Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Pain D010146 64 associated lipids
Lung Neoplasms D008175 171 associated lipids
Wounds and Injuries D014947 20 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Sarcoma 180 D012510 21 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Osteoarthritis D010003 4 associated lipids
Coronary Disease D003327 70 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Glioma D005910 112 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Lymphoma D008223 18 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Brain Edema D001929 20 associated lipids
Stroke D020521 32 associated lipids
Starvation D013217 47 associated lipids
Hypocalcemia D006996 12 associated lipids
Brain Ischemia D002545 89 associated lipids
Epilepsy D004827 35 associated lipids
Nerve Degeneration D009410 53 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Hyperalgesia D006930 42 associated lipids
Thrombocytopenia D013921 15 associated lipids
Hyperlipidemias D006949 73 associated lipids
Rickets D012279 6 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
Byssinosis D002095 11 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Vitamin D Deficiency D014808 13 associated lipids
Vascular Diseases D014652 16 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Blindness D001766 6 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Temporomandibular Joint Disorders D013705 4 associated lipids
Arthralgia D018771 8 associated lipids
Osteophyte D054850 2 associated lipids
Glycogen Storage Disease D006008 4 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Retinitis D012173 4 associated lipids
Theileriasis D013801 7 associated lipids
Muscle Cramp D009120 3 associated lipids
Rigor Mortis D012298 1 associated lipids
Thrombophilia D019851 6 associated lipids
Cumulative Trauma Disorders D012090 2 associated lipids
Monckeberg Medial Calcific Sclerosis D050380 1 associated lipids
Clonorchiasis D003003 1 associated lipids
Osteoarthritis, Spine D055013 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

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Authors Title Published Journal PubMed Link
Sidorenkov IV and Sharaev PN [Effect of cholesterol, monoiodoacetate and glycerophosphate on tissue content of hexosamines]. 1972 Jan-Feb Vopr. Med. Khim. pmid:5060340
Garcia AG and Kirpekar SM Release of noradrenaline from the cat spleen by sodium deprivation. 1973 Br. J. Pharmacol. pmid:4124979
Campbell IC and Todrick A On the pharmacology and biochemistry of the amine-uptake mechanism in human blood platelets. 1973 Br. J. Pharmacol. pmid:4152219
Starkey PM and Barrett AJ Inhibition by alpha-macroglobulin and other serum proteins. 1973 Biochem. J. pmid:4198623
Sjöholm I and Ljungdahl M Protein A from Staphylococcus aureus. XVI. Alkylation with iodoacetic acid at different pH-values. 1973 Immunochemistry pmid:4200118
Kirpekar SM et al. Metabolic and ionic requirements for the intra-axonal transport of noradrenaline in the cat hypogastric nerve. 1973 J. Physiol. (Lond.) pmid:4119622
Tamai A et al. [ERP of experimental retinitis pigmentosa--effects of intravenous injection of monoiodoacetic acid on the pigmented rabbit ERP (author's transl)]. 1973 Nippon Ganka Gakkai Zasshi pmid:4799593
Stewart GR and Stevenson KJ The isolation and partial characterization of ribonuclease A from Bison bison. 1973 Biochem. J. pmid:4772270
Kapoor CL et al. Uptake and release of bilirubin by skin. 1973 Biochem. J. pmid:4772626
Sidorenkov IV and Sharaev PN [Effect of cholesterol and monoiodoacetate on hexosamine synthetase activity and also on the content of hexosamines and hexuronic acids in the aortal wall]. 1973 Biull Eksp Biol Med pmid:4774434
Crawhall JC and Purkiss P Transport of methionine and proline by rat liver slices and the effect of certain hormones. 1973 Biochem. J. pmid:4359105
Bowman RH et al. Furosemide, ethacrynic acid, and iodoacetate on function and metabolism in perfused rat kidney. 1973 Am. J. Physiol. pmid:4686497
Rheins MS and Barker AD Therapeutic and immunologic effects of iodoacetate in mature AKR mice. 1973 Experientia pmid:4575260
Barker AD et al. Immunologic responsiveness of young AKR mice to iodoacetate and to iodoacetate-treated tumor cells. 1973 Immunol. Commun. pmid:4583065
