Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Osteoarthritis, Spine D055013 2 associated lipids
Osteophyte D054850 2 associated lipids
Monckeberg Medial Calcific Sclerosis D050380 1 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Stroke D020521 32 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Thrombophilia D019851 6 associated lipids
Arthralgia D018771 8 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Reperfusion Injury D015427 65 associated lipids
Wounds and Injuries D014947 20 associated lipids
Vitamin D Deficiency D014808 13 associated lipids
Vascular Diseases D014652 16 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Thrombocytopenia D013921 15 associated lipids
Theileriasis D013801 7 associated lipids
Temporomandibular Joint Disorders D013705 4 associated lipids
Starvation D013217 47 associated lipids
Sarcoma 180 D012510 21 associated lipids
Rigor Mortis D012298 1 associated lipids
Rickets D012279 6 associated lipids
Retinitis D012173 4 associated lipids
Cumulative Trauma Disorders D012090 2 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Pain D010146 64 associated lipids
Osteoarthritis D010003 4 associated lipids
Nerve Degeneration D009410 53 associated lipids
Muscle Cramp D009120 3 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Lymphoma D008223 18 associated lipids
Lung Neoplasms D008175 171 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Inflammation D007249 119 associated lipids
Hypocalcemia D006996 12 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hyperalgesia D006930 42 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
Glycogen Storage Disease D006008 4 associated lipids
Glioma D005910 112 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Epilepsy D004827 35 associated lipids
Coronary Disease D003327 70 associated lipids
Clonorchiasis D003003 1 associated lipids
Brain Ischemia D002545 89 associated lipids
Byssinosis D002095 11 associated lipids
Burns D002056 34 associated lipids
Brain Edema D001929 20 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
Blindness D001766 6 associated lipids
Arthritis, Experimental D001169 24 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Shi H and Adams C Rapid IC-ICP/MS method for simultaneous analysis of iodoacetic acids, bromoacetic acids, bromate, and other related halogenated compounds in water. 2009 Talanta pmid:19559915
Rogers DW et al. Transglutaminase-mediated semen coagulation controls sperm storage in the malaria mosquito. 2009 PLoS Biol. pmid:20027206
Harvey VL and Dickenson AH Behavioural and electrophysiological characterisation of experimentally induced osteoarthritis and neuropathy in C57Bl/6 mice. 2009 Mol Pain pmid:19379487
Nochez Y et al. Acute and late-onset optic atrophy due to a novel OPA1 mutation leading to a mitochondrial coupling defect. 2009 Mol. Vis. pmid:19325939
Gandhi S et al. PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death. 2009 Mol. Cell pmid:19285945
Shani V et al. Involvement of Src tyrosine kinases (SFKs) and of focal adhesion kinase (FAK) in the injurious mechanism in rat primary neuronal cultures exposed to chemical ischemia. 2009 J. Mol. Neurosci. pmid:18584337
Pilarski JQ et al. Effects of aerobic and anaerobic metabolic inhibitors on avian intrapulmonary chemoreceptors. 2009 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:19297545
Huisamen B et al. Signalling pathways activated by glucagon-like peptide-1 (7-36) amide in the rat heart and their role in protection against ischaemia. 2008 Mar-Apr Cardiovasc J Afr pmid:18516352
Liang L et al. Long-term cellular and regional specificity of the photoreceptor toxin, iodoacetic acid (IAA), in the rabbit retina. 2008 Mar-Apr Vis. Neurosci. pmid:18442439
Gilge JL et al. The effect of oxidant and the non-oxidant alteration of cellular thiol concentration on the formation of protein mixed-disulfides in HEK 293 cells. 2008 PLoS ONE pmid:19107210
Weiner RM et al. Complete genome sequence of the complex carbohydrate-degrading marine bacterium, Saccharophagus degradans strain 2-40 T. 2008 PLoS Genet. pmid:18516288
Rudrappa T et al. Cyanogenic pseudomonads influence multitrophic interactions in the rhizosphere. 2008 PLoS ONE pmid:18446201
Otis JS et al. Effect of HIV-1-related protein expression on cardiac and skeletal muscles from transgenic rats. 2008 AIDS Res Ther pmid:18439274
Piscaer TM et al. In vivo imaging of cartilage degeneration using microCT-arthrography. 2008 Osteoarthr. Cartil. pmid:18342549
Duan X et al. Proteomic analysis of aqueous humor from patients with myopia. 2008 Mol. Vis. pmid:18334949
Shiratani T et al. Crystalline lens changes in porcine eyes with implanted phakic IOL (ICL) with a central hole. 2008 Graefes Arch. Clin. Exp. Ophthalmol. pmid:18299877
Ingram KR et al. Cyclic movement stimulates hyaluronan secretion into the synovial cavity of rabbit joints. 2008 J. Physiol. (Lond.) pmid:18202097
Koufany M et al. Anti-inflammatory effect of antidiabetic thiazolidinediones prevents bone resorption rather than cartilage changes in experimental polyarthritis. 2008 Arthritis Res. Ther. pmid:18199331
Richardson SD et al. Occurrence and mammalian cell toxicity of iodinated disinfection byproducts in drinking water. 2008 Environ. Sci. Technol. pmid:19068814
Nakamura K et al. Detoxification system for inorganic arsenic: transformation of As2O3 into TMAO by vitamin B12 derivatives and conversion of TMAO into arsenobetaine. 2008 Chem. Commun. (Camb.) pmid:18956042