Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Pain D010146 64 associated lipids
Lung Neoplasms D008175 171 associated lipids
Wounds and Injuries D014947 20 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Sarcoma 180 D012510 21 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Osteoarthritis D010003 4 associated lipids
Coronary Disease D003327 70 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Glioma D005910 112 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Lymphoma D008223 18 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Brain Edema D001929 20 associated lipids
Stroke D020521 32 associated lipids
Starvation D013217 47 associated lipids
Hypocalcemia D006996 12 associated lipids
Brain Ischemia D002545 89 associated lipids
Epilepsy D004827 35 associated lipids
Nerve Degeneration D009410 53 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Hyperalgesia D006930 42 associated lipids
Thrombocytopenia D013921 15 associated lipids
Hyperlipidemias D006949 73 associated lipids
Rickets D012279 6 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
Byssinosis D002095 11 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Vitamin D Deficiency D014808 13 associated lipids
Vascular Diseases D014652 16 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Blindness D001766 6 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Temporomandibular Joint Disorders D013705 4 associated lipids
Arthralgia D018771 8 associated lipids
Osteophyte D054850 2 associated lipids
Glycogen Storage Disease D006008 4 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Retinitis D012173 4 associated lipids
Theileriasis D013801 7 associated lipids
Muscle Cramp D009120 3 associated lipids
Rigor Mortis D012298 1 associated lipids
Thrombophilia D019851 6 associated lipids
Cumulative Trauma Disorders D012090 2 associated lipids
Monckeberg Medial Calcific Sclerosis D050380 1 associated lipids
Clonorchiasis D003003 1 associated lipids
Osteoarthritis, Spine D055013 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

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Authors Title Published Journal PubMed Link
Cheng KW Carboxymethylation of methionine residues in bovine pituitary luteinizing hormone and its subunits. Location of specifically modified methionine residues. 1976 Biochem. J. pmid:999646
Santos MS et al. Stimulation of immunoreactive insulin release by glucose in rat brain synaptosomes. 1999 Neurochem. Res. pmid:9973234
Schneider WJ and Roehr M Purification and properties of penicillin acylase of Bovista plumbea. 1976 Biochim. Biophys. Acta pmid:990310
Karduck A et al. Morphological and physiological findings on hair cells with impaired metabolism (nitrogen, monoiodoacetate) in Caiman crocodilus with reference to sudden deafness. 1976 Arch Otorhinolaryngol pmid:989728
Lundell N and Schreitmüller T Sample preparation for peptide mapping--A pharmaceutical quality-control perspective. 1999 Anal. Biochem. pmid:9887211
Prakash O and Bhushan G A study of inhibition of urease from seeds of the water melon (Citrullus vulgaris). 1998 J. Enzym. Inhib. pmid:9879515
Takenaka F and Watanabe A Effects of iodoacetate and anoxia on phosphate metabolism in isolated perfused rat hearts. 1976 Arch Int Pharmacodyn Ther pmid:984971
Stopp M et al. Different inhibitory effects of 2,4-dinitrophenol, iodoacetate, and probenecid on renal excretion of p-aminohippurate, cyclopenthiazide, and sulfamethoxypyridazine in rats. 1976 Acta Biol. Med. Ger. pmid:983625
Chanda PK and Chatterjee SN Molecular weight analysis of the polypeptides of cholera phage PL 163/10 by polyacrylamide gel electrophoresis. 1976 Acta Virol. pmid:9816