Hwang UK and Connors NA The effect of iodoacetate on the developing chick metanephros. 1973 Experientia pmid:4729463
Bradbury AF and Smyth DG The use of 3-bromopropionic acid for the determination of protein thiol groups. 1973 Biochem. J. pmid:4737322
Bryce CF and Crichton RR The catalytic activity of horse spleen apoferritin. Preliminary kinetic studies and the effect of chemical modification. 1973 Biochem. J. pmid:4737426
Poole B and Wibo M Protein degradation in cultured cells. The effect of fresh medium, fluoride, and iodoacetate on the digestion of cellular protein of rat fibroblasts. 1973 J. Biol. Chem. pmid:4737734
Ling GN and Ochsenfeld MM Mobility of potassium ion in frog muscle cells, both living and dead. 1973 Science pmid:4714293
Harada M and Irie M Alkylation of ribonuclease from Aspergillus saitoi with iodoacetate and iodoacetamide. 1973 J. Biochem. pmid:4720055
Miller TJ Cleft palate formation: the effects of fasting and iodoacetic acid on mice. 1973 Teratology pmid:4725547
Canfield P and Maréchal G Equilibrium of nucleotides in frog sartorius muscle during an isometric tetanus at 20 degrees C. 1973 J. Physiol. (Lond.) pmid:4543341
Canfield P et al. Energy balance in frog sartorius muscle during an isometric tetanus at 20 degrees C. 1973 J. Physiol. (Lond.) pmid:4759678
Hasilik A Perturbation of growth and metabolism in Candida albicans by 4-bromobenzyl isothiocyanate and iodoacetate. 1973 Jan-Feb Z Naturforsch C pmid:4148805
Fischbarg J and Lim JJ Role of cations, anions and carbonic anhydrase in fluid transport across rabbit corneal endothelium. 1974 J. Physiol. (Lond.) pmid:4215880
Ponte F et al. Iodoacetic acid influence on the aerobic glycolysis in surviving retinae of normal rats and of carriers of inherited retinal degeneration. 1974 Ophthalmologica pmid:4852565
Ahtee L et al. Transport of taurine by normal human blood platelets. 1974 Br. J. Pharmacol. pmid:4451820
Cooke RD et al. Calcium and thiol reactivity of human plasma clotting factor XIII. 1974 Biochem. J. pmid:4463957
Cooke RD and Holbrook JJ The calcium-induced dissociation of human plasma clotting factor XIII. 1974 Biochem. J. pmid:4477004
Thorn W et al. [Carbohydrate turn over, energy deficit and the formation of plasma polyps within the placenta after poisoning with monoiodineacetate and sodium fluoride (author's transl)]. 1974 Arch Gynakol pmid:4406633
Kaufmann P et al. [The morphology of the guinea pig placenta after poisoning with monoiodineacetate and fluoride (author's transl)]. 1974 Arch Gynakol pmid:4406634
Serrano R and Reeves RE Glucose transport in Entamoeba histolytica. 1974 Biochem. J. pmid:4376956
Goetzl EJ and Austen KF Stimulation of human neutrophil leukocyte aerobic glucose metabolism by purified chemotactic factors. 1974 J. Clin. Invest. pmid:11344574
Moreland DE et al. Adenosine Phosphates in Germinating Radish (Raphanus sativus L.) Seeds. 1974 Plant Physiol. pmid:16658928
Dmitriev AP and GrodzinskiÄ­ DM [Effect of radiosensitizer (monoiodoacetate) on the recovery of sublethally damaged cells of blue-green alga, Anacystis nidulans]. 1974 May-Jun Radiobiologiia pmid:4211026
Palcic B and Skarsgard LD Absence of ultrafast processes of repair of single-strand breaks in mammalian DNA. 1975 Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. pmid:804459
Hazeu W Some cultural and physiological aspects of methane-utilizing bacteria. 1975 Antonie Van Leeuwenhoek pmid:808162
Gleisner JM and Blakley RL The structure of dihydrofolate reductase. Identification of methionine residues carboxymethylated by iodoacetate with loss of catalytic activity. 1975 Eur. J. Biochem. pmid:809271
Ide T et al. Recovery of a DNA-protein complex in cultured mammalian cells from damage caused by 4-nitroquinoline 1-oxide. 1975 Cancer Res. pmid:810243
Borel JF and Feurer C Chemotaxis of rabbit macrophages in vitro: inhibition by drugs. 1975 Experientia pmid:814017
Hill EJ et al. Covalent binding of 3-pyridinealdehyde nicotinamide adenine dinucleotide and substrate to glyceraldehyde 3-phosphate dehydrogenase. 1975 J. Biol. Chem. pmid:163256
Thiry L et al. Comparison of the immunogenicity of hamster cells transformed by adenovirus and Herpes simplex virus. 1975 Cancer Res. pmid:163694
Lange LG et al. The role of arginyl residues in directing carboxymethylation of horse liver alcohol dehydrogenase. 1975 Biochemistry pmid:167828
