Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Andrés MI et al. | Comparative effects of the metabolic inhibitors 2,4-dinitrophenol and iodoacetate on mouse neuroblastoma cells in vitro. | 1996 | Toxicology | pmid:8658553 |
Cojocel C and Hook JB | Effects of acute exposures to gentamicin on renal handling of proteins. | 1983 | Toxicology | pmid:6648982 |
Si EC et al. | Iodoacetic acid and related sulfhydryl reagents fail to inhibit cell-cell communication: mechanisms of immunotoxicity in vitro. | 1987 | Toxicology | pmid:3105120 |
Smith LL et al. | Factors affecting the efflux of paraquat from rat lung slices. | 1981 | Toxicology | pmid:7233444 |
Puntel RL et al. | Mitochondrial dysfunction induced by different organochalchogens is mediated by thiol oxidation and is not dependent of the classical mitochondrial permeability transition pore opening. | 2010 | Toxicol. Sci. | pmid:20573786 |
Kamendulis LM and Corcoran GB | Independence and additivity of cultured hepatocyte killing by Ca2+ overload and ATP depletion. | 1992 | Toxicol. Lett. | pmid:1488777 |
Shimada H et al. | The effects of sulfhydryl blockers and metal ions on nickel accumulation by rat primary hepatocyte cultures. | 2000 | Toxicol. Lett. | pmid:11137313 |
Eide I and Syversen TL | Uptake of elemental mercury by brain in relation to concentration of glutathione and activity of glutathione peroxidase. | 1983 | Toxicol. Lett. | pmid:6623515 |
Maduagwu EN | Differential effects on the cyanogenic glycoside content of fermenting cassava root pulp by beta-glucosidase and microbial activities. | 1983 | Toxicol. Lett. | pmid:6404010 |
Martenson CH et al. | The effect of acrylamide and other sulfhydryl alkylators on the ability of dynein and kinesin to translocate microtubules in vitro. | 1995 | Toxicol. Appl. Pharmacol. | pmid:7597712 |