Mastrogiacomo A et al. Intrinsic membrane association of Drosophila cysteine string proteins. 1998 FEBS Lett. pmid:9771899
Corfield AP et al. The metabolism of O-acyl-N-acylneuraminic acids. Biosynthesis of O-acylated sialic acids in bovine and equine submandibular glands. 1976 Eur. J. Biochem. pmid:976276
Quick M and Jung H A conserved aspartate residue, Asp187, is important for Na+-dependent proline binding and transport by the Na+/proline transporter of Escherichia coli. 1998 Biochemistry pmid:9753469
Schumacher CA et al. Energy-dependent transport of calcium to the extracellular space during acute ischemia of the rat heart. 1998 J. Mol. Cell. Cardiol. pmid:9737948
Shin HH and Choi HS Purification and characterization of cysteine protease from Pleurotus ostreatus. 1998 Biosci. Biotechnol. Biochem. pmid:9720226
Callahan JW and Gerrie J GM1-ganglioside and lactosylceramide beta-galactosidase from rabbit brain: inhibitor and substrate competition studies. 1976 Can. J. Biochem. pmid:971464
Laakso ML and Oja SS Factors influencing the insulin space in cerebral cortex slices from adult and 7-day-old rats. 1976 Acta Physiol. Scand. pmid:970146
Gilmour KM et al. Transepithelial potential of cultured branchial epithelia from rainbow trout under symmetrical conditions. 1998 In Vitro Cell. Dev. Biol. Anim. pmid:9661043
Hilliard CA et al. Chromosome aberrations in vitro related to cytotoxicity of nonmutagenic chemicals and metabolic poisons. 1998 Environ. Mol. Mutagen. pmid:9654240
Kurokawa T et al. Purification and characterization of a lectin from Wistaria floribunda seeds. 1976 J. Biol. Chem. pmid:965385
Lancaster MK and Harrison SM Changes in contraction, cytosolic Ca2+ and pH during metabolic inhibition and upon restoration of mitochondrial respiration in rat ventricular myocytes. 1998 Exp. Physiol. pmid:9639344
Bakken IJ et al. [U-13C] aspartate metabolism in cultured cortical astrocytes and cerebellar granule neurons studied by NMR spectroscopy. 1998 Glia pmid:9633811
Holdobina OV [Changes in the total calcium content and in the activity of alkaline phosphatase and gamma-glutamyltransferase in the blood serum of rats with Mönckeberg's experimental arteriosclerosis]. 1998 Fiziol Zh pmid:9619411
Jensen PK et al. Monitoring protein refolding induced by disulfide formation using capillary isoelectric focusing-electrospray ionization mass spectrometry. 1998 Anal. Chem. pmid:9608843
Bell SD et al. RNA molecules that bind to and inhibit the active site of a tyrosine phosphatase. 1998 J. Biol. Chem. pmid:9603938
Schwarzbaum PJ et al. Functional role of ecto-ATPase activity in goldfish hepatocytes. 1998 Am. J. Physiol. pmid:9575966
Dizon J et al. Metabolic inhibition in the perfused rat heart: evidence for glycolytic requirement for normal sodium homeostasis. 1998 Am. J. Physiol. pmid:9575910
Salter DW and Cook JS Reversible independent alterations in glucose transport and metabolism in cultured human cells deprived of glucose. 1976 J. Cell. Physiol. pmid:956278
Plagemann PG et al. Transport and countertransport of thymidine in ATP depleted and thymidine kinase-deficient Novikoff rat hepatoma and mouse L cells: evidence of a high Km facilitated diffusion system with wide nucleoside specificity. 1976 J. Cell. Physiol. pmid:956273
Hacker TA et al. The role of glucose metabolism in a pig heart model of short-term hibernation. 1998 Mol. Cell. Biochem. pmid:9546633
Santos RM et al. Bursting electrical activity generated in the presence of KATP channel blockers. Pharmacology, sensitivity to intracellular pH and modulation by glucose metabolism. 1997 Adv. Exp. Med. Biol. pmid:9544253