Zylka JM and Plagemann PG Purine and pyrimidine transport by cultured Novikoff cells. Specificities and mechanism of transport and relationship to phosphoribosylation. 1975 J. Biol. Chem. pmid:168203
Romeo D et al. Concanavalin A as a probe for studying the mechanism of metabolic stimulation of leukocytes. 1975 Adv. Exp. Med. Biol. pmid:168745
Byers LD and Koshland DE The specificity of induced conformational changes. The case of yeast glyceraldehyde-3-phosphate dehydrogenase. 1975 Biochemistry pmid:169882
Mende TJ and Moreno M A heat stable paraoxonase (O,O-diethyl O-p-nitrophenyl phosphate O-p-nitrophenyl hydrolase) from Russell's viper venom. 1975 Biochemistry pmid:169891
Laiho KU and Trump BF Mitochondrial changes, ion and water shifts in the cellular injury of ehrlich ascites tumor cells. 1975 Beitr Pathol pmid:170904
Hashimoto S et al. Dependence of platelet adenyl cyclase system on oxidative phosphorylation. 1975 Thromb Diath Haemorrh pmid:171798
Shane B and Stokstad EL Transport and metabolism of folates by bacteria. 1975 J. Biol. Chem. pmid:234963
Ptak W et al. Cytotoxic macrophage in graft-versus-host reaction. 1975 Transplantation pmid:235161
Polgár L Ion-pair formation as a source of enhanced reactivity of the essential thiol group of D-glyceraldehyde-3-phosphate dehydrogenase. 1975 Eur. J. Biochem. pmid:235434
Bradbury JH and Norton RS Proton-magnetic-resonance spectroscopic study of the histidine residues of bovine alpha-lactalbumin. 1975 Eur. J. Biochem. pmid:237758
Klinman JP The interaction of an epoxide with yeast alcohol dehydrogenase: evidence for binding and the modification of two active site cysteines by styrene oxide. 1975 Biochemistry pmid:238561
Volfová O Studies on methanol - oxidizing yeast. III. Enzyme. 1975 Folia Microbiol. (Praha) pmid:240764
Ehrlich RS and Colman RF Coenzyme binding by native and chemically modified pig heart triphosphopyridine nucleotide dependent isocitrate dehydrogenase. 1975 Biochemistry pmid:241396
Kundu AK and Manna S Purification and characterization of extracellular proteinases of Aspergillus oryzae. 1975 Appl Microbiol pmid:242254
Kuo SC and Lampen JO Action of cytochalasin A, a sulfhydryl-reactive agent, on sugar metabolism and membrane-bound adenosine triphosphatase of yeast. 1975 Biochim. Biophys. Acta pmid:124588
Mori M A study on the nuclear extrusion of mammalian erythroblast. 1975 Acta Med. Okayama pmid:127510
Bárány M et al. Structural changes in myosin during contraction and the state of ATP in the intact frog muscle. 1975 J. Supramol. Struct. pmid:127883
Wright WE and Hayflick L Contributions of cytoplasmic factors to in vitro cellular senescence. 1975 Fed. Proc. pmid:162798
Rheins MS et al. Effect of iodoacetate on the bone marrow immunocompetence of AKR mice. 1975 Cancer Res. pmid:1093673
Spoerl E et al. Reversible permeability changes in the membrane of a yeast cell sugar compartment. 1975 J. Membr. Biol. pmid:1095751
Urist MR et al. A chemosterilized antigen-extracted autodigested alloimplant for bone banks. 1975 Arch Surg pmid:1096848
Murphy DL et al. Occurrence, transport, and storage of octopamine in human thrombocytes. 1975 Clin. Pharmacol. Ther. pmid:1102236
Zervos C and Adams E Hydroxyproline-2-epimerase of Pseudomonas: active-site peptides. 1975 Mol. Cell. Biochem. pmid:1165763
Ayala E and Canonico PG Aminoisobutyric acid transport in primary cultures of normal adult rat hepatocytes. 1975 Proc. Soc. Exp. Biol. Med. pmid:1166067
Walker WS and Demus A Antibody-dependent cytolysis of chicken erythrocytes by an in vitro-established line of mouse peritoneal macrophages. 1975 J. Immunol. pmid:1167563
Massaro D In vivo protein secretion by lung. Evidence for active secretion and interspecies differences. 1975 J. Clin. Invest. pmid:1173812
Rudnick G and Abeles RH Reaction mechanism and structure of the active site of proline racemase. 1975 Biochemistry pmid:1174513
Petitpierre-Gabathuler MP and Ryser HJ Cellular uptake of soluble and aggregated ferritin: distinction between pinocytosis and phagocytosis. 1975 J. Cell. Sci. pmid:1176545
Jaspers HT and van Steveninck J Transport-associated phosphorylation of 2-deoxy-D-glucose in Saccharomyces fragilis. 1975 Biochim. Biophys. Acta pmid:1182170
