Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Fadda S et al. | Preliminary characterization of beta-decarboxylase activities in Staphylococcus carnosus 833, a strain used in sausage fermentation. | 2003 | FEMS Microbiol. Lett. | pmid:14612250 |
Zhang Q et al. | Purification and characterization of a novel carbaryl hydrolase from Aspergillus niger PY168. | 2003 | FEMS Microbiol. Lett. | pmid:14612234 |
Bove SE et al. | Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetate-induced osteoarthritis. | 2003 | Osteoarthr. Cartil. | pmid:14609535 |
pmid:14607490 | ||||
pmid:14585729 | ||||
Figueirêdo PM et al. | Thiol-independent activity of a cholesterol-binding enterohemolysin produced by enteropathogenic Escherichia coli. | 2003 | Braz. J. Med. Biol. Res. | pmid:14576905 |
Jha S et al. | Covalent modification of cysteine 193 impairs ATPase function of nucleotide-binding domain of a Candida drug efflux pump. | 2003 | Biochem. Biophys. Res. Commun. | pmid:14550284 |
pmid:14518963 | ||||
Bickler PE and Kelleher JA | Fructose-1,6-bisphosphate stabilizes brain intracellular calcium during hypoxia in rats. | 1992 | Stroke | pmid:1440710 |
pmid:14361738 | ||||
Sogawa K and Takahashi K | A novel neutral protease(s) from monkey liver. | 1976 | J. Biochem. | pmid:14127 |
Takahashi K | The structure and function of ribonuclease T1. XXI. Modification of histidine residues in ribonuclease T1 with iodoacetamide. | 1976 | J. Biochem. | pmid:14120 |
Oshima H and Takahashi K | The structure and function of ribonuclease T1. XX. Specific inactivation of ribonuclease T1 by reaction with tosylglycolate. | 1976 | J. Biochem. | pmid:14119 |
pmid:14089454 | ||||
Plishker GA et al. | Calcium-activated potassium transport and high molecular weight forms of calpromotin. | 1992 | J. Biol. Chem. | pmid:1400494 |
Adams EM et al. | Lack of [3H]quinuclidinyl benzylate binding to biologically relevant binding sites on mononuclear cells. | 1992 | Brain Behav. Immun. | pmid:1392105 |
Cummings JG et al. | Reductive half-reaction in medium-chain acyl-CoA dehydrogenase: modulation of internal equilibrium by carboxymethylation of a specific methionine residue. | 1992 | Biochemistry | pmid:1390638 |
Dunham J et al. | Structural and metabolic changes in articular cartilage induced by iodoacetate. | 1992 | Int J Exp Pathol | pmid:1390193 |
Lin YJ et al. | Disulfide-linked and noncovalent dimers of p185HER-2 in human breast carcinoma cells. | 1992 | J. Cell. Biochem. | pmid:1379605 |
pmid:13775552 | ||||
Guiraud P et al. | Cultured human skin fibroblasts absorb 65Zn. Optimization of the method and study of the mechanisms involved. | 1992 Jan-Mar | Biol Trace Elem Res | pmid:1375058 |
pmid:13681437 | ||||
Kempski O et al. | Swelling of C6 glioma cells and astrocytes from glutamate, high K+ concentrations or acidosis. | 1992 | Prog. Brain Res. | pmid:1363149 |
Greenhalgh DA et al. | Effect of introducing different carboxylate-containing side chains at position 85 on chromophore formation and proton transport in bacteriorhodopsin. | 1992 | J. Biol. Chem. | pmid:1361187 |
Zeevalk GD and Nicklas WJ | NMDA receptors, cellular edema, and metabolic stress. | 1992 | Ann. N. Y. Acad. Sci. | pmid:1353336 |
pmid:13448863 | ||||
pmid:13402898 | ||||
MejÃa-Alvarez R and Marban E | Mechanism of the increase in intracellular sodium during metabolic inhibition: direct evidence against mediation by voltage-dependent sodium channels. | 1992 | J. Mol. Cell. Cardiol. | pmid:1336064 |
