Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Pain D010146 64 associated lipids
Lung Neoplasms D008175 171 associated lipids
Wounds and Injuries D014947 20 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Sarcoma 180 D012510 21 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Osteoarthritis D010003 4 associated lipids
Coronary Disease D003327 70 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Glioma D005910 112 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Lymphoma D008223 18 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Brain Edema D001929 20 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

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Authors Title Published Journal PubMed Link
Chave KJ et al. Site-directed mutagenesis establishes cysteine-110 as essential for enzyme activity in human gamma-glutamyl hydrolase. 1999 Biochem. J. pmid:10527932
Patel AB et al. Arginine acts as a protective and reversal agent against glycolytic inhibitors in spermatozoa. 1999 Physiol Chem Phys Med NMR pmid:10535103
Lai SL et al. Interprotein disulfide bonds formed during isolation process tighten the structure of the postsynaptic density. 1999 J. Neurochem. pmid:10537073
Dirksen TR et al. Effect of metabolic inhibitors on bone lipid synthesis from radioactive bases. 1975 Sep-Oct J. Dent. Res. pmid:1058850
Chang YS et al. Shear-induced increase in hydraulic conductivity in endothelial cells is mediated by a nitric oxide-dependent mechanism. 2000 Arterioscler. Thromb. Vasc. Biol. pmid:10634798
Malcolm CS et al. Characterization of iodoacetate-mediated neurotoxicity in vitro using primary cultures of rat cerebellar granule cells. 2000 Free Radic. Biol. Med. pmid:10656296
Sinclair CJ et al. Stimulation of nucleoside efflux and inhibition of adenosine kinase by A1 adenosine receptor activation. 2000 Biochem. Pharmacol. pmid:10660114
Kim JS and Southard JH Effect of phospholipase A2 inhibitors on the release of arachidonic acid and cell viability in cold-stored hepatocytes. 2000 Cryobiology pmid:10679147
Yoshioka K et al. Characteristics of monocarboxylates as energy substrates other than glucose in rat brain slices and the effect of selective glial poisoning - a 31P NMR study. 2000 Neurosci. Res. pmid:10683525
Nagano H and To KA Purification of collagenase and specificity of its related enzyme from Bacillus subtilis FS-2. 2000 Biosci. Biotechnol. Biochem. pmid:10705465
López M et al. The action of Lonomia achelous caterpillars venom on human factor V. 2000 Thromb. Res. pmid:10706938
Miyagi M and Misono KS Disulfide bond structure of the atrial natriuretic peptide receptor extracellular domain: conserved disulfide bonds among guanylate cyclase-coupled receptors. 2000 Biochim. Biophys. Acta pmid:10719172
Hung AC et al. ATP-stimulated c-fos and zif268 mRNA expression is inhibited by chemical hypoxia in a rat brain-derived type 2 astrocyte cell line, RBA-2. 2000 J. Cell. Biochem. pmid:10723097
Koiwai H et al. Functional expression of two Arabidopsis aldehyde oxidases in the yeast Pichia pastoris. 2000 J. Biochem. pmid:10739959
Rasmussen JT et al. Cysteines involved in the interconversion between dehydrogenase and oxidase forms of bovine xanthine oxidoreductase. 2000 J. Dairy Sci. pmid:10750108
Martínez AD and Sáez JC Regulation of astrocyte gap junctions by hypoxia-reoxygenation. 2000 Brain Res. Brain Res. Rev. pmid:10751675
Larionova NA [The lipid composition characteristics of the blood serum and aortic wall in the modelling of different types of arteriosclerosis]. 2000 Fiziol Zh pmid:10758833
Bordji K et al. Evidence for the presence of peroxisome proliferator-activated receptor (PPAR) alpha and gamma and retinoid Z receptor in cartilage. PPARgamma activation modulates the effects of interleukin-1beta on rat chondrocytes. 2000 J. Biol. Chem. pmid:10766862
Abdel-Fattah AF and Badawi MA Effect of some agents on the activity of cell-free progesterone 11 alpha-hydroxylase and 11 beta-hydroxylase from Aspergillus niger 12Y. 1978 Zentralbl Bakteriol Naturwiss pmid:107681
Collard WT et al. Synthesis of homogeneous glycopeptides and their utility as DNA condensing agents. 2000 Carbohydr. Res. pmid:10782299