Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Pain D010146 64 associated lipids
Lung Neoplasms D008175 171 associated lipids
Wounds and Injuries D014947 20 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Sarcoma 180 D012510 21 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Osteoarthritis D010003 4 associated lipids
Coronary Disease D003327 70 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Glioma D005910 112 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Lymphoma D008223 18 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Brain Edema D001929 20 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

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Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Cannon JR et al. The effects of fructose on adenosine triphosphate depletion following mitochondrial dysfunction and lethal cell injury in isolated rat hepatocytes. 1991 Toxicol. Appl. Pharmacol. pmid:2020968
Martenson CH et al. The effect of acrylamide and other sulfhydryl alkylators on the ability of dynein and kinesin to translocate microtubules in vitro. 1995 Toxicol. Appl. Pharmacol. pmid:7597712
Powell SR and McCay PB Inhibition of doxorubicin-initiated membrane damage by N-acetylcysteine: possible mediation by a thiol-dependent, cytosolic inhibitor of lipid peroxidation. 1988 Toxicol. Appl. Pharmacol. pmid:3194911
Gillies PJ et al. Inhibition of sterologenesis but not glycolysis in 2,5-hexanedione-induced distal axonopathy in the rat. 1981 Toxicol. Appl. Pharmacol. pmid:6266076
Tobey RA et al. Zinc-induced resistance to alklylating agents: lack of correlation between cell survival and metallothionein content. 1982 Toxicol. Appl. Pharmacol. pmid:7112586
EBE M Effect of glutamic acid, NaCN and monoiodoacetic acid on the potential changes of isolated toad's brain. 1952 Tohoku J. Exp. Med. pmid:13005477
Ohgawara H et al. Monolayer-forming islet cell culture from neonatal pig pancreas: using sequential treatment with EDTA-dispase and monoiodoacetic acid for preparation and purification. 1987 Tohoku J. Exp. Med. pmid:2450412
Maekawa Y et al. A tetrazolium-based colorimetric assay for metabolic activity of stored blood platelets. 2003 Thromb. Res. pmid:12818255
López M et al. The action of Lonomia achelous caterpillars venom on human factor V. 2000 Thromb. Res. pmid:10706938
Mitra G and Ng PK Hepatitis B virus associated DNA polymerase inactivation in factor IX concentrates. 1986 Thromb. Res. pmid:3705011
Cox CP and Quissell DO A novel platelet-activating protein derived from rat submandibular glands. 1985 Thromb. Res. pmid:4049321
Hashimoto S et al. Dependence of platelet adenyl cyclase system on oxidative phosphorylation. 1975 Thromb Diath Haemorrh pmid:171798
Yu MK et al. Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy. 2012 Theranostics pmid:22272217
Hunter ES and Tugman JA Inhibitors of glycolytic metabolism affect neurulation-staged mouse conceptuses in vitro. 1995 Teratology pmid:8711618
Miller TJ Cleft palate formation: the effects of fasting and iodoacetic acid on mice. 1973 Teratology pmid:4725547
Shi H and Adams C Rapid IC-ICP/MS method for simultaneous analysis of iodoacetic acids, bromoacetic acids, bromate, and other related halogenated compounds in water. 2009 Talanta pmid:19559915
Gendrot F et al. Valine transport and biodiversity of Leuconostoc wild strains from French raw milk cheeses. 2000 Syst. Appl. Microbiol. pmid:11249015
Bickler PE and Kelleher JA Fructose-1,6-bisphosphate stabilizes brain intracellular calcium during hypoxia in rats. 1992 Stroke pmid:1440710
Toda N Calcium independent contraction induced by iodoacetic acid in isolated cerebral arteries. 1984 May-Jun Stroke pmid:6729876
Vinall PE and Simeone FA Effects of oxygen and glucose deprivation on vasoactivity in isolated bovine middle cerebral arteries. 1986 Sep-Oct Stroke pmid:3764969