Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kozlov VK | [Lysosome-like alpha-granules of thrombocytes: detection by acridine orange treatment, properties and transformations during the course of blood coagulation reactions]. | 1975 | Tsitologiia | pmid:51527 |
Pegg DE et al. | The mechanism of action of retrograde oxygen persufflation in renal preservation. | 1989 | Transplantation | pmid:2547255 |
Ptak W et al. | Cytotoxic macrophage in graft-versus-host reaction. | 1975 | Transplantation | pmid:235161 |
Barodka V et al. | Nitroprusside inhibits calcium-induced impairment of red blood cell deformability. | 2014 | Transfusion | pmid:23781865 |
Dawson RB et al. | Blood preservation. XLIII. Studies on the ascorbate mechanisms of maintaining red cell 2,3-DPG. | 1980 May-Jun | Transfusion | pmid:7385326 |
Dosio F et al. | Immunotoxins and anticancer drug conjugate assemblies: the role of the linkage between components. | 2011 | Toxins (Basel) | pmid:22069744 |
Siemon H et al. | Vanadium increases selective K+-permeability in human erythrocytes. | 1981-1982 | Toxicology | pmid:7342369 |
Andrés MI et al. | Comparative effects of the metabolic inhibitors 2,4-dinitrophenol and iodoacetate on mouse neuroblastoma cells in vitro. | 1996 | Toxicology | pmid:8658553 |
Cojocel C and Hook JB | Effects of acute exposures to gentamicin on renal handling of proteins. | 1983 | Toxicology | pmid:6648982 |
Si EC et al. | Iodoacetic acid and related sulfhydryl reagents fail to inhibit cell-cell communication: mechanisms of immunotoxicity in vitro. | 1987 | Toxicology | pmid:3105120 |
Foulkes EC | Further findings on the mechanism of cadmium uptake by intestinal mucosal cells (step 1 of Cd absorption). | 1991 | Toxicology | pmid:1771634 |
Mitchell DB et al. | Role of glutathione depletion in the cytotoxicity of acetaminophen in a primary culture system of rat hepatocytes. | 1985 | Toxicology | pmid:4060164 |
Smith LL et al. | Factors affecting the efflux of paraquat from rat lung slices. | 1981 | Toxicology | pmid:7233444 |
Angevine LS and Mehendale HM | Chlorphentermine uptake by rabbit lung slices. | 1980 | Toxicology | pmid:7414614 |
Puntel RL et al. | Mitochondrial dysfunction induced by different organochalchogens is mediated by thiol oxidation and is not dependent of the classical mitochondrial permeability transition pore opening. | 2010 | Toxicol. Sci. | pmid:20573786 |
Kamendulis LM and Corcoran GB | Independence and additivity of cultured hepatocyte killing by Ca2+ overload and ATP depletion. | 1992 | Toxicol. Lett. | pmid:1488777 |
Shimada H et al. | The effects of sulfhydryl blockers and metal ions on nickel accumulation by rat primary hepatocyte cultures. | 2000 | Toxicol. Lett. | pmid:11137313 |
Eide I and Syversen TL | Uptake of elemental mercury by brain in relation to concentration of glutathione and activity of glutathione peroxidase. | 1983 | Toxicol. Lett. | pmid:6623515 |
Maduagwu EN | Differential effects on the cyanogenic glycoside content of fermenting cassava root pulp by beta-glucosidase and microbial activities. | 1983 | Toxicol. Lett. | pmid:6404010 |
Cannon JR et al. | The effects of fructose on adenosine triphosphate depletion following mitochondrial dysfunction and lethal cell injury in isolated rat hepatocytes. | 1991 | Toxicol. Appl. Pharmacol. | pmid:2020968 |