Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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David M et al. | Studies of glutamate dehydrogenase. Methionine-169: the preferentially carboxymethylated residue. | 1977 | Eur. J. Biochem. | pmid:15838 |
pmid:15837310 | ||||
Wood JP et al. | Energy substrate requirements for survival of rat retinal cells in culture: the importance of glucose and monocarboxylates. | 2005 | J. Neurochem. | pmid:15836627 |
pmid:15820130 | ||||
pmid:15817784 | ||||
Morty RE et al. | Identification of the reactive cysteine residues in oligopeptidase B from Trypanosoma brucei. | 2005 | FEBS Lett. | pmid:15811340 |
Chapman JC et al. | Mitochondrial 3 beta-hydroxysteroid dehydrogenase (HSD) is essential for the synthesis of progesterone by corpora lutea: an hypothesis. | 2005 | Reprod. Biol. Endocrinol. | pmid:15804366 |
pmid:15801027 | ||||
Falchi AM et al. | Characterization of depolarization and repolarization phases of mitochondrial membrane potential fluctuations induced by tetramethylrhodamine methyl ester photoactivation. | 2005 | FEBS J. | pmid:15794752 |
Günzel D et al. | Mg2+-malate co-transport, a mechanism for Na+-independent Mg2+ transport in neurons of the leech Hirudo medicinalis. | 2005 | J. Neurophysiol. | pmid:15788520 |
pmid:15777859 | ||||
Liu SQ et al. | Carboxymethylation-induced activation of bovine lens aldose reductase. | 1992 | Biochim. Biophys. Acta | pmid:1576159 |
Perez E et al. | Neuroprotective effects of an estratriene analog are estrogen receptor independent in vitro and in vivo. | 2005 | Brain Res. | pmid:15757637 |
Brecht M et al. | Late steady increase in cytosolic Ca2+ preceding hypoxic injury in hepatocytes. | 1992 | Biochem. J. | pmid:1575684 |
pmid:15750682 | ||||
Garfield RE and Daniel EE | Relation of membrane vesicles to volume and Na+ transport in smooth muscle: effect of metabolic and transport inhibition on fresh tissues. | 1977 | J Mechanochem Cell Motil | pmid:157383 |
Shu W et al. | [Study of preparation methods of polyclonal antibody of chymopapain]. | 2004 | Wei Sheng Yan Jiu | pmid:15727194 |
Choi SJ et al. | Effect of ketamine on apoptosis by energy deprivation in astroglioma cells using flow cytometry system. | 2005 | J. Korean Med. Sci. | pmid:15716615 |
Chi CH and Dixit BN | Characterization of (+/-)-methadone uptake by rat lung. | 1977 | Br. J. Pharmacol. | pmid:15696 |
Kockskämper J et al. | Modulation of sarcoplasmic reticulum Ca2+ release by glycolysis in cat atrial myocytes. | 2005 | J. Physiol. (Lond.) | pmid:15695247 |
pmid:15652186 | ||||
pmid:15645293 | ||||
Wilkinson JH et al. | Factors affecting the release of haemoglobin and enzymes from human erythrocytes. | 1975 | Ann. Clin. Biochem. | pmid:15637925 |
Winmill RE et al. | Development of the respiratory response to hypoxia in the isolated brainstem of the bullfrog Rana catesbeiana. | 2005 | J. Exp. Biol. | pmid:15634841 |
Rogel A et al. | Phospholipase C is involved in the adenosine-activated signal transduction pathway conferring protection against iodoacetic acid-induced injury in primary rat neuronal cultures. | 2005 | Neurosci. Lett. | pmid:15619546 |
Palacios MC et al. | Characterization of an acid phosphatase from Lactobacillus pentosus: regulation and biochemical properties. | 2005 | J. Appl. Microbiol. | pmid:15610436 |
Bobilya DJ et al. | Zinc transport into endothelial cells is a facilitated process. | 1992 | J. Cell. Physiol. | pmid:1560036 |
Meng TC et al. | Development of a modified in-gel assay to identify protein tyrosine phosphatases that are oxidized and inactivated in vivo. | 2005 | Methods | pmid:15588983 |
pmid:15581366 | ||||
pmid:15568816 | ||||
pmid:15554709 | ||||
pmid:15534395 | ||||
Silberberg SD and van Breemen C | A potassium current activated by lemakalim and metabolic inhibition in rabbit mesenteric artery. | 1992 | Pflugers Arch. | pmid:1553259 |
Chung TH et al. | 17beta-estradiol reduces the effect of metabolic inhibition on gap junction intercellular communication in rat cardiomyocytes via the estrogen receptor. | 2004 | J. Mol. Cell. Cardiol. | pmid:15522278 |
