Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Osteoarthritis, Spine D055013 2 associated lipids
Osteophyte D054850 2 associated lipids
Monckeberg Medial Calcific Sclerosis D050380 1 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Stroke D020521 32 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Thrombophilia D019851 6 associated lipids
Arthralgia D018771 8 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Reperfusion Injury D015427 65 associated lipids
Wounds and Injuries D014947 20 associated lipids
Vitamin D Deficiency D014808 13 associated lipids
Vascular Diseases D014652 16 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Thrombocytopenia D013921 15 associated lipids
Theileriasis D013801 7 associated lipids
Temporomandibular Joint Disorders D013705 4 associated lipids
Starvation D013217 47 associated lipids
Sarcoma 180 D012510 21 associated lipids
Rigor Mortis D012298 1 associated lipids
Rickets D012279 6 associated lipids
Retinitis D012173 4 associated lipids
Cumulative Trauma Disorders D012090 2 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Pain D010146 64 associated lipids
Osteoarthritis D010003 4 associated lipids
Nerve Degeneration D009410 53 associated lipids
Muscle Cramp D009120 3 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Lymphoma D008223 18 associated lipids
Lung Neoplasms D008175 171 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Inflammation D007249 119 associated lipids
Hypocalcemia D006996 12 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hyperalgesia D006930 42 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
Glycogen Storage Disease D006008 4 associated lipids
Glioma D005910 112 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Epilepsy D004827 35 associated lipids
Coronary Disease D003327 70 associated lipids
Clonorchiasis D003003 1 associated lipids
Brain Ischemia D002545 89 associated lipids
Byssinosis D002095 11 associated lipids
Burns D002056 34 associated lipids
Brain Edema D001929 20 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
Blindness D001766 6 associated lipids
Arthritis, Experimental D001169 24 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Yang R et al. Partial purification and characterisation of cysteine protease in wheat germ. 2011 J. Sci. Food Agric. pmid:21702054
Orita S et al. Pain-related sensory innervation in monoiodoacetate-induced osteoarthritis in rat knees that gradually develops neuronal injury in addition to inflammatory pain. 2011 BMC Musculoskelet Disord pmid:21679434
Nam J et al. Transcriptome-wide gene regulation by gentle treadmill walking during the progression of monoiodoacetate-induced arthritis. 2011 Arthritis Rheum. pmid:21400474
Siebelt M et al. Quantifying osteoarthritic cartilage changes accurately using in vivo microCT arthrography in three etiologically distinct rat models. 2011 J. Orthop. Res. pmid:21520262
Huang J et al. Isolation, characterization and identification of a Paracoccus sp. 2-haloacid-degrading bacterium from the marine sponge Hymeniacidon perlevis. 2011 J. Basic Microbiol. pmid:21298680
Ataman OV and Ataman IuO [Comparative characteristic of energy supply disturbances in arterial and venous walls of rabbits with alloxan diabetes and monoiodacetate intoxication]. 2011 Fiziol Zh pmid:21848224
Wang W et al. Selective rod degeneration and partial cone inactivation characterize an iodoacetic acid model of Swine retinal degeneration. 2011 Invest. Ophthalmol. Vis. Sci. pmid:21896868
Nam J et al. Sequential alterations in catabolic and anabolic gene expression parallel pathological changes during progression of monoiodoacetate-induced arthritis. 2011 PLoS ONE pmid:21931681
Buchwalow I et al. Non-specific binding of antibodies in immunohistochemistry: fallacies and facts. 2011 Sci Rep pmid:22355547
Hettling H and van Beek JH Analyzing the functional properties of the creatine kinase system with multiscale 'sloppy' modeling. 2011 PLoS Comput. Biol. pmid:21912519
Bezawada J et al. Recovery of Bacillus licheniformis Alkaline Protease from Supernatant of Fermented Wastewater Sludge Using Ultrafiltration and Its Characterization. 2011 Biotechnol Res Int pmid:21876816
Cherel P et al. Joint analysis of quantitative trait loci and major-effect causative mutations affecting meat quality and carcass composition traits in pigs. 2011 BMC Genet. pmid:21875434
Rawlings ND et al. Asparagine peptide lyases: a seventh catalytic type of proteolytic enzymes. 2011 J. Biol. Chem. pmid:21832066
House SA et al. Giardia flagellar motility is not directly required to maintain attachment to surfaces. 2011 PLoS Pathog. pmid:21829364
Kovacic PB et al. New insights into cytosolic glucose levels during differentiation of 3T3-L1 fibroblasts into adipocytes. 2011 J. Biol. Chem. pmid:21349852
Ulanovskaya OA et al. A pairwise chemical genetic screen identifies new inhibitors of glucose transport. 2011 Chem. Biol. pmid:21338919
Liao HH et al. Down-regulation of granulocyte-macrophage colony-stimulating factor by 3C-like proteinase in transfected A549 human lung carcinoma cells. 2011 BMC Immunol. pmid:21324206
Porteus C et al. Time domains of the hypoxic ventilatory response in ectothermic vertebrates. 2011 J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. pmid:21312038
Sánchez-Aragó M and Cuezva JM The bioenergetic signature of isogenic colon cancer cells predicts the cell death response to treatment with 3-bromopyruvate, iodoacetate or 5-fluorouracil. 2011 J Transl Med pmid:21303518
Samgina TY et al. Novel cysteine tags for the sequencing of non-tryptic disulfide peptides of anurans: ESI-MS study of fragmentation efficiency. 2011 J. Am. Soc. Mass Spectrom. pmid:21979873