Iodoacetic acid
Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
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Introduction
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Iodoacetic acid?
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
PubChem Associated disorders and diseases
What pathways are associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Iodoacetic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
What functions are associated with Iodoacetic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Iodoacetic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Iodoacetic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Maekawa Y et al. | A tetrazolium-based colorimetric assay for metabolic activity of stored blood platelets. | 2003 | Thromb. Res. | pmid:12818255 |
| Flanagan PR and Zbarsky SH | Rat intestinal phosphodiesterase II. Properties of the highly purified enzyme and its inactivation by iodoacetic acid. | 1977 | Biochim. Biophys. Acta | pmid:12824 |
| Kim YJ | Partial inhibition of biohydrogenation of linoleic acid can increase the conjugated linoleic acid production of Butyrivibrio fibrisolvens A38. | 2003 | J. Agric. Food Chem. | pmid:12848494 |
| Ding PZ | An investigation of cysteine mutants on the cytoplasmic loop X/XI in the melibiose transporter of Escherichia coli by using thiol reagents: implication of structural conservation of charged residues. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12878191 |
| pmid:12882641 | ||||
| Massieu L et al. | Acetoacetate protects hippocampal neurons against glutamate-mediated neuronal damage during glycolysis inhibition. | 2003 | Neuroscience | pmid:12890508 |
| pmid:12892929 | ||||
| Bürkert E et al. | The C2-like beta-barrel domain mediates the Ca2+-dependent resistance of 5-lipoxygenase activity against inhibition by glutathione peroxidase-1. | 2003 | J. Biol. Chem. | pmid:12893830 |
| Chen X et al. | [Detection of proteolytic activity of hepatitis C virus NS3-4A protease using enzymelinked immunosorbent assay]. | 2000 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:12903484 |
| Vera PL and Meyer-Siegler KL | Anatomical location of macrophage migration inhibitory factor in urogenital tissues, peripheral ganglia and lumbosacral spinal cord of the rat. | 2003 | BMC Neurosci | pmid:12908877 |
| Tůmová L et al. | [Iodoacetic acid as a potential elicitor of increased production of flavonoids in a culture of Ononis arvensis L. in vitro]. | 2003 | Ceska Slov Farm | pmid:12924071 |
| pmid:12952458 | ||||
| Rosenthal M and Sick TJ | Glycolytic and oxidative metabolic contributions to potassium ion transport in rat cerebral cortex. | 1992 | Can. J. Physiol. Pharmacol. | pmid:1295667 |
| EBE M | Effect of glutamic acid, NaCN and monoiodoacetic acid on the potential changes of isolated toad's brain. | 1952 | Tohoku J. Exp. Med. | pmid:13005477 |
| Hruz PW and Miziorko HM | Avian 3-hydroxy-3-methylglutaryl-CoA lyase: sensitivity of enzyme activity to thiol/disulfide exchange and identification of proximal reactive cysteines. | 1992 | Protein Sci. | pmid:1304393 |
| Xia Y et al. | Oxidative and glycolytic pathways in rat (newborn and adult) and turtle brain: role during anoxia. | 1992 | Am. J. Physiol. | pmid:1314516 |
| Stinson MW et al. | Inhibition of Porphyromonas gingivalis adhesion to Streptococcus gordonii by human submandibular-sublingual saliva. | 1992 | Infect. Immun. | pmid:1319402 |
| Rae AS and Strickland KP | Studies on phosphate transport in Escherichia coli. II. Effects of metabolic inhibitors and divalent cations. | 1976 | Biochim. Biophys. Acta | pmid:132192 |
| Knowles MR et al. | Bovine inositol monophosphatase. Modification, identification and mutagenesis of reactive cysteine residues. | 1992 | Biochem. J. | pmid:1322134 |
| pmid:13248903 |