Price NC and Hunter MG Non-identical behaviour of the subunits of rabbit muscule creatine kinase. 1976 Biochim. Biophys. Acta pmid:953037
Simonson LG et al. Characterization of an extracellular dextranase from Fusarium moniliforme. 1975 Appl Microbiol pmid:953
Houghten RA and Li CH Studies on pituitary prolactin. 39. Reaction of the ovine hormone with hydrogen peroxide. 1976 Biochim. Biophys. Acta pmid:952954
Bakken IJ et al. [U-13C]glutamate metabolism in astrocytes during hypoglycemia and hypoxia. 1998 J. Neurosci. Res. pmid:9512008
Cooke KR Effect of the CO-2-bicarbonate buffer system on the water and ion contents of rat renal cortical slices. 1976 Biochim. Biophys. Acta pmid:949507
Jakobi H et al. [New animal experiments on aerobic and anareobic inner ear metabolism]. 1976 Jul-Aug Acta Otolaryngol. pmid:948989
Izumi Y et al. beta-Hydroxybutyrate fuels synaptic function during development. Histological and physiological evidence in rat hippocampal slices. 1998 J. Clin. Invest. pmid:9486983
Post JA et al. pHe, [Ca2+]e, and cell death during metabolic inhibition: role of phospholipase A2 and sarcolemmal phospholipids. 1998 Am. J. Physiol. pmid:9458847
Vezzoli A et al. Quantitative analysis of anaerobic metabolism in resting anoxic muscle by 31P and 1H MRS. 1997 Biochim. Biophys. Acta pmid:9452766
Vega MC et al. The three-dimensional structure of Cys-47-modified mouse liver glutathione S-transferase P1-1. Carboxymethylation dramatically decreases the affinity for glutathione and is associated with a loss of electron density in the alphaB-310B region. 1998 J. Biol. Chem. pmid:9446594
Paffenholz V et al. Uptake of partially thiolated DNA by ascites tumor cells. 1976 Cancer Res. pmid:944094
Marrone L and Viswanatha T Effect of selective cysteine --> alanine replacements on the catalytic functions of lysine: N6-hydroxylase. 1997 Biochim. Biophys. Acta pmid:9434117
Sugimoto S et al. [A procedure for electroretinogram (ERG) recording in mice--effect of monoiodoacetic acid on the ERG in pigmented mice]. 1997 J Toxicol Sci pmid:9430091
Ranadive NS et al. Photolysis of mast cells in presence of protoporphyrin. 1979 Acta Derm. Venereol. pmid:94207
Parry S et al. Identification of active-site histidine residues of a self-incompatibility ribonuclease from a wild tomato. 1997 Plant Physiol. pmid:9414554
Nakayama S et al. Consequences of metabolic inhibition in smooth muscle isolated from guinea-pig stomach. 1997 J. Physiol. (Lond.) pmid:9409485
Agalakova NI et al. Differential effects of glycolytic and oxidative metabolism blockers on the Na-K pump in erythrocytes of the frog, Rana temporaria. 1997 J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. pmid:9404018
Chandra A et al. Modification of aldose reductase by S-nitrosoglutathione. 1997 Biochemistry pmid:9398310
Rogers GA et al. Facile alkylation of methionine by benzyl bromide and demonstration of fumarase inactivation accompanied by alkylation of a methionine residue. 1976 J. Biol. Chem. pmid:9397
Izumi Y et al. Endogenous monocarboxylates sustain hippocampal synaptic function and morphological integrity during energy deprivation. 1997 J. Neurosci. pmid:9391000
Huang YC et al. Identification of the subunits and target peptides of pig heart NAD-specific isocitrate dehydrogenase modified by the affinity label 8-(4-bromo-2,3-dioxobutylthio)NAD. 1997 Arch. Biochem. Biophys. pmid:9390193
Kennedy JF and Chaplin MF The structures of the carbohydrate moieties of the alpha subunit of human chorionic gonadotrophin. 1976 Biochem. J. pmid:938481
Wu ML et al. Capacitative Ca2+ influx in glial cells is inhibited by glycolytic inhibitors. 1997 Glia pmid:9383040
