Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Pain D010146 64 associated lipids
Lung Neoplasms D008175 171 associated lipids
Wounds and Injuries D014947 20 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Sarcoma 180 D012510 21 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Osteoarthritis D010003 4 associated lipids
Coronary Disease D003327 70 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Glioma D005910 112 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Lymphoma D008223 18 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Brain Edema D001929 20 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Thote T et al. Localized 3D analysis of cartilage composition and morphology in small animal models of joint degeneration. 2013 Osteoarthr. Cartil. pmid:23747340
Kelly S et al. Spinal nociceptive reflexes are sensitized in the monosodium iodoacetate model of osteoarthritis pain in the rat. 2013 Osteoarthr. Cartil. pmid:23973147
Mapp PI et al. Differences in structural and pain phenotypes in the sodium monoiodoacetate and meniscal transection models of osteoarthritis. 2013 Osteoarthr. Cartil. pmid:23973148
Lee J et al. Coenzyme Q10 ameliorates pain and cartilage degradation in a rat model of osteoarthritis by regulating nitric oxide and inflammatory cytokines. 2013 PLoS ONE pmid:23894457
Wang XD et al. Estrogen aggravates iodoacetate-induced temporomandibular joint osteoarthritis. 2013 J. Dent. Res. pmid:23934157
Shao H et al. Intra-articular injection of xanthan gum reduces pain and cartilage damage in a rat osteoarthritis model. 2013 Carbohydr Polym pmid:23399228
Cialdai C et al. Comparison between oral and intra-articular antinociceptive effect of dexketoprofen and tramadol combination in monosodium iodoacetate-induced osteoarthritis in rats. 2013 Eur. J. Pharmacol. pmid:23891968
Escobar-Hoyos LF et al. Genotoxic and clastogenic effects of monohaloacetic acid drinking water disinfection by-products in primary human lymphocytes. 2013 Water Res. pmid:23602619
Dhaneshwar S and Patil D Chondromodulating chimeric prodrugs of diacetylrhein: synthesis and evaluation in monoiodoacetate-induced hyperalgesia. 2013 Med Chem pmid:22920092
Ferland CE et al. Antinociceptive effects of eugenol evaluated in a monoiodoacetate-induced osteoarthritis rat model. 2012 Phytother Res pmid:23015356
Camboim EK et al. Defluorination of sodium fluoroacetate by bacteria from soil and plants in Brazil. 2012 ScientificWorldJournal pmid:22619595
Cao S et al. A mitochondria-dependent pathway mediates the apoptosis of GSE-induced yeast. 2012 PLoS ONE pmid:22403727
Gallis JL et al. Resveratrol plus ethanol counteract the ethanol-induced impairment of energy metabolism: ³¹P NMR study of ATP and sn-glycerol-3-phosphate on isolated and perfused rat liver. 2012 Pharmacol. Res. pmid:22227530
Wang YC et al. Intracellular Na(+) and metabolic modulation of Na/K pump and excitability in the rat suprachiasmatic nucleus neurons. 2012 J. Neurophysiol. pmid:22773774
Li Y et al. Analysis of iodinated haloacetic acids in drinking water by reversed-phase liquid chromatography/electrospray ionization/tandem mass spectrometry with large volume direct aqueous injection. 2012 J Chromatogr A pmid:22658134
Cardador MJ and Gallego M Development of a method for the quantitation of chloro-, bromo-, and iodoacetic acids in alcoholic beverages. 2012 J. Agric. Food Chem. pmid:22225467
Wang XD et al. Progression of cartilage degradation, bone resorption and pain in rat temporomandibular joint osteoarthritis induced by injection of iodoacetate. 2012 PLoS ONE pmid:22984604
Lee JH et al. Alteration patterns of trabecular bone microarchitectural characteristics induced by osteoarthritis over time. 2012 Clin Interv Aging pmid:22956865
Moon SJ et al. Rebamipide attenuates pain severity and cartilage degeneration in a rat model of osteoarthritis by downregulating oxidative damage and catabolic activity in chondrocytes. 2012 Osteoarthr. Cartil. pmid:22890185
Downs I et al. The ROS scavenger, NAC, regulates hepatic Vα14iNKT cells signaling during Fas mAb-dependent fulminant liver failure. 2012 PLoS ONE pmid:22701598
Saba J et al. Increasing the productivity of glycopeptides analysis by using higher-energy collision dissociation-accurate mass-product-dependent electron transfer dissociation. 2012 Int J Proteomics pmid:22701174