Siflinger A et al. Uptake of 125I albumin by the endothelial surface of the isolated dog common carotid artery: effect of certain physical factors and metabolic inhibitors. 1975 Cardiovasc. Res. pmid:1182724
Marbach EP et al. Sodium iodoacetate as an antiglycolytic agent in blood samples. 1975 Clin. Chem. pmid:1183004
Yip YK et al. Studies on catalytic properties of purified high molecular weight pancreatic lipase. 1975 Proc. Soc. Exp. Biol. Med. pmid:1144458
Chicheportiche R et al. Structure-function relationship in the binding of snake neurotoxins to the torpedo membrane receptor. 1975 Biochemistry pmid:1148159
Ramp WK et al. Effects of ethanol on chicks in vivo and on chick embryo tibiae in organ culture. 1975 Calcif Tissue Res pmid:1148882
Hicks EP and Ramp WK The effects of fluoride on the mineralization of embryonic chick tibiae in organ culture. 1975 Calcif Tissue Res pmid:1148883
Kishida F et al. A type kappa Bence Jones protein containing a cysteinyl residue in the variable region. 1975 J. Biochem. pmid:1150631
Trinchieri G and De Marchi M Antibody-dependent cell-mediated cytotoxicity in humans. II. Energy requirement. 1975 J. Immunol. pmid:1151059
Essenberg MK and Cooper RA Two ribose-5-phosphate isomerases from Escherichia coli K12: partial characterisation of the enzymes and consideration of their possible physiological roles. 1975 Eur. J. Biochem. pmid:1104357
Gleisner JM and Blakley RL The structure of dihydrofolate reductase. I. Inactivation of bacterial dihydrofolate reductase concomitant with modification of a methionine residue at the active site. 1975 J. Biol. Chem. pmid:1112818
Edwards RH et al. Metabolic changes associated with the slowing of relaxation in fatigued mouse muscle. 1975 J. Physiol. (Lond.) pmid:1185665
Lasch J Fluorescence and chemical reactivity as empirical indices of matrix-induced alterations in immobilized enzymes. 1975 Acta Biol. Med. Ger. pmid:1189829
Poole DT et al. Rabbit muscle triosephosphate isomerase: activity and inactivation by sulfhydryl reagents as affected by enzyme concentration. 1975 Proc. Soc. Exp. Biol. Med. pmid:1129283
Steinberg H et al. Depression of pulmonary 5-hydroxytryptamine uptake by metabolic inhibitors. 1975 Am. J. Physiol. pmid:1130533
Gardner ML Inhibition of iodoacetate of 'downhill' transport of sodium ions across isolated rat small intestine. 1975 Biochem. Soc. Trans. pmid:1132553
Blendstrup K et al. Characteristics of renin release from isolated superfused glomeruli in vitro. 1975 J. Physiol. (Lond.) pmid:1133791
Knock FE et al. Effects of selected sulfhydryl inhibitors on nonhistone chromosomal proteins of HeLa cells. 1975 Oncology pmid:1228540
Zeppezauer E et al. Carboxymethylation of horse-liver alcohol dehydrogenase in the crystalline state. The active-site zinc region and general anion-binding site of the enzyme correlated in primary and teritiary structures. 1975 Eur. J. Biochem. pmid:1237402
Blaustein MP and Goldring JM Membrane potentials in pinched-off presynaptic nerve ternimals monitored with a fluorescent probe: evidence that synaptosomes have potassium diffusion potentials. 1975 J. Physiol. (Lond.) pmid:49421
Kozlov VK [Lysosome-like alpha-granules of thrombocytes: detection by acridine orange treatment, properties and transformations during the course of blood coagulation reactions]. 1975 Tsitologiia pmid:51527
Betina V et al. Effects of antibiotics on the life cycle of Neurospora crassa. 1975 Folia Microbiol. (Praha) pmid:51812
Allam AM et al. Amylase of the thermophilic actinomycete Thermomonospora vulgaris. 1975 Z. Allg. Mikrobiol. pmid:848
Simonson LG et al. Characterization of an extracellular dextranase from Fusarium moniliforme. 1975 Appl Microbiol pmid:953
Ghelis C et al. The conformational oscillation of delta-chymotrypsin involvement of methionine-192. 1975 Eur. J. Biochem. pmid:1247
Fiddian-Green RG and Silen W Mechanisms of disposal of acid and alkali in rabbit duodenum. 1975 Am. J. Physiol. pmid:2019
Matheny JL and Ahlquist RP Metabolic inhibition and adrenoceptor interconversion. 1975 Arch Int Pharmacodyn Ther pmid:2120
Knauf PA et al. Calcium-potassium-stimulated net potassium efflux from human erythrocyte ghosts. 1975 J. Membr. Biol. pmid:2781
Wilkinson JH et al. Factors affecting the release of haemoglobin and enzymes from human erythrocytes. 1975 Ann. Clin. Biochem. pmid:15637925