Bullock AJ and Wray S The effects of metabolic inhibition on force, Ca2+ and pHi in guinea-pig ureteric smooth muscle. 1998 Pflugers Arch. pmid:9382937
Wendt IR and Gibbs CL Recovery heat production of mammalian fast- and slow-twitch muscles. 1976 Am. J. Physiol. pmid:937562
Wendt IR and Chapman JB Fluorometric studies of recovery metabolism of rat fast- and slow-twitch muscles. 1976 Am. J. Physiol. pmid:937554
Jornot L et al. Modulation of the DNA binding activity of transcription factors CREP, NFkappaB and HSF by H2O2 and TNF alpha. Differences between in vivo and in vitro effects. 1997 FEBS Lett. pmid:9373190
Polliotti BM et al. Culture of first-trimester and full-term human chorionic villus explants: role of human chorionic gonadotropin and human placental lactogen as a viability index. 1995 Early Pregnancy pmid:9363259
Chen CJ et al. Characterization and purification of a lipoxygenase inhibitor in human epidermoid carcinoma A431 cells. 1997 Biochem. J. pmid:9355752
Kim H et al. Evidence for the essential histidine residues in geranylgeranyl transferase type I from bovine testis. 1997 Biochem. Mol. Biol. Int. pmid:9350353
Garnett HM Energy-dependent accumulation of Ca2+ by human embryonic lung fibroblasts. 1979 Arch. Int. Physiol. Biochim. pmid:93434
Clarke KA et al. Gait analysis in a rat model of osteoarthrosis. 1997 Physiol. Behav. pmid:9333186
Ness LS et al. Survival of Escherichia coli cells exposed to iodoacetate and chlorodinitrobenzene is independent of the glutathione-gated K+ efflux systems KefB and KefC. 1997 Appl. Environ. Microbiol. pmid:9327573
Waki A et al. Effects of antitumor agents on 3H-2-deoxyglucose uptake in tumor cells and their relationship with the main targets of the antitumor agents. 1997 Ann Nucl Med pmid:9310165
Santori G et al. Different efficacy of iodoacetic acid and N-ethylmaleimide in high-performance liquid chromatographic measurement of liver glutathione. 1997 J. Chromatogr. B Biomed. Sci. Appl. pmid:9300880
Monika EM et al. A thioreduction pathway tethered to the membrane for periplasmic cytochromes c biogenesis; in vitro and in vivo studies. 1997 J. Mol. Biol. pmid:9299319
Izumi Y et al. Monocarboxylates (pyruvate and lactate) as alternative energy substrates for the induction of long-term potentiation in rat hippocampal slices. 1997 Neurosci. Lett. pmid:9292881
Rego AC et al. Adenosine triphosphate degradation products after oxidative stress and metabolic dysfunction in cultured retinal cells. 1997 J. Neurochem. pmid:9282947
Kuwata K et al. Cross-relaxation times of normal and biochemically induced osteoarthritic rabbit knee cartilages. 1997 Jpn. J. Physiol. pmid:9271160
Ahearn GA and Maginniss LA Kinetics of glucose transport by the perfused mid-gut of the freshwater prawn Macrobrachium rosenberg ii. 1977 J. Physiol. (Lond.) pmid:925985
López de Heredia M et al. The integrity of thiol groups is essential for catalytic efficiency of rat liver cholesterol ester hydrolase either in microsomal membranes or after solubilization. 1996 Enzyme Protein pmid:9252786
Halász P and Polgár L Negatively charged reactants as probes in the study of the essential mercaptide-imidazolium ion-pair of thiolenzymes. 1977 Eur. J. Biochem. pmid:923564
Gramolini A and Renaud JM Blocking ATP-sensitive K+ channel during metabolic inhibition impairs muscle contractility. 1997 Am. J. Physiol. pmid:9227423
Miles PR et al. The effect of inorganic phosphate on sodium fluxes in dog red blood cells. 1977 Biochim. Biophys. Acta pmid:921968
Himmelreich U and Kuchel PW 13C-NMR studies of transmembrane electron transfer to extracellular ferricyanide in human erythrocytes. 1997 Eur. J. Biochem. pmid:9219520