Hondorp ER and Matthews RG | Oxidative stress inactivates cobalamin-independent methionine synthase (MetE) in Escherichia coli. | 2004 | PLoS Biol. | pmid:15502870 |
pmid:15494188 | ||||
Adachi T et al. | S-Glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxide. | 2004 | Nat. Med. | pmid:15489859 |
pmid:15488329 | ||||
Renner R | More chloramine complications. | 2004 | Environ. Sci. Technol. | pmid:15487772 |
Chung Y and Cho H | Preparation of highly water soluble tacrolimus derivatives: poly(ethylene glycol) esters as potential prodrugs. | 2004 | Arch. Pharm. Res. | pmid:15460452 |
HOMBURGER F and PFEIFFER PH | Evaluation of diagnostic tests for cancer; inhibition of thermal coagulation of serum by iodoacetic acid, the Huggins-Miller-Jensen test. | 1950 | Cancer | pmid:15405677 |
pmid:15364283 | ||||
Yang Y and Balcarcel RR | 96-well plate assay for sublethal metabolic activity. | 2004 | Assay Drug Dev Technol | pmid:15357916 |
Foucher B et al. | [Stability of blood glucose collected with or without antiglycolytic agent]. | 2004 Sep-Oct | Ann. Biol. Clin. (Paris) | pmid:15355815 |
Song J et al. | Isolation and characterization of an IAA-responsive gene from Gossypium barbadense L. | 2004 | DNA Seq. | pmid:15354358 |
Janusz MJ et al. | Detection of aggrecanase- and MMP-generated catabolic neoepitopes in the rat iodoacetate model of cartilage degeneration. | 2004 | Osteoarthr. Cartil. | pmid:15325638 |
Kuzminskaya EV et al. | Rabbit muscle D-glyceraldehyde-3-phosphate dehydrogenase: half-of-the-sites reactivity of the enzyme modified at arginine residues. | 1992 | Biochem. Biophys. Res. Commun. | pmid:1530616 |
pmid:15299283 | ||||
pmid:15276027 | ||||
pmid:15261284 | ||||
Ogunjimi EO et al. | Evidence for a conformational change in subunit III of bovine heart mitochondrial cytochrome c oxidase. | 2000 | J. Bioenerg. Biomembr. | pmid:15254375 |
pmid:15242734 | ||||
pmid:15234781 | ||||
Cylwik J et al. | The influence of doxycycline on articular cartilage in experimental osteoarthrosis induced by iodoacetate. | 2004 | Folia Morphol. (Warsz) | pmid:15232785 |
Nishida T et al. | Regeneration of defects in articular cartilage in rat knee joints by CCN2 (connective tissue growth factor). | 2004 | J. Bone Miner. Res. | pmid:15231019 |
Hiwatashi K et al. | Purification and characterization of a novel prolyl aminopeptidase from Maitake (Grifola frondosa). | 2004 | Biosci. Biotechnol. Biochem. | pmid:15215614 |
pmid:15209520 | ||||
Furukawa N et al. | [A biochemical study of an animal model with defective muscle glycolysis, induced by iodoacetate administration]. | 1992 | No To Hattatsu | pmid:1520510 |
Adinarayana K et al. | Purification and partial characterization of thermostable serine alkaline protease from a newly isolated Bacillus subtilis PE-11. | 2003 | AAPS PharmSciTech | pmid:15198551 |
Whitton C | Chemical arthrodesis of the distal tarsal joints using sodium monoiodoacetate in 104 horses. | 2004 | Aust. Vet. J. | pmid:15181929 |
Lima-Catelani AR et al. | Variation of genetic expression during development, revealed by esterase patterns in Aedes aegypti (Diptera, Culicidae). | 2004 | Biochem. Genet. | pmid:15168721 |
pmid:15139749 | ||||
Andersen BJ and Marmarou A | Functional compartmentalization of energy production in neural tissue. | 1992 | Brain Res. | pmid:1511302 |
pmid:15088956 | ||||
Pyza E and Górska-Andrzejak J | Involvement of glial cells in rhythmic size changes in neurons of the housefly's visual system. | 2004 | J. Neurobiol. | pmid:15085538 |
Beauvieux MC et al. | Some processes of energy saving and expenditure occurring during ethanol perfusion in the isolated liver of fed rats; a Nuclear Magnetic Resonance study. | 2004 | BMC Physiol. | pmid:15053831 |
Yang L et al. | Purification and characterization of an isoflavone-conjugates-hydrolyzing beta-glucosidase from endophytic bacterium. | 2004 | J. Agric. Food Chem. | pmid:15053533 |
pmid:15052470 | ||||