Siksnys V and Pleckaityte M | Role of the reactive cysteine residue in restriction endonuclease Cfr9I. | 1992 | Biochim. Biophys. Acta | pmid:1332782 |
Milne KG et al. | Inhibition of the GlcNAc transferase of the glycosylphosphatidylinositol anchor biosynthesis in African trypanosomes. | 1992 | Eur. J. Biochem. | pmid:1325903 |
pmid:13248903 | ||||
Knowles MR et al. | Bovine inositol monophosphatase. Modification, identification and mutagenesis of reactive cysteine residues. | 1992 | Biochem. J. | pmid:1322134 |
Rae AS and Strickland KP | Studies on phosphate transport in Escherichia coli. II. Effects of metabolic inhibitors and divalent cations. | 1976 | Biochim. Biophys. Acta | pmid:132192 |
Stinson MW et al. | Inhibition of Porphyromonas gingivalis adhesion to Streptococcus gordonii by human submandibular-sublingual saliva. | 1992 | Infect. Immun. | pmid:1319402 |
Xia Y et al. | Oxidative and glycolytic pathways in rat (newborn and adult) and turtle brain: role during anoxia. | 1992 | Am. J. Physiol. | pmid:1314516 |
Hruz PW and Miziorko HM | Avian 3-hydroxy-3-methylglutaryl-CoA lyase: sensitivity of enzyme activity to thiol/disulfide exchange and identification of proximal reactive cysteines. | 1992 | Protein Sci. | pmid:1304393 |
EBE M | Effect of glutamic acid, NaCN and monoiodoacetic acid on the potential changes of isolated toad's brain. | 1952 | Tohoku J. Exp. Med. | pmid:13005477 |
Rosenthal M and Sick TJ | Glycolytic and oxidative metabolic contributions to potassium ion transport in rat cerebral cortex. | 1992 | Can. J. Physiol. Pharmacol. | pmid:1295667 |
pmid:12952458 | ||||
Tůmová L et al. | [Iodoacetic acid as a potential elicitor of increased production of flavonoids in a culture of Ononis arvensis L. in vitro]. | 2003 | Ceska Slov Farm | pmid:12924071 |
Vera PL and Meyer-Siegler KL | Anatomical location of macrophage migration inhibitory factor in urogenital tissues, peripheral ganglia and lumbosacral spinal cord of the rat. | 2003 | BMC Neurosci | pmid:12908877 |
Chen X et al. | [Detection of proteolytic activity of hepatitis C virus NS3-4A protease using enzymelinked immunosorbent assay]. | 2000 | Zhongguo Yi Xue Ke Xue Yuan Xue Bao | pmid:12903484 |
Bürkert E et al. | The C2-like beta-barrel domain mediates the Ca2+-dependent resistance of 5-lipoxygenase activity against inhibition by glutathione peroxidase-1. | 2003 | J. Biol. Chem. | pmid:12893830 |
pmid:12892929 | ||||
Massieu L et al. | Acetoacetate protects hippocampal neurons against glutamate-mediated neuronal damage during glycolysis inhibition. | 2003 | Neuroscience | pmid:12890508 |
pmid:12882641 | ||||
Ding PZ | An investigation of cysteine mutants on the cytoplasmic loop X/XI in the melibiose transporter of Escherichia coli by using thiol reagents: implication of structural conservation of charged residues. | 2003 | Biochem. Biophys. Res. Commun. | pmid:12878191 |
Kim YJ | Partial inhibition of biohydrogenation of linoleic acid can increase the conjugated linoleic acid production of Butyrivibrio fibrisolvens A38. | 2003 | J. Agric. Food Chem. | pmid:12848494 |
Flanagan PR and Zbarsky SH | Rat intestinal phosphodiesterase II. Properties of the highly purified enzyme and its inactivation by iodoacetic acid. | 1977 | Biochim. Biophys. Acta | pmid:12824 |