Matthews RT et al. Iodoacetate produces striatal excitotoxic lesions. 1997 J. Neurochem. pmid:9202321
Burton FL and Smith GL The effect of cromakalim on intracellular [Ca2+] in isolated rat skeletal muscle during fatigue and metabolic blockade. 1997 Exp. Physiol. pmid:9179567
Bender AS et al. The rapid L- and D-aspartate uptake in cultured astrocytes. 1997 Neurochem. Res. pmid:9178956
Fang HK et al. Cardiac contractile function during coronary stenosis in dogs: association of adenosine in glycolytic dependence. 1997 Am. J. Physiol. pmid:9176286
D'Onofrio C et al. The influence of some metabolic inhibitors on in vitro phagocytizing macrophages. I. The behaviour of human macrophages. 1977 Med. Microbiol. Immunol. pmid:916975
Rangarajan M et al. Biochemical characterization of the arginine-specific proteases of Porphyromonas gingivalis W50 suggests a common precursor. 1997 Biochem. J. pmid:9169603
Xu W et al. Identification of critical positive charges in XIP, the Na/Ca exchange inhibitory peptide. 1997 Arch. Biochem. Biophys. pmid:9169015
Cappelli-Bigazzi M et al. Role of oxidative metabolism on endothelium-dependent vascular relaxation of isolated vessels. 1997 J. Mol. Cell. Cardiol. pmid:9152848
O'Flaherty JT et al. Influence of inhibitors of cellular function on chemotactic factor-induced neutrophil aggregation. 1977 J. Immunol. pmid:915280
Nasu T and Baba K Mechanics of manganese ions-induced contraction of ileal longitudinal muscle in Ca(2+)-free, high-K+ medium. 1997 Gen. Pharmacol. pmid:9147016
Peretz M et al. Cysteine reactivity in Thermoanaerobacter brockii alcohol dehydrogenase. 1997 Protein Sci. pmid:9144779
Kajikawa H et al. Glucose transport by mixed ruminal bacteria from a cow. 1997 Appl. Environ. Microbiol. pmid:9143117
Xie LH et al. Development of inwardly rectifying K+ channel family in rat ventricular myocytes. 1997 Am. J. Physiol. pmid:9139958
Lorenz JN and Paul RJ Dependence of Ca2+ channel currents on endogenous and exogenous sources of ATP in portal vein smooth muscle. 1997 Am. J. Physiol. pmid:9124463
Pensa B et al. Selective reactivity of rhodanese sulfhydryl groups with 5,5'-dithio-bis(2-nitrobenzoic acid). 1977 Biochim. Biophys. Acta pmid:911854
Carne AF and U S Chemical modification of proteins for sequence analysis. 1997 Methods Mol. Biol. pmid:9116830
Johnson V and Maack T Renal extraction, filtration, absorption, and catabolism of growth hormone. 1977 Am. J. Physiol. pmid:910912
Ginsberg MH et al. Release of platelet constituents by monosodium urate crystals. 1977 J. Clin. Invest. pmid:908764
Houghten RA and Li CH Reaction of human choriomammotropin with hydrogen peroxide. 1977 Eur. J. Biochem. pmid:908331
Oda Y et al. Purification and properties of poly(3-hydroxybutyrate) depolymerase from the fungus Paecilomyces lilacinus D218. 1997 Curr. Microbiol. pmid:9058543
Gali RR and Board PG Identification of an essential cysteine residue in human glutathione synthase. 1997 Biochem. J. pmid:9003420
Loeuille D et al. In vitro magnetic resonance microimaging of experimental osteoarthritis in the rat knee joint. 1997 J. Rheumatol. pmid:9002024
Reshef A et al. Preconditioning of primary rat neuronal cultures against ischemic injury: characterization of the "time window of protection'. 1996 Brain Res. pmid:9001730
Gyure WL A rapid screening method for blood glucose estimation. 1977 Am. J. Clin. Pathol. pmid:900068
Kalbhen DA and Schiller G [Roentgenologic determination of degenerative joint diseases in a new animal experiment arthrosis model]. 1977 May-Jun Z Rheumatol pmid:899298