Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Dadlez M and Kim PS | Rapid formation of the native 14-38 disulfide bond in the early stages of BPTI folding. | 1996 | Biochemistry | pmid:8973187 |
Dux E et al. | Early ultrastructural changes after brief histotoxic hypoxia in cultured cortical and hippocampal CA1 neurons. | 1996 | Acta Neuropathol. | pmid:8960310 |
Guzzo A et al. | Analysis of the region between amino acids 30 and 42 of intact UmuD by a monocysteine approach. | 1996 | J. Bacteriol. | pmid:8955415 |
Tozawa K et al. | Unusual pKa of the carboxylate at the putative catalytic position of the thermophilic F1-ATPase beta subunit determined by 13C-NMR. | 1996 | FEBS Lett. | pmid:8941727 |
Leif RC et al. | A procedure for dissociating Ayre scrape samples. | 1977 | J. Histochem. Cytochem. | pmid:894001 |
Wells JE and Russell JB | The effect of growth and starvation on the lysis of the ruminal cellulolytic bacterium Fibrobacter succinogenes. | 1996 | Appl. Environ. Microbiol. | pmid:8919795 |
Saransaari P and Oja SS | Taurine and neural cell damage. Transport of taurine in adult and developing mice. | 1996 | Adv. Exp. Med. Biol. | pmid:8915386 |
Malek A et al. | Energy charge monitoring via magnetic resonance spectroscopy 31P in the perfused human placenta: effects of cadmium, dinitrophenol and iodoacetate. | 1996 | Placenta | pmid:8899879 |
Hartmund T and Gesser H | Cardiac force and high-energy phosphates under metabolic inhibition in four ectothermic vertebrates. | 1996 | Am. J. Physiol. | pmid:8897986 |
Tabillion R and Kaltwasser H | [Energy-dependent 63Ni-uptake by Alcaligenes eutrophus strains H1 and H16 (author's transl)]. | 1977 | Arch. Microbiol. | pmid:889383 |
Webster DR and Oxford MG | Regulation of cytoplasmic tubulin carboxypeptidase activity in vitro by cations and sulfhydryl-modifying compounds. | 1996 | J. Cell. Biochem. | pmid:8867817 |
Zhang ZY et al. | Catalytic function of the conserved hydroxyl group in the protein tyrosine phosphatase signature motif. | 1995 | Biochemistry | pmid:8845365 |
Kelly MJ and Richardson W | Possible mechanisms for the protective action of alpha-tocopherol in vascular hypoxia. | 1996 | J Auton Pharmacol | pmid:8842869 |
Mackert BM et al. | Anoxia in vitro does not induce neuronal swelling or death. | 1996 | J. Neurol. Sci. | pmid:8836970 |
Xu M and Akabas MH | Identification of channel-lining residues in the M2 membrane-spanning segment of the GABA(A) receptor alpha1 subunit. | 1996 | J. Gen. Physiol. | pmid:8833341 |
Chew A et al. | Mutations in a putative zinc-binding domain inactivate the mitochondrial intermediate peptidase. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8831696 |
Collinson IR et al. | The F1F0-ATPase complex from bovine heart mitochondria: the molar ratio of the subunits in the stalk region linking the F1 and F0 domains. | 1996 | Biochemistry | pmid:8823202 |
Godeas C et al. | Rat testis mitochondrial phospholipid hydroperoxide glutathione peroxidase does not protect endogenous vitamin E against Fe2+-induced (lipo)peroxidation. | 1996 | Biochem. Mol. Med. | pmid:8812743 |
Wu Y et al. | Changes in membrane properties during energy depletion-induced cell injury studied with fluorescence microscopy. | 1996 | Biophys. J. | pmid:8804592 |
Han Z et al. | DNA-dependent protein kinase is a target for a CPP32-like apoptotic protease. | 1996 | J. Biol. Chem. | pmid:8798786 |