Maekawa Y et al. | A tetrazolium-based colorimetric assay for metabolic activity of stored blood platelets. | 2003 | Thromb. Res. | pmid:12818255 |
Lucas J et al. | Susceptibility of myelin proteins to a neutral endoproteinase: the degradation of myelin basic protein (MBP) and P2 protein by purified bovine brain multicatalytic proteinase complex (MPC). | 1992 | Neurochem. Res. | pmid:1281293 |
Bárány M et al. | Structural changes in myosin during contraction and the state of ATP in the intact frog muscle. | 1975 | J. Supramol. Struct. | pmid:127883 |
pmid:12787820 | ||||
Zolotova VF et al. | [Sodium release from tissue paracellular space under the influence of angiotensin II]. | 1976 | Fiziol Zh SSSR Im I M Sechenova | pmid:1278538 |
Buckel W | Acetic anhydride: an intermediate analogue in the acyl-exchange reaction of citramalate lyase. | 1976 | Eur. J. Biochem. | pmid:1278157 |
Hallak GJ and Wilkinson JH | Membrane permeability in normal human lymphocytes and lymphocytes from patients with chronic lymphatic leukaemia. | 1976 | Clin. Chim. Acta | pmid:1277564 |
pmid:12770769 | ||||
Dayton WR et al. | A Ca2+-activated protease possibly involved in myofibrillar protein turnover. Partial characterization of the purified enzyme. | 1976 | Biochemistry | pmid:1276131 |
pmid:12760417 | ||||
Mori M | A study on the nuclear extrusion of mammalian erythroblast. | 1975 | Acta Med. Okayama | pmid:127510 |
Winkler BS et al. | Modulation of the Pasteur effect in retinal cells: implications for understanding compensatory metabolic mechanisms. | 2003 | Exp. Eye Res. | pmid:12742354 |
Wentzel P et al. | Maternal diabetes in vivo and high glucose in vitro diminish GAPDH activity in rat embryos. | 2003 | Diabetes | pmid:12716756 |
Harrison GJ et al. | Glycolytic buffering affects cardiac bioenergetic signaling and contractile reserve similar to creatine kinase. | 2003 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12714331 |
Jensen JB and Edgar SA | Effects of antiphagocytic agents on penetration of Eimeria magna sporozoites into cultured cells. | 1976 | J. Parasitol. | pmid:1263027 |
Ito K et al. | Novel aminopeptidase specific for glycine from Actinomucor elegans. | 2003 | Biosci. Biotechnol. Biochem. | pmid:12619677 |
Battista N et al. | Anandamide uptake by synaptosomes from human, mouse and rat brain: inhibition by glutamine and glutamate. | 2002 | Lipids Health Dis | pmid:12617751 |
Scarpace PJ and Neuman WF | The blood: bone disequilibrium. II. Evidence against the active accumulation of calcium or phosphate into the bone extracellular fluid. | 1976 | Calcif Tissue Res | pmid:1260485 |
Scarpace PJ and Neuman WF | The blood: bone disequilibrium. I. The active accumulation of K+ into the bone extracellular fluid. | 1976 | Calcif Tissue Res | pmid:1260484 |
Gupta SR et al. | Effect of some inhibitors on aflatoxin-production in a synthetic medium and on the incorporation of acetate-1- 14C into aflatoxins by resting mycelia of Aspergillus parasiticus. | 1976 | Bull Environ Contam Toxicol | pmid:1260151 |
Newcomb LL et al. | Glucose regulation of Saccharomyces cerevisiae cell cycle genes. | 2003 | Eukaryotic Cell | pmid:12582131 |
pmid:12565709 | ||||
Phillips ER and Perdue JF | The expression and localization of surface neoantigens in transformed and untransformed cultured cells infected with avian tumor viruses. | 1976 | J. Supramol. Struct. | pmid:1256061 |
pmid:12559101 | ||||