Kaneda T et al. Key role of glycogen storage in high K+-induced contraction of the smooth muscles of the bovine trachea. 2012 J. Vet. Med. Sci. pmid:22673054
Mikulíková K et al. Study of saiga horn using high-performance liquid chromatography with mass spectrometry. 2012 ScientificWorldJournal pmid:22629195
Trivedi M et al. Improving the stability of the EC1 domain of E-cadherin by thiol alkylation of the cysteine residue. 2012 Int J Pharm pmid:22531851
Du J et al. The protein partners of GTP cyclohydrolase I in rat organs. 2012 PLoS ONE pmid:22479495
Kim JK et al. Effect of GCSB-5, a Herbal Formulation, on Monosodium Iodoacetate-Induced Osteoarthritis in Rats. 2012 Evid Based Complement Alternat Med pmid:22474519
Thakur M et al. Characterisation of a peripheral neuropathic component of the rat monoiodoacetate model of osteoarthritis. 2012 PLoS ONE pmid:22470467
Sun L et al. N-acetylcysteine protects against apoptosis through modulation of group I metabotropic glutamate receptor activity. 2012 PLoS ONE pmid:22442667
Jia D et al. Fibronectin matrix-mediated cohesion suppresses invasion of prostate cancer cells. 2012 BMC Cancer pmid:22433434
Weinans H Periarticular bone changes in osteoarthritis. 2012 HSS J pmid:22423223
Okun A et al. Afferent drive elicits ongoing pain in a model of advanced osteoarthritis. 2012 Pain pmid:22387095
Sixt SU et al. Distinct proteasome subpopulations in the alveolar space of patients with the acute respiratory distress syndrome. 2012 Mediators Inflamm. pmid:22363101
Menkhorst EM et al. Decidual-secreted factors alter invasive trophoblast membrane and secreted proteins implying a role for decidual cell regulation of placentation. 2012 PLoS ONE pmid:22359590
Kelly S et al. Spontaneous firing in C-fibers and increased mechanical sensitivity in A-fibers of knee joint-associated mechanoreceptive primary afferent neurones during MIA-induced osteoarthritis in the rat. 2012 Osteoarthr. Cartil. pmid:22285737
Ahn CM et al. Decreased lung hyaluronan in a model of ARDS in the rat: effect of an inhibitor of leukocyte elastase. 2012 Ups. J. Med. Sci. pmid:22283425
Yu MK et al. Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy. 2012 Theranostics pmid:22272217
Fiaschi T et al. Redox Regulation of Nonmuscle Myosin Heavy Chain during Integrin Engagement. 2012 J Signal Transduct pmid:22220276
Vincent A et al. parkin-induced defects in neurophysiology and locomotion are generated by metabolic dysfunction and not oxidative stress. 2012 Hum. Mol. Genet. pmid:22215442
Egger S et al. Structural and kinetic evidence that catalytic reaction of human UDP-glucose 6-dehydrogenase involves covalent thiohemiacetal and thioester enzyme intermediates. 2012 J. Biol. Chem. pmid:22123821
Ford AP In pursuit of P2X3 antagonists: novel therapeutics for chronic pain and afferent sensitization. 2012 Purinergic Signal. pmid:22095157
Wang H et al. Proteomic analysis of early-responsive redox-sensitive proteins in Arabidopsis. 2012 J. Proteome Res. pmid:22050424
Wang S and Kaltashov IA A new strategy of using O18-labeled iodoacetic acid for mass spectrometry-based protein quantitation. 2012 J. Am. Soc. Mass Spectrom. pmid:22562395
Lin X et al. B2A peptide induces chondrogenic differentiation in vitro and enhances cartilage repair in rats. 2012 J. Orthop. Res. pmid:22271086
Izumi M et al. Local ASIC3 modulates pain and disease progression in a rat model of osteoarthritis. 2012 J. Biomed. Sci. pmid:22909215
Ashkavand Z et al. Silymarin potentiates the anti-inflammatory effects of Celecoxib on chemically induced osteoarthritis in rats. 2012 Phytomedicine pmid:22925727
Schuelert N and McDougall JJ Involvement of Nav 1.8 sodium ion channels in the transduction of mechanical pain in a rodent model of osteoarthritis. 2012 Arthritis Res. Ther. pmid:22225591
Ferreira-Gomes J et al. Dose-dependent expression of neuronal injury markers during experimental osteoarthritis induced by monoiodoacetate in the rat. 2012 Mol Pain pmid:22769424
Noel JM et al. Iodoacetic acid, but not sodium iodate, creates an inducible swine model of photoreceptor damage. 2012 Exp. Eye Res. pmid:22251455
Hardes K et al. Design, synthesis, and characterization of chromogenic substrates of coagulation factor XIIIa. 2012 Anal. Biochem. pmid:22683584
Rao Y et al. Mapping of sulfur metabolic pathway by LC Orbitrap mass spectrometry. 2012 Anal. Chim. Acta pmid:22405311