Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Osteoarthritis, Spine D055013 2 associated lipids
Osteophyte D054850 2 associated lipids
Monckeberg Medial Calcific Sclerosis D050380 1 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Stroke D020521 32 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Thrombophilia D019851 6 associated lipids
Arthralgia D018771 8 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Reperfusion Injury D015427 65 associated lipids
Wounds and Injuries D014947 20 associated lipids
Vitamin D Deficiency D014808 13 associated lipids
Vascular Diseases D014652 16 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Thrombocytopenia D013921 15 associated lipids
Theileriasis D013801 7 associated lipids
Temporomandibular Joint Disorders D013705 4 associated lipids
Starvation D013217 47 associated lipids
Sarcoma 180 D012510 21 associated lipids
Rigor Mortis D012298 1 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
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Authors Title Published Journal PubMed Link
Umbach AL and Siedow JN The reaction of the soybean cotyledon mitochondrial cyanide-resistant oxidase with sulfhydryl reagents suggests that alpha-keto acid activation involves the formation of a thiohemiacetal. 1996 J. Biol. Chem. pmid:8798784
Sammut EB and Kannegieter NJ Use of sodium monoiodoacetate to fuse the distal hock joints in horses. 1995 Aust. Vet. J. pmid:8787522
Barrigon S et al. Characterization of the calcium overload in cultured neonatal rat cardiomyocytes under metabolic inhibition. 1996 J. Mol. Cell. Cardiol. pmid:8782074
Hegy GB et al. Carboxymethylation of the human estrogen receptor ligand-binding domain-estradiol complex: HPLC/ESMS peptide mapping shows that cysteine 447 does not react with iodoacetic acid. 1996 Steroids pmid:8776799
Kanaani J et al. Probing the active site of Tritrichomonas foetus hypoxanthine-guanine-xanthine phosphoribosyltransferase using covalent modification of cysteine residues. 1996 Eur. J. Biochem. pmid:8774725
Wu Y et al. Alterations in reactive oxygen, pH, and calcium in astrocytoma cells during lethal injury. 1996 Am. J. Physiol. pmid:8772436
Ito Y et al. Oxidative stress increases glyceraldehyde-3-phosphate dehydrogenase mRNA levels in isolated rabbit aorta. 1996 Am. J. Physiol. pmid:8769737
Ballanyi K et al. Functional relevance of anaerobic metabolism in the isolated respiratory network of newborn rats. 1996 Pflugers Arch. pmid:8764977
Lawson SL et al. Effects of both shortening and lengthening the active site nucleophile of Bacillus circulans xylanase on catalytic activity. 1996 Biochemistry pmid:8756474
Dekker LR et al. Intracellular Ca2+, intercellular electrical coupling, and mechanical activity in ischemic rabbit papillary muscle. Effects of preconditioning and metabolic blockade. 1996 Circ. Res. pmid:8756000
Ishimizu T et al. Identification of histidine 31 and cysteine 95 in the active site of self-incompatibility associated S6-RNase in Nicotiana alata. 1995 J. Biochem. pmid:8749320
Bersinger NA et al. Pregnancy-associated plasma protein A (PAPP-A): measurement by highly sensitive and specific enzyme immunoassay, importance of first-trimester serum determinations, and stability studies. 1995 Reprod. Fertil. Dev. pmid:8743141
Liang CS Metabolic control of circulation. Effects of iodoacetate and fluoroacetate. 1977 J. Clin. Invest. pmid:874090
Morel MH and Bonicel J Determination of the number of cysteine residues in high molecular weight subunits of wheat glutenin. 1996 Electrophoresis pmid:8740165
Springer TA et al. Submit and disulfide structure of monomeric and dimeric forms of detergent-soluble HLA antigens. 1977 J. Biol. Chem. pmid:873911
Six S et al. Reactivity of the N-terminal cysteine residues in active and inactive forms of FNR, and O2-responsive, Fe containing transcriptional regulator of Escherichia coli. 1996 J. Inorg. Biochem. pmid:8729797
Hunter ES and Tugman JA Inhibitors of glycolytic metabolism affect neurulation-staged mouse conceptuses in vitro. 1995 Teratology pmid:8711618
Vospel'nikova ND et al. [Structural studies on D-glyceraldehyde-3-phosphate dehydrogenase from rat skeletal muscle]. 1977 Biokhimiia pmid:870089
Barnett DK and Bavister BD Inhibitory effect of glucose and phosphate on the second cleavage division of hamster embryos: is it linked to metabolism? 1996 Hum. Reprod. pmid:8671182
Boehm EA et al. The utilisation of creatine and its analogues by cytosolic and mitochondrial creatine kinase. 1996 Biochim. Biophys. Acta pmid:8664304