Di-Capua N et al. | Protein kinase C-epsilon is involved in the adenosine-activated signal transduction pathway conferring protection against ischemia-reperfusion injury in primary rat neuronal cultures. | 2003 | J. Neurochem. | pmid:12559003 |
Damon BM et al. | The carnosine C-2 proton's chemical shift reports intracellular pH in oxidative and glycolytic muscle fibers. | 2003 | Magn Reson Med | pmid:12541242 |
Müller M and Ballanyi K | Dynamic recording of cell death in the in vitro dorsal vagal nucleus of rats in response to metabolic arrest. | 2003 | J. Neurophysiol. | pmid:12522201 |
Kito Y and Suzuki H | Pacemaker frequency is increased by sodium nitroprusside in the guinea pig gastric antrum. | 2003 | J. Physiol. (Lond.) | pmid:12509488 |
Espelt MV et al. | Volumetric and ionic responses of goldfish hepatocytes to anisotonic exposure and energetic limitation. | 2003 | J. Exp. Biol. | pmid:12502772 |
Ikemoto A et al. | Glycolysis and glutamate accumulation into synaptic vesicles. Role of glyceraldehyde phosphate dehydrogenase and 3-phosphoglycerate kinase. | 2003 | J. Biol. Chem. | pmid:12488440 |
Ghelis C et al. | The conformational oscillation of delta-chymotrypsin involvement of methionine-192. | 1975 | Eur. J. Biochem. | pmid:1247 |
Kuo SC and Lampen JO | Action of cytochalasin A, a sulfhydryl-reactive agent, on sugar metabolism and membrane-bound adenosine triphosphatase of yeast. | 1975 | Biochim. Biophys. Acta | pmid:124588 |
Luchnik NV | [Phenomenon of pseudomutagenesis: experiments with modifiers of cell metabolism in human lymphocytes]. | 2002 | Genetika | pmid:12449644 |
Fonda ML | Bromopyruvate inactivation of glutamate apodecarboxylase. Kinetics and specificity. | 1976 | J. Biol. Chem. | pmid:1244350 |
pmid:12435144 | ||||
Peral MJ et al. | Human, rat and chicken small intestinal Na+ - Cl- -creatine transporter: functional, molecular characterization and localization. | 2002 | J. Physiol. (Lond.) | pmid:12433955 |
pmid:12384169 | ||||
Parkinson AJ and Kalmakoff J | Tritium labeling of immunoglobulin with iodoacetic acid. | 1975 Jun-Jul | Int J Appl Radiat Isot | pmid:1237470 |
Zeppezauer E et al. | Carboxymethylation of horse-liver alcohol dehydrogenase in the crystalline state. The active-site zinc region and general anion-binding site of the enzyme correlated in primary and teritiary structures. | 1975 | Eur. J. Biochem. | pmid:1237402 |
Jung J et al. | Interaction of cofilin with triose-phosphate isomerase contributes glycolytic fuel for Na,K-ATPase via Rho-mediated signaling pathway. | 2002 | J. Biol. Chem. | pmid:12359716 |
pmid:12297233 | ||||
Knock FE et al. | Effects of selected sulfhydryl inhibitors on nonhistone chromosomal proteins of HeLa cells. | 1975 | Oncology | pmid:1228540 |
pmid:12227811 | ||||
pmid:12210119 | ||||
Takesada H et al. | Hydrogen-deuterium exchange in the histidine residues of bovine alpha-lactalbumin. | 1976 | J. Biochem. | pmid:12155 |
Yang NC et al. | ATP depletion is an important factor in DHEA-induced growth inhibition and apoptosis in BV-2 cells. | 2002 | Life Sci. | pmid:12148690 |
Kutchai H | Uptake of sorbitol by chick embryo heart cells at various stages of development. | 1975 | J. Membr. Biol. | pmid:1214274 |
pmid:12125098 | ||||
Moreira CR et al. | Identification of prolylcarboxypeptidase as the cell matrix-associated prekallikrein activator. | 2002 | FEBS Lett. | pmid:12123826 |
pmid:12106909 | ||||
pmid:12101291 |