Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Osteoarthritis, Spine D055013 2 associated lipids
Osteophyte D054850 2 associated lipids
Monckeberg Medial Calcific Sclerosis D050380 1 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Stroke D020521 32 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Thrombophilia D019851 6 associated lipids
Arthralgia D018771 8 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Reperfusion Injury D015427 65 associated lipids
Wounds and Injuries D014947 20 associated lipids
Vitamin D Deficiency D014808 13 associated lipids
Vascular Diseases D014652 16 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Thrombocytopenia D013921 15 associated lipids
Theileriasis D013801 7 associated lipids
Temporomandibular Joint Disorders D013705 4 associated lipids
Starvation D013217 47 associated lipids
Sarcoma 180 D012510 21 associated lipids
Rigor Mortis D012298 1 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Li Y et al. Analysis of iodinated haloacetic acids in drinking water by reversed-phase liquid chromatography/electrospray ionization/tandem mass spectrometry with large volume direct aqueous injection. 2012 J Chromatogr A pmid:22658134
Izumi M et al. RBCS1A and RBCS3B, two major members within the Arabidopsis RBCS multigene family, function to yield sufficient Rubisco content for leaf photosynthetic capacity. 2012 J. Exp. Bot. pmid:22223809
Fiaschi T et al. Redox Regulation of Nonmuscle Myosin Heavy Chain during Integrin Engagement. 2012 J Signal Transduct pmid:22220276
Vincent A et al. parkin-induced defects in neurophysiology and locomotion are generated by metabolic dysfunction and not oxidative stress. 2012 Hum. Mol. Genet. pmid:22215442
North SJ et al. Glycomic analysis of human mast cells, eosinophils and basophils. 2012 Glycobiology pmid:21725073
Ferreira-Gomes J et al. Dose-dependent expression of neuronal injury markers during experimental osteoarthritis induced by monoiodoacetate in the rat. 2012 Mol Pain pmid:22769424
Noel JM et al. Iodoacetic acid, but not sodium iodate, creates an inducible swine model of photoreceptor damage. 2012 Exp. Eye Res. pmid:22251455
Hardes K et al. Design, synthesis, and characterization of chromogenic substrates of coagulation factor XIIIa. 2012 Anal. Biochem. pmid:22683584
Sagar DR et al. The contribution of spinal glial cells to chronic pain behaviour in the monosodium iodoacetate model of osteoarthritic pain. 2011 Mol Pain pmid:22093915
Horisaki T et al. Isolation and characterization of monochloroacetic acid-degrading bacteria. 2011 J. Gen. Appl. Microbiol. pmid:22139456
Sacks DB et al. Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. 2011 Diabetes Care pmid:21617108
Mohan G et al. Application of in vivo micro-computed tomography in the temporal characterisation of subchondral bone architecture in a rat model of low-dose monosodium iodoacetate-induced osteoarthritis. 2011 Arthritis Res. Ther. pmid:22185204
Lee M et al. Direct sensing of endothelial oxidants by vascular endothelial growth factor receptor-2 and c-Src. 2011 PLoS ONE pmid:22145046
Potera C Nontoxic medical imaging agents form toxic DBPs. 2011 Environ. Health Perspect. pmid:22134135
Valdes AM et al. The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis. 2011 Ann. Rheum. Dis. pmid:21616913
Palaniappan KK et al. Isotopic signature transfer and mass pattern prediction (IsoStamp): an enabling technique for chemically-directed proteomics. 2011 ACS Chem. Biol. pmid:21604797
Lee Y et al. Monosodium iodoacetate-induced joint pain is associated with increased phosphorylation of mitogen activated protein kinases in the rat spinal cord. 2011 Mol Pain pmid:21599960
Gozal YM et al. Proteomic analysis of hippocampal dentate granule cells in frontotemporal lobar degeneration: application of laser capture technology. 2011 Front Neurol pmid:21577247
Seo MK et al. Repeated gene transfection impairs the engraftment of transplanted porcine neonatal pancreatic cells. 2011 Diabetes Metab J pmid:21537416
Ahn K et al. Mechanistic and pharmacological characterization of PF-04457845: a highly potent and selective fatty acid amide hydrolase inhibitor that reduces inflammatory and noninflammatory pain. 2011 J. Pharmacol. Exp. Ther. pmid:21505060