Umbach AL and Siedow JN | The reaction of the soybean cotyledon mitochondrial cyanide-resistant oxidase with sulfhydryl reagents suggests that alpha-keto acid activation involves the formation of a thiohemiacetal. | 1996 | J. Biol. Chem. | pmid:8798784 |
Sammut EB and Kannegieter NJ | Use of sodium monoiodoacetate to fuse the distal hock joints in horses. | 1995 | Aust. Vet. J. | pmid:8787522 |
Barrigon S et al. | Characterization of the calcium overload in cultured neonatal rat cardiomyocytes under metabolic inhibition. | 1996 | J. Mol. Cell. Cardiol. | pmid:8782074 |
Hegy GB et al. | Carboxymethylation of the human estrogen receptor ligand-binding domain-estradiol complex: HPLC/ESMS peptide mapping shows that cysteine 447 does not react with iodoacetic acid. | 1996 | Steroids | pmid:8776799 |
Kanaani J et al. | Probing the active site of Tritrichomonas foetus hypoxanthine-guanine-xanthine phosphoribosyltransferase using covalent modification of cysteine residues. | 1996 | Eur. J. Biochem. | pmid:8774725 |
Wu Y et al. | Alterations in reactive oxygen, pH, and calcium in astrocytoma cells during lethal injury. | 1996 | Am. J. Physiol. | pmid:8772436 |
Ito Y et al. | Oxidative stress increases glyceraldehyde-3-phosphate dehydrogenase mRNA levels in isolated rabbit aorta. | 1996 | Am. J. Physiol. | pmid:8769737 |
Ballanyi K et al. | Functional relevance of anaerobic metabolism in the isolated respiratory network of newborn rats. | 1996 | Pflugers Arch. | pmid:8764977 |
Lawson SL et al. | Effects of both shortening and lengthening the active site nucleophile of Bacillus circulans xylanase on catalytic activity. | 1996 | Biochemistry | pmid:8756474 |
Dekker LR et al. | Intracellular Ca2+, intercellular electrical coupling, and mechanical activity in ischemic rabbit papillary muscle. Effects of preconditioning and metabolic blockade. | 1996 | Circ. Res. | pmid:8756000 |
Ishimizu T et al. | Identification of histidine 31 and cysteine 95 in the active site of self-incompatibility associated S6-RNase in Nicotiana alata. | 1995 | J. Biochem. | pmid:8749320 |
Bersinger NA et al. | Pregnancy-associated plasma protein A (PAPP-A): measurement by highly sensitive and specific enzyme immunoassay, importance of first-trimester serum determinations, and stability studies. | 1995 | Reprod. Fertil. Dev. | pmid:8743141 |
Liang CS | Metabolic control of circulation. Effects of iodoacetate and fluoroacetate. | 1977 | J. Clin. Invest. | pmid:874090 |
Morel MH and Bonicel J | Determination of the number of cysteine residues in high molecular weight subunits of wheat glutenin. | 1996 | Electrophoresis | pmid:8740165 |
Springer TA et al. | Submit and disulfide structure of monomeric and dimeric forms of detergent-soluble HLA antigens. | 1977 | J. Biol. Chem. | pmid:873911 |
Six S et al. | Reactivity of the N-terminal cysteine residues in active and inactive forms of FNR, and O2-responsive, Fe containing transcriptional regulator of Escherichia coli. | 1996 | J. Inorg. Biochem. | pmid:8729797 |
Hunter ES and Tugman JA | Inhibitors of glycolytic metabolism affect neurulation-staged mouse conceptuses in vitro. | 1995 | Teratology | pmid:8711618 |
Vospel'nikova ND et al. | [Structural studies on D-glyceraldehyde-3-phosphate dehydrogenase from rat skeletal muscle]. | 1977 | Biokhimiia | pmid:870089 |
Barnett DK and Bavister BD | Inhibitory effect of glucose and phosphate on the second cleavage division of hamster embryos: is it linked to metabolism? | 1996 | Hum. Reprod. | pmid:8671182 |