Dumond H et al. | Site specific changes in gene expression and cartilage metabolism during early experimental osteoarthritis. | 2004 | Osteoarthr. Cartil. | pmid:15023380 |
Rainbow RD et al. | SUR2A C-terminal fragments reduce KATP currents and ischaemic tolerance of rat cardiac myocytes. | 2004 | J. Physiol. (Lond.) | pmid:15020694 |
pmid:15019298 | ||||
Parkinson FE and Xiong W | Stimulus- and cell-type-specific release of purines in cultured rat forebrain astrocytes and neurons. | 2004 | J. Neurochem. | pmid:15009686 |
pmid:14984289 | ||||
Gustafson SB et al. | Evaluation of intra-articularly administered sodium monoiodoacetate-induced chemical injury to articular cartilage of horses. | 1992 | Am. J. Vet. Res. | pmid:1497191 |
pmid:14962487 | ||||
Kamendulis LM and Corcoran GB | Independence and additivity of cultured hepatocyte killing by Ca2+ overload and ATP depletion. | 1992 | Toxicol. Lett. | pmid:1488777 |
ISSEKUTZ B et al. | Tissue metabolism and peripheral circulation. II. Effect of iodoacetic acid on peripheral circulation. | 1951 | Arch Int Physiol | pmid:14857871 |
ISSEKUTZ B et al. | Tissue metabolism and peripheral circulation. I. Effect of iodoacetic acid on the metabolism of muscles "in vivo". | 1951 | Arch Int Physiol | pmid:14857870 |
KOHLER V and BAUER R | [Reticulocytosis of the circulating blood provoked by monoiodoacetic acid as a symptom of the adaptation syndrome]. | 1951 | Arztl Wochensch | pmid:14856887 |
NOELL WK | The effect of iodoacetate on the vertebrate retina. | 1951 | J. Cell. Physiol. | pmid:14832350 |
KOHLER V and SCHARF J | [Importance of metabolic processes sensitive to mono-iodoacetic acid for tissue inflammation]. | 1951 | Klin. Wochenschr. | pmid:14825752 |
LUNDQVIST C | The toxicity of iodoacetic acid and its quantitative relations to inhibition of glycolysis and dental caries. | 1951 | J. Dent. Res. | pmid:14824349 |
GLASS GB et al. | Thermal coagulation point and iodoacetate index as detectors of abnormal serum proteins and underlying illness. | 1951 | Proc. Soc. Exp. Biol. Med. | pmid:14816377 |
SCOTT GT and HAYWARD HR | The influence of the glycolytic inhibitor iodoacetic acid on aging and on the potassium and sodium content of the egg cells of Mactra solidissima. | 1950 | Biol. Bull. | pmid:14791537 |
SANDOW A and KARCZMAR AG | Effect of iodoacetate on changes in muscular latency induced by activity. | 1950 | Am. J. Physiol. | pmid:14789991 |
JACKSON H | Thermal coagulability of serum proteins and the diagnosis of malignant disease. | 1950 | Br Med J | pmid:14777910 |
Chang TK and Cheng JT | Inhibitory effect of xylamine on the uptake of [3H]norepinephrine into primary astrocyte cultures. | 1992 | Brain Res. | pmid:1477731 |
Persson C et al. | Preferential oxidation of the second phosphatase domain of receptor-like PTP-alpha revealed by an antibody against oxidized protein tyrosine phosphatases. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:14762163 |
Sokolov NN and Nikolaev AIa | [Sulfhydryl groups of L-asparaginase A from Pseudomonas fluorescens AG]. | 1976 | Biokhimiia | pmid:14736 |
pmid:14730418 | ||||
Hoskins IA et al. | Use of esterase inhibitors and zone electrophoresis to define bacterial esterases in amniotic fluid. | 1992 | Am. J. Obstet. Gynecol. | pmid:1471669 |
pmid:14705800 | ||||
pmid:14705797 | ||||
pmid:14686916 | ||||
Ohnoki S et al. | Glutamine active site of formylglycinamide ribonucleotide amidotransferase. 1. Labeling of the enzyme with iodoacetate. | 1977 | Biochemistry | pmid:14669 |
Yep A et al. | Identification and characterization of a critical region in the glycogen synthase from Escherichia coli. | 2004 | J. Biol. Chem. | pmid:14665620 |
Dong L and Xu CW | Carbohydrates induce mono-ubiquitination of H2B in yeast. | 2004 | J. Biol. Chem. | pmid:14660635 |
pmid:14642648 | ||||
pmid:14623125 | ||||
Imberti R et al. | Synergism of cyclosporin A and phospholipase inhibitors in protection against lethal injury to rat hepatocytes from oxidant chemicals. | 1992 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:1462047 |