifuentes DJ et al. Decrease in oxidative stress and histological changes induced by physical exercise calibrated in rats with osteoarthritis induced by monosodium iodoacetate. 2010 Osteoarthr. Cartil. pmid:20417294
Bloom HL et al. Statins Decrease Oxidative Stress and ICD Therapies. 2010 Cardiol Res Pract pmid:20369058
Xu S et al. Transport of L-carnitine in human corneal and conjunctival epithelial cells. 2010 Mol. Vis. pmid:21045919
Brumshtein B et al. Characterization of gene-activated human acid-beta-glucosidase: crystal structure, glycan composition, and internalization into macrophages. 2010 Glycobiology pmid:19741058
Liviac D et al. Genotoxicity testing of three monohaloacetic acids in TK6 cells using the cytokinesis-block micronucleus assay. 2010 Mutagenesis pmid:20547559
Hall AM et al. Albumin uptake in OK cells exposed to rotenone: a model for studying the effects of mitochondrial dysfunction on endocytosis in the proximal tubule? 2010 Nephron Physiol pmid:20484937
Nagarathnam R et al. Purification and properties of cysteine protease from rhizomes of Curcuma longa (Linn.). 2010 J. Sci. Food Agric. pmid:20355018
Yang D et al. Impairment of mitochondrial respiration in mouse fibroblasts by oncogenic H-RAS(Q61L). 2010 Cancer Biol. Ther. pmid:19923925
Sarigianni M et al. Involvement of signaling molecules on na/h exchanger-1 activity in human monocytes. 2010 Open Cardiovasc Med J pmid:21160910
Gupta K et al. Identification, activity and disulfide connectivity of C-di-GMP regulating proteins in Mycobacterium tuberculosis. 2010 PLoS ONE pmid:21151497
Tavender TJ et al. Recycling of peroxiredoxin IV provides a novel pathway for disulphide formation in the endoplasmic reticulum. 2010 EMBO J. pmid:21057456
Iyer SS et al. Effect of bone marrow-derived mesenchymal stem cells on endotoxin-induced oxidation of plasma cysteine and glutathione in mice. 2010 Stem Cells Int pmid:21048855
Madry C et al. The role of pannexin hemichannels in the anoxic depolarization of hippocampal pyramidal cells. 2010 Brain pmid:20940167
Peyfoon E et al. The S-layer glycoprotein of the crenarchaeote Sulfolobus acidocaldarius is glycosylated at multiple sites with chitobiose-linked N-glycans. 2010 Archaea pmid:20936123