Boehm EA et al. | The utilisation of creatine and its analogues by cytosolic and mitochondrial creatine kinase. | 1996 | Biochim. Biophys. Acta | pmid:8664304 |
Reaven E et al. | Intracellular events in the "selective" transport of lipoprotein-derived cholesteryl esters. | 1996 | J. Biol. Chem. | pmid:8663101 |
Andrés MI et al. | Comparative effects of the metabolic inhibitors 2,4-dinitrophenol and iodoacetate on mouse neuroblastoma cells in vitro. | 1996 | Toxicology | pmid:8658553 |
Balter NJ and Schwartz SL | Accumulation of norepinephrine by macrophages and relationships to known uptake processes. | 1977 | J. Pharmacol. Exp. Ther. | pmid:864600 |
Matsushita M et al. | Isoflurane preserves adenosine triphosphate levels in anoxic isolated rat hepatocytes by stimulating glycolytic adenosine triphosphate formation. | 1996 | Anesth. Analg. | pmid:8638802 |
Nawaz MS et al. | Physical, biochemical, and immunological characterization of a thermostable amidase from Klebsiella pneumoniae NCTR 1. | 1996 | J. Bacteriol. | pmid:8636044 |
Jones MD et al. | Refolding and oxidation of recombinant human stem cell factor produced in Escherichia coli. | 1996 | J. Biol. Chem. | pmid:8626682 |
Grifantini R et al. | Topological mapping of the cysteine residues of N-carbamyl-D-amino-acid amidohydrolase and their role in enzymatic activity. | 1996 | J. Biol. Chem. | pmid:8621596 |
Wu L and Zhang ZY | Probing the function of Asp128 in the lower molecular weight protein-tyrosine phosphatase-catalyzed reaction. A pre-steady-state and steady-state kinetic investigation. | 1996 | Biochemistry | pmid:8611532 |
Peltier JB and Rossignol M | Auxin-induced differential sensitivity of the H+-ATPase in plasma membrane subfractions from tobacco cells. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8605015 |
Hojring N and Svensmark O | Carboxylesterases of human brain extract. Purification and properties of a butyrylesterase. | 1977 | Biochim. Biophys. Acta | pmid:857894 |
Rheins MS and Filppi JA | Iodoacetate-induced inhibition and enhancement of spontaneous leukemia in AKR mice. | 1977 | J. Natl. Cancer Inst. | pmid:857029 |
Law RO | Factors affecting the distribution of chloride ions in rat renal outer medulla. | 1977 | J. Physiol. (Lond.) | pmid:856997 |
Walsh SB and Mantle TJ | Modification of mouse liver glutathione S-transferase Pi by iodoacetic acid. | 1995 | Biochem. Soc. Trans. | pmid:8566383 |
Hoban DJ and Lyric RM | Glutamate uptake in Thiobacillus novellus. | 1977 | Can. J. Microbiol. | pmid:856422 |
Lash LH et al. | ATP depletion by iodoacetate and cyanide in renal distal tubular cells. | 1996 | J. Pharmacol. Exp. Ther. | pmid:8558430 |
Raia CA et al. | Activation of Sulfolobus solfataricus alcohol dehydrogenase by modification of cysteine residue 38 with iodoacetic acid. | 1996 | Biochemistry | pmid:8555238 |
Ionescu E and Buresová O | Failure to elicit conditioned taste aversion by severe poisoning. | 1977 | Pharmacol. Biochem. Behav. | pmid:854518 |
Ma L et al. | Multiphasic modulation of signal transduction into T lymphocytes by monoiodoacetic acid as a sulfhydryl reagent. | 1995 | J. Cell. Biochem. | pmid:8530534 |
Chan CB et al. | Evidence for defective glucose sensing by islets of fa/fa obese Zucker rats. | 1993 | Can. J. Physiol. Pharmacol. | pmid:8513432 |
Kembhavi AA et al. | The two cysteine endopeptidases of legume seeds: purification and characterization by use of specific fluorometric assays. | 1993 | Arch. Biochem. Biophys. | pmid:8512309 |
Koss KL et al. | Mg2+ buffering in cultured chick ventricular myocytes: quantitation and modulation by Ca2+. | 1993 | Am. J. Physiol. | pmid:8498485 |
Yamamoto F and Honda Y | Effects of intravenous iodoacetate and iodate on pH outside rod photoreceptors in the cat retina. | 1993 | Invest. Ophthalmol. Vis. Sci. | pmid:8491551 |
Chen LY et al. | Deoxyribonuclease of Syncephalastrum racemosum--enzymatic properties and molecular structure. | 1993 | Arch. Biochem. Biophys. | pmid:8489265 |
Yamada T et al. | 31P nuclear magnetic resonance studies on the glycogenolysis regulation in resting and contracting frog skeletal muscle. | 1993 | J. Physiol. (Lond.) | pmid:8487196 |
Kaloyianni M et al. | Effect of adenosine on glucose metabolism of Rana ridibunda erythrocytes. | 1993 | J. Exp. Biol. | pmid:8487000 |
Villalba JM et al. | Thiol groups are involved in NADH-ascorbate free radical reductase activity of rat liver plasma membrane. | 1993 | Biochem. Biophys. Res. Commun. | pmid:8484777 |
Pinto RA et al. | Uptake of pulmonary surfactant protein C into adult rat lung lamellar bodies. | 1993 | J. Appl. Physiol. | pmid:8482637 |
Allam AM et al. | Amylase of the thermophilic actinomycete Thermomonospora vulgaris. | 1975 | Z. Allg. Mikrobiol. | pmid:848 |
L'Hostis C et al. | Active transport of L-proline in the protozoan parasite Trypanosoma brucei brucei. | 1993 | Biochem. J. | pmid:8471048 |
Park YC and Goodman WG | Analysis and modification of thiols in the hemolymph juvenile hormone binding protein of Manduca sexta. | 1993 | Arch. Biochem. Biophys. | pmid:8470889 |
Sun FF et al. | Degradation of membrane phospholipids in the cultured human astroglial cell line UC-11MG during ATP depletion. | 1993 | Biochem. Pharmacol. | pmid:8461044 |
Crouzoulon G | [Kinetic properties of the fructose influx across the brush border of the rat jejunum. Effects of a diet rich in fructose]. | 1978 | Arch. Int. Physiol. Biochim. | pmid:84551 |
Sethi R et al. | Characteristics and mechanisms of tachyphylaxis of cardiac contractile response to insulin. | 1993 | Int. J. Cardiol. | pmid:8454373 |
Edwards RB | Accumulation of taurine by cultured retinal pigment epithelium of the rat. | 1977 | Invest. Ophthalmol. Vis. Sci. | pmid:844977 |
Salamino F et al. | Site-directed activation of calpain is promoted by a membrane-associated natural activator protein. | 1993 | Biochem. J. | pmid:8439288 |
Suzuki R and Anderson PJ | A temperature dependent action of fluoride on aqueous outflow facility of the calf eye. | 1993 | Curr. Eye Res. | pmid:8436006 |
Maublant JC et al. | Uptake of technetium-99m-teboroxime in cultured myocardial cells: comparison with thallium-201 and technetium-99m-sestamibi. | 1993 | J. Nucl. Med. | pmid:8429344 |
Lewis CT et al. | Identification of vicinal thiols of phosphoenolpyruvate carboxykinase (GTP). | 1993 | J. Biol. Chem. | pmid:8420937 |
Oleinikov AV et al. | Structural and functional domains of Escherichia coli ribosomal protein L7/L12. The hinge region is required for activity. | 1993 | J. Biol. Chem. | pmid:8419370 |
Kaur S et al. | Effect of pH and sodium ions on intestinal uptake of lysine in rats. | 1993 | Indian J. Exp. Biol. | pmid:8406600 |
Baum KF et al. | Purine nucleoside and nucleobase cell membrane transport in Giardia lamblia. | 1993 Sep-Oct | J. Eukaryot. Microbiol. | pmid:8401476 |
Roberts EL | Glycolysis and recovery of potassium ion homeostasis and synaptic transmission in hippocampal slices after anoxia or stimulated potassium release. | 1993 | Brain Res. | pmid:8396493 |
Hunt J et al. | Redox potentials of milk xanthine dehydrogenase. Room temperature measurement of the FAD and 2Fe/2S center potentials. | 1993 | J. Biol. Chem. | pmid:8395516 |
Perks AM et al. | Reabsorption of lung liquid produced by 2,4-dinitrophenol in in vitro lungs from fetal guinea pigs. | 1993 | Can. J. Physiol. Pharmacol. | pmid:8390326 |
Versée V and Barel AO | Rat alpha-foetoprotein. Purification, physicochemical characterization, oestrogen-binding properties and chemical modification of the thiol group. | 1978 | Biochem. J. | pmid:83865 |
Nakamura K et al. | Glycolysis is necessary to preserve myocardial Ca2+ homeostasis during beta-adrenergic stimulation. | 1993 | Am. J. Physiol. | pmid:8384419 |
Kondo Y et al. | Direct evidence for the absence of active Na+ reabsorption in hamster ascending thin limb of Henle's loop. | 1993 | J. Clin. Invest. | pmid:8380816 |
Otero de Bengtsson MS et al. | Involvement of a disulfide bond in the binding of flunitrazepam to the benzodiazepine receptor from bovine cerebral cortex. | 1993 | J. Neurochem. | pmid:8380435 |
Fontana M et al. | The inhibition of bovine serum amine oxidase by cysteamine. | 1993 | Physiol Chem Phys Med NMR | pmid:8378438 |
Leong JM et al. | A 76-amino acid disulfide loop in the Yersinia pseudotuberculosis invasin protein is required for integrin receptor recognition. | 1993 | J. Biol. Chem. | pmid:8376409 |
Zhang ZY and Dixon JE | Active site labeling of the Yersinia protein tyrosine phosphatase: the determination of the pKa of the active site cysteine and the function of the conserved histidine 402. | 1993 | Biochemistry | pmid:8369304 |
Greenwood SL et al. | Transtrophoblast and microvillus membrane potential difference in mature intermediate human placental villi. | 1993 | Am. J. Physiol. | pmid:8368275 |
Brooks SP and Storey KB | Control of glycolytic enzyme binding: effect of changing enzyme substrate concentrations on in vivo enzyme distributions. | 1993 | Mol. Cell. Biochem. | pmid:8350861 |
Igisu H et al. | Highly cooperative inhibition of acetylcholinesterase by pentachlorophenol in human erythrocytes. | 1993 | Biochem. Pharmacol. | pmid:8347128 |
Mayorga LS et al. | Effect of pH and ATP on the equilibrium density of lysosomes. | 1993 | J. Cell. Physiol. | pmid:8344987 |
Liu SQ et al. | Identification of the reactive cysteine residue in human placenta aldose reductase. | 1993 | Biochim. Biophys. Acta | pmid:8343525 |
van Osch GJ et al. | In vivo quantification of proteoglycan synthesis in articular cartilage of different topographical areas in the murine knee joint. | 1993 | J. Orthop. Res. | pmid:8340822 |
Dunham J et al. | Prolonged effect of iodoacetate on articular cartilage and its modification by an anti-rheumatic drug. | 1993 | Int J Exp Pathol | pmid:8334078 |
Russell JB | Effect of amino acids on the heat production and growth efficiency of Streptococcus bovis: balance of anabolic and catabolic rates. | 1993 | Appl. Environ. Microbiol. | pmid:8328799 |
Teng H et al. | Conserved cysteine residues of histidinol dehydrogenase are not involved in catalysis. Novel chemistry required for enzymatic aldehyde oxidation. | 1993 | J. Biol. Chem. | pmid